Fisetin Powder

Plant Source: Cotinus coggygria
Extract Source:100% Natural
Origin:China
Specification: 50%, 85%, 98% Fisetin
Appearance: Yellow powder
CAS No: 528-48-3
Test Method: HPLC
Lead time: 1-3 days
Shelf Life: 2 years
Sample: Free sample available
Applications:Health Care Products, Medicine, Cosmetics
Storage: Store in a well-closed container away from moisture and direct sunlight.Keep in cool dry place
Content: Vegan, Gluten-Free, Natural, Non-GMO, Non-additive
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Payment: Multiple terms acceptable like T/T, LC, DA
KINTAI's Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, Non-Irradiated/treat by heat only.
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Fisetin Powder Manufacturer and Supplier​​​​​​​

Healthkintai® stands out as a trusted supplier of Fisetin Powder, offering a comprehensive range of specifications(10%、20%、50%、85%、98%Fisetin) to meet diverse industry needs. What truly distinguishes us from other providers is our unwavering commitment to quality and compliance, backed by a suite of prestigious certifications including GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER, and HALAL. These certifications serve as a testament to our adherence to rigorous international standards throughout the production and supply chain processes, ensuring that every batch of Fisetin Powder we provide is of the highest quality, safety, and reliability.

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To further demonstrate our confidence in our products, we are pleased to offer free samples, allowing clients to experience the excellence of our Fisetin Powder firsthand. Whether for applications in cosmetics, pharmaceuticals, food and beverages, or other fields, Healthkintai® is dedicated to delivering Fisetin Powder that not only meets but exceeds international standards, making us the ideal partner for your business.​

KINTAI Fisetin Powder Specification

Product name

Fisetin

Extract source

Cotinus coggygria

Extraction Solvent

Water/Ethyl alcohol

Appearance

Yellow powder

Identification

HPLC

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Specification

80% TA (Feed Grade)

Microbiological Quality (Total viable aerobic count)

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In Tight, Light-resistant and Dry Place. Avoid Direct Sunshine. Country of Origin: China

Shelf life

Powder storage at room temperature 24 months

Fisetin Powder Chemical & Physical Properties

CAS Number

528-48-3

Density

1.2981 (rough estimate)

Molecular Formula

C15H10O6

Molecular Weight

286.24

Melting Point

>330 ℃ (lit.)

Boiling Point

348.61 ℃ (rough estimate)

Solubleness

Soluble in DMSO (a little), methanol (a little)

Test Method

HPLC

Structure of Fisetin


Interested?We'd love to send you a free symple!   CONTACT US>>>


Effort of Fisetin against venous thrombosis

 The leaves of Cotinus coggygria can eliminate fever and relieve jaundice caused by alcohol. The leaves can be boiled in water and taken orally, indicating that they can be used to treat icteric hepatitis and have a liver-protecting effect.Fisetin can exert its antithrombotic effect by downregulating PLG and PAI-1. The positive control drug aspirin used in this experiment may not exert its antithrombotic effect through the AT-III and PLG pathways.

Effort of Fisetin against venous thrombosis

Fisetin Powder Benefits

1. Powerful Antioxidant
Fisetin effectively neutralizes free radicals in the body and reduces oxidative stress. Oxidative stress is a major factor in cell damage, aging, and various chronic diseases (such as cancer and heart disease). It achieves this by directly scavenging free radicals and boosting the body's own antioxidant system (e.g., by increasing glutathione levels).

2. Anti-inflammatory Properties
Fisetin can help suppress inflammatory responses. It inhibits key inflammatory signaling pathways, such as NF-κB, and reduces the production of inflammatory factors (such as TNF-α and IL-6).

3. Senolytic Activity
This is the area of ​​research that has attracted the most attention in recent years regarding fisetin. It is considered a "senolytic" compound, meaning it can selectively eliminate senescent cells. Fisetin precisely induces apoptosis (programmed cell death) in these senescent cells, thereby eliminating them.
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4. Neuroprotection and Brain Health
Based on its antioxidant, anti-inflammatory, and senescent cell-clearing properties, fisetin has shown potential to protect the brain. In preclinical studies of Alzheimer's and Parkinson's diseases, fisetin has shown potential to reduce amyloid plaques (associated with Alzheimer's disease), protect neurons, and slow cognitive decline.

5. Supports Heart Health

By reducing oxidative stress and inflammation, fisetin may help improve vascular function and lower blood pressure, thereby protecting the cardiovascular system. It may also improve endothelial function (the health of the blood vessel lining) and reduce risk factors for atherosclerosis.

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Fisetin Powder Applications

1. Anti-aging
This is the most cutting-edge application area for fisetin. Its core application lies in its potent senolytic activity. Fisetin selectively induces apoptosis and eliminates senescent cells, thereby alleviating tissue dysfunction caused by the inflammatory factors secreted by senescent cells.

2. Neuroprotection and Brain Health
Fisetin has great potential in combating neurodegenerative diseases. Its antioxidant and anti-inflammatory properties help protect neurons from oxidative damage and neuroinflammation. Furthermore, it promotes the expression of brain-derived neurotrophic factor (BDNF), enhancing memory and learning. Fisetin has been shown to reduce the accumulation of pathological proteins and slow cognitive decline, providing new avenues for the prevention and treatment of these diseases.

3. Sports Nutrition
In sports nutrition, fisetin is primarily used to alleviate exercise-induced fatigue and accelerate recovery. Intense exercise generates a large number of free radicals, leading to oxidative stress and muscle damage. Fisetin's potent antioxidant capacity can neutralize free radicals and reduce oxidative damage to muscle cells. Its anti-inflammatory properties also help reduce post-exercise inflammation and alleviate muscle soreness, thereby improving performance and shortening recovery time.

4. Skin Health and Beauty
In the cosmetics and skincare industry, fisetin is used for its photoprotective and anti-aging properties. It effectively combats ultraviolet (UV) radiation-induced skin damage, reducing oxidative stress and inflammation, thereby preventing photoaging, wrinkling, and hyperpigmentation. As a functional ingredient in skincare products, fisetin helps maintain skin elasticity, moisturization, and an overall youthful appearance.

5. Metabolic Health
Fisetin also plays a role in improving metabolic syndrome. Studies have shown that it can help regulate blood sugar levels by enhancing insulin sensitivity and protecting pancreatic beta cells. Its anti-inflammatory properties also help improve adipose tissue inflammation, potentially aiding in the management of obesity and related metabolic disorders (such as type 2 diabetes), making it a promising target for health food development.

​​​​​​​6. Cancer Prevention
Although still in the basic research phase, fisetin shows promise in cancer chemoprevention. Laboratory studies have shown that it can inhibit the growth of various cancer cells by inducing apoptosis, inhibiting cancer cell proliferation and angiogenesis. Although it has not yet become an independent treatment, its potential as an auxiliary means or preventive agent is being actively explored, providing new ideas for future anti-cancer strategies.

Fisetin Powder Applications

FAQ

1.Q: Is the powder suitable for vegetarians and vegans?

   A: Yes, It is plant-derived and entirely suitable for vegetarians and vegans.

2.Q: What is the recommended dosage for the product?

   A: The recommended dosage varies based on individual needs and health conditions. We recommend consulting with a healthcare professional for personalized advice.​​​​​​​

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