Oleanolic Acid Powder
CAS No: 508-02-1
Specification: 60%-98% oleanolic acid
Appearance: White powder
Test Method: Titration
Extract Source:100% Natural
Origin:China
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Payment: Multiple terms acceptable like T/T, L/C, DA
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Oleanolic Acid powder Manufacturer and Supplier
Choose Healthkintai®, and select high-quality Oleanolic Acid powder. Our product is strictly sourced from fresh leaves of the plant, belonging to the Oleaceae family. The latest clinical and research evidence indicates that oleanolic acid is the core active ingredient, the cornerstone of Kintai's extract's exceptional quality.
Leveraging cutting - edge extraction and purification technologies, we offer pharmaceutical - grade products with a purity that constantly surpasses 98%. As a vital naturally - occurring pentacyclic triterpenoid (CAS: 508 - 02 - 1), Oleanolic acid is in its core bioactive form, ensuring high bioavailability for various uses.Our GMP - compliant production process guarantees outstanding stability and dependability. Oleanolic acid powder is widely used.We also have oleanolic acid extract from Coleus Forskohlii.Click here to learn more. If you want to buy Oleanolic acid powder, please contact us directly!
Physicochemical properties of oleanolic acid
CAS Number |
508-02-1 |
Molecular formula: |
C30H48O3 |
Molecular weight: |
456.71 |
Melting point: |
308 ℃~ 310 ℃[ α] 20D+68 ° to+78 ° (C=0.15, chloroform) |
Oleanolic acid is a white acicular crystal (ethanol), odorless and tasteless. It is unstable to acid and alkali, insoluble in water, but soluble in methanol, ethanol, ether, acetone, and chloroform. |
Product quality specification & standard
Product name |
Olea Leaf Extract |
Extract source |
Leaves of oleander |
Extraction Solvent |
Water/Ethyl alcohol |
Appearance |
White crystalline powder |
Solubility |
Insoluble in water, but soluble in methanol, ethanol, ether, acetone, and chloroform |
Identification |
TLC, HPLC |
Sulfated Ash |
NMT 0.5% |
Heavy metals |
NMT 20 PPM |
Loss On Drying |
NMT 5.0% |
Powder size |
80Mesh, NLT90% |
Assay of 98% oleanolic acid (HPLC test, percent, Standard in House) |
Min. 98.0% |
Microbiological Quality (Total viable aerobic count) |
|
- Bacteria, CFU/g, not more than |
NMT 103 |
- Moulds and yeasts, CFU/g, not more than |
NMT 102 |
- E.coli, Salmonella, S. aureus, CFU/g |
Absence |
Shelf life |
Powder storage at room temperature 24 months |
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Oleanolic Acid Dosage
Application Field |
Target Population & Indication |
Professional Dosage Recommendation |
Precautions |
Healthcare |
Adults with chronic hepatitis or hepatic dysfunction for adjuvant treatment |
Oral: 30 mg (3 tablets of 10 mg each) TID, or as per medical prescription |
Under physician supervision; regular liver function monitoring is required. Contraindicated for pregnant/lactating women and children due to insufficient safety data. |
Dietary Supplements |
Adults for metabolic regulation and immune enhancement |
50–100 mg daily, divided into 1–2 administrations |
Avoid prolonged high-dose use; consult a healthcare provider before co-administration with other drugs to mitigate potential interactions. |
Cosmetics |
All skin types for improving dermal elasticity and anti-aging |
Formulated at 0.1%–2% concentration in skincare products; adhere to product-specific instructions |
Perform patch testing prior to initial use; avoid ocular contact. Exercise caution in cases of cutaneous lesions or allergic predisposition. |
Oleanolic Acid for Hair
Oleanolic acid, through its multiple anti-inflammatory, antioxidant, and antibacterial mechanisms, can effectively improve the health of the scalp, strengthen hair roots, indirectly reduce hair loss caused by scalp problems, and promote healthy hair growth. It is becoming a popular natural hair care active ingredient, being tested in products such as anti-hair loss shampoos and scalp care serums.
Effects of oleanolic acid on diabetic nephropathy
Oleanolic acid (OA), a pentacyclic triterpenoid compound, is widely distributed in plants of the olive family. It possesses antioxidant, anti-inflammatory, and anti-tumor pharmacological activities. It can reduce renal cell apoptosis, alleviate renal damage, and improve clinical symptoms of DN by lowering oxidative stress, inhibiting inflammation, and alleviating endoplasmic reticulum stress.
Oleanolic acid can also reduce NF-κB levels, downregulate caspase-9 protein expression, correct abnormal glucose and lipid metabolism, inhibit the expression of proinflammatory cytokines, and prevent the onset and progression of inflammation.
Oleanolic Acid For skin
Oleanolic acid powder, a pentacyclic triterpenoid naturally found in plants like olives and Ligustrum lucidum, is an excellent skincare ingredient.
Anti-inflammatory and soothing: These are oleanolic acid's core benefits. It effectively inhibits the release of inflammatory factors, reducing skin inflammation, and is very helpful in improving inflammatory skin conditions such as acne, eczema, and dermatitis.
Antibacterial and anti-acne: Oleanolic acid has a certain inhibitory effect on acne-causing bacteria (such as Propionibacterium acnes). Combined with its anti-inflammatory properties, it is an effective ingredient for combating acne.
Protective and repairing: It helps strengthen the skin's barrier function and improves its resistance to external irritants. It also promotes wound healing and helps repair damaged skin tissue.
Whitening and brightening: Some studies have shown that oleanolic acid may reduce melanin production by inhibiting tyrosinase activity, potentially brightening the skin and fading dark spots.
Oleanolic Acid Benefits
Liver Protection: Oleanolic acid can lower alanine aminotransferase (ALT), reduce liver cell damage, promote liver cell regeneration, and protect against chemical liver damage. It is often used as an adjunct to the treatment of hepatitis.
Anti-inflammatory and Immunomodulatory: It effectively alleviates inflammatory responses by inhibiting the release of inflammatory factors (such as TNF-α and IL-6). It can also regulate immune function and improve symptoms of autoimmune diseases.
Antioxidant and Anti-Aging: As an antioxidant, it scavenges free radicals, mitigates oxidative stress damage to the skin and cells, and protects collagen. It is often used in skincare products for anti-wrinkle and skin-brightening effects.
Antibacterial and Antiviral: It has inhibitory effects on Staphylococcus aureus and Streptococcus, among others, and exhibits some antiviral activity.
Lipid-Lowering and Cardiovascular Protection: It can lower blood cholesterol and triglyceride levels, reduce the risk of atherosclerosis, and protect cardiovascular health.
Oleanolic Acid Uses
1.In the pharmaceutical field: A core ingredient for liver and metabolic health
Oleanolic acid is a key active ingredient in many hepatoprotective medications, such as the popular bifendate tablets. It significantly reduces serum transaminase levels, mitigates chemical or immune liver damage, and promotes liver cell regeneration. It is widely used clinically as an adjunct to the treatment of acute and chronic hepatitis. Furthermore, by regulating lipid metabolism, it effectively lowers blood cholesterol and triglycerides, playing a positive role in preventing metabolic diseases such as atherosclerosis and fatty liver disease.
2.In the skincare field: A multifunctional ingredient with anti-inflammatory and anti-aging properties
In cosmetics, oleanolic acid is a highly sought-after multifunctional active ingredient. Its excellent anti-inflammatory and antibacterial properties effectively soothe inflammatory conditions such as acne and eczema, making it suitable for sensitive and acne-prone skin. Furthermore, as a powerful natural antioxidant, it neutralizes free radicals, mitigates photoaging damage, and inhibits collagen degradation, thereby delaying the formation of wrinkles and firming the skin.
3.Daily Chemicals and Hair Care: A Guardian of Scalp Health
Oleanolic acid is increasingly being incorporated into daily chemical products such as shampoos and scalp serums. Its anti-inflammatory properties help relieve scalp itching, redness, and seborrheic dermatitis. Its antibacterial properties inhibit the overgrowth of fungi like Malassezia, thus addressing the root causes of dandruff. By improving the scalp's microenvironment and strengthening hair follicle health, it can indirectly reduce hair loss and promote strong hair growth.
Why Choose KINTAI Oleanolic Acid?
- High-quality, traceable raw materials: Selected high-content native botanicals (such as Ligustrum lucidum and olives) are used as raw materials, utilizing green extraction processes to ensure natural, pure ingredients with high active content, guaranteeing product safety and efficacy from the source.
- Flexible Customization and Precise Adaptation: Supporting customization of multiple parameters (such as purity, particle size, and solvent options), we provide personalized product solutions based on customer R&D needs and application scenarios (pharmaceuticals, cosmetics, and health supplements), effectively improving development efficiency.
- Highly Standardized, Stable and Reliable: Strictly adhering to the GMP quality management system and standardized production controls throughout the entire process ensure high batch-to-batch consistency and robust stability. Products comply with pharmacopoeias and industry standards, guaranteeing the reliability of R&D data and the quality of end products.
FAQ
Q1:What does oleanolic acid do for skin?
A1:Oleanolic acid is a potent soothing ingredient for skin. This ingredient is found in a wide range of foods (including olive oil), medicinal herbs, and plants.
Q2:Is oleanolic acid good for hair?
A2:Experts who have conducted research and development concluded that Oleanolic acid powder has anti-inflammatory and hair growth-fostering properties. Thus, it is rich in antioxidants.
Q3:What is another name for oleanolic acid?
A3:Oleanolic acid (Synonyms: Oleanic acid; Caryophyllin) Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
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