Cytisine Powder

KINTAI is a supplier of plant active ingredients with more than 10 years of professional experience. It has specialized in the research, development, and production of cytisine for many years. It uses silica gel chromatography separation and extraction technology to produce 98% cytisine powder with high yield. The products are of high purity and support testing by third-party professional institutions.

Cytisine Powder is one of the main alkaloids in Sophora alopecuroide. It has the functions of expectorating cough, anti-arrhythmia, antibacterial, anti-infection and promoting brain circulation. It can be used to produce smoking cessation medicine, first aid medicine, and cough medicine. Please contact us at health@kintaibio.com.

• Purity: 98% cytisine, in line with European and American pharmacopoeia standards.
• Packaging: 10kg/barrel, lined with double-layer sterile bags or 0.5-5kg/bag, aluminum platinum bag vacuum packaging.
• Extraction Source: Sophora alopecuroides, after strict quality control, to ensure the stability and purity of each batch of products.

1. Nicotine replacement for smoking cessation
This is the most extensively researched and well-documented core function of cytisine. Its molecular structure is similar to nicotine, allowing it to bind to nicotine acetylcholine receptors in the brain, mimicking some of the physiological effects of nicotine. This can effectively alleviate withdrawal symptoms such as cravings, anxiety, and irritability during the quitting process. Furthermore, as a partial agonist, the euphoria it produces is far less than that of nicotine, helping to gradually reduce smokers' nicotine dependence and ultimately achieve safe smoking cessation. In some countries, it has been developed as a prescription smoking cessation medication.

2. Respiratory stimulation and cerebral circulation-enhancing effects
Cytisine stimulates chemoreceptors in the carotid body, reflexively stimulating the respiratory center and causing deeper and faster breathing. This respiratory stimulation is reflected in its traditional use. It may also stimulate cerebral blood circulation by stimulating the sympathetic nervous system. However, this potent physiological stimulation carries risks, such as cardiac arrhythmias and elevated blood pressure, and its use must be carefully monitored.

3. Broad Potential Pharmacological Activities
Preclinical studies (primarily in vitro and animal studies) suggest that cytisine may possess a variety of pharmacological potential, including antiarrhythmic, antibacterial, anti-inflammatory, anti-ulcer, and leukocyte-enhancing properties. It must be noted that most of these activities are in the very early stages of research and exploration and have not yet been fully validated in human clinical trials. Therefore, claims regarding their actual medical uses cannot be made at this time.

4. Potent Anticancer Activity
Similarly, some laboratory studies have shown that cytisine can inhibit the proliferation or induce apoptosis of certain cancer cells in cell models, demonstrating potential anti-tumor properties. However, this is still a long way from becoming a mature anticancer drug.

5. Significant Plant Growth Regulation​​​​​​​
In agriculture, cytisine, a natural plant product, has been found to regulate the growth of certain plants, potentially affecting seed germination or seedling growth. This falls within the research area of ​​plant allelopathic effects and represents a unique non-medical application, but its practical application still requires further development.

6. Antitussive and Expectorant Function
Due to its respiratory stimulant properties, cytisine has been used in traditional medicine to treat respiratory ailments such as chronic bronchitis, where it is believed to have certain expectorant and antitussive properties. 

1. Smoking Cessation Aid

Cytisine is an alkaloid with a structure similar to nicotine. It binds to the same receptors in the brain, mimicking the effects of nicotine, thereby alleviating withdrawal symptoms such as cravings and anxiety during smoking cessation. Some studies have shown some effectiveness in smoking cessation, particularly in Eastern European countries.

2. Stimulant and Performance-Enhancing Effects

This ingredient stimulates the nervous system, increasing heart rate and blood pressure, and temporarily boosting energy metabolism and endurance. It has been abused as a sports stimulant and weight loss product.

 As an alkaloid, cytisine, while exerting its pharmacological effects (such as its use in smoking cessation), may also cause a series of side effects. Its adverse reactions mainly stem from its effects on the nervous and cardiovascular systems.

Common side effects include gastrointestinal reactions such as dry mouth, nausea, abdominal discomfort, and indigestion, as well as neurological symptoms such as dizziness, headache, and sleep disturbances (such as insomnia or vivid dreams). Some users may experience cardiovascular reactions such as fluctuations in blood pressure and rapid heartbeat; although not common, these require vigilance. It is worth noting that overdose may lead to more serious poisoning reactions, such as tremors, sweating, visual and auditory disturbances, and even respiratory depression.

Therefore, the use of cytisine products, especially over-the-counter products, must be under the guidance of a doctor or pharmacist, strictly adhering to the recommended dosage, and closely monitoring the body's reactions to ensure medication safety and avoid health risks.

Q1:Can cytisine help you quit smoking?

A1:Cytisine is an effective smoking cessation medication. It is a plant alkaloid that works similarly to nicotine, binding to nicotine receptors in the brain to reduce withdrawal symptoms and cravings. However, it has a lower affinity for nicotine, resulting in a less pleasant smoking experience while using it, which helps break the physiological dependence.

Q2:What is another name for cytisine?

A2:Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae.  It is a plant compound with significant pharmacological properties. Its molecular structure is similar to nicotine, and it can competitively bind to the same nicotine acetylcholine receptors in the brain. This property allows it to mimic the effects of nicotine, alleviating withdrawal symptoms; on the other hand, its weaker stimulating effect helps users gradually wean themselves off nicotine dependence. Based on this principle, septin has been developed as an effective smoking cessation drug and has been used in Eastern Europe for many years. In recent years, international research has also confirmed its efficacy, making it an inexpensive and effective nicotine replacement therapy that helps smokers overcome physiological addiction and ultimately quit smoking successfully.​​​​​​​

Q3:Is cytisine safe​?

Cytisine is generally considered safe for most adults when used at the recommended dosage for smoking cessation, typically over a 25-day course. However, it is not without side effects. Common, usually mild, reactions can include dry mouth, nausea, stomach upset, and mild sleep disturbances. Because cytisine works similarly to nicotine, it can affect the cardiovascular and nervous systems, potentially causing changes in blood pressure or heart rate.