Genistein Powder

Plant Source: Fructus Sophorae
Extract Source:100% Natural
Origin:China
Specification: 98% Isoflavones Genistein (Other specifications can be customized)
Appearance: Off Yellow powder
CAS No: 446-72-0
Test Method: HPLC
Lead time: 1-3 days
Shelf Life: 2 years
Sample: Free sample available
Content: Natural, Non-GMO, Non-additive
Applications:Health Care Products, Medicine, Cosmetics
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Payment: Multiple terms acceptable like T/T, L/C, DA
Storage: Store in a well-closed container away from moisture and direct sunlight.Keep in cool dry place
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Genistein Powder Manufaturer and Supplier

Genistein powder, a natural isoflavone primarily derived from leguminous plants, exhibits a broad spectrum of pharmacological activities and is often referred to as a "natural phytoestrogen". It is predominantly found in species such as the pagoda tree (Sophora japonica) and is abundantly distributed across multiple regions of China, including Henan, Tianjin, Hebei, Shandong, and Shaanxi. 

kintai genistein

Xi'an Kintai Biotechnology Co., Ltd. is a professional plant extract manufacturer. We are committed to providing our customers with high-quality genistein raw materials, helping them create innovative products that align with market trends. Currently, genistein is widely used in medicine, health supplements, and cosmetics. Its significant anti-cancer, anti-aging, antioxidant, and anti-osteoporosis benefits make it a highly sought-after core ingredient in the healthcare industry. Choose Kintai and let us empower your brand value and market competitiveness with our high-quality raw materials and professional support. 

KINTAI Genistein Powder COA

KINTAI Genistein Powder COA


Interested?We'd love to send you a free sample!


Genistein Powder Quality Specification&Standard 

Product Name

Genistein Powder

Extraction source

Fabaceae Genista (Gorse)

Assay

98%

Appearance

Off Yellow powder

Solubility

Soluble in commonly used organic solvents, almost insoluble in water, soluble in dilute alkali

Extract Solvent

Ethanol

 

Loss on Drying

NMT2.0%

Pb

NMT1ppm

As

NMT1ppm

Hg

NMT0.1ppm

Cd

NMT1ppm

Total Plate Count

NMT1000cfu/g

Total Yeast & Mold

NMT100cfu/g

Storage conditions

Preserve in tight containers at a Cool & dry place.(2℃--- 8℃)

Keep away from strong light and heat.

Chromatogram of Kintai Genistein

Chromatogram of Genistein

Chemical&Physical Properties of Genistein

Property

Description

Chemical Name

4',5,7-Trihydroxyisoflavone

Synonyms

Genistein, Genisteol, Prunetol

CAS Number

446-72-0

Molecular Formula

C₁₅H₁₀O₅

Molecular Weight

270.24 g/mol

Appearance

Off-white to pale yellow crystalline powder

Melting Point

297 °C - 298 °C (decomposition)

Solubility

Soluble in: DMSO, DMF, ethanol, methanol.
Sparingly soluble in: Ethers, chloroform.
Practically insoluble in: Water, petroleum ether. Solubility increases in alkaline aqueous solutions.

pKa Values

~7.2 (phenolic hydroxyl group), ~9.9 (phenolic hydroxyl group)

Log P (Octanol-Water Partition Coefficient)

~2.5 - 3.1 (Indicates lipophilicity)

UV-Vis Absorption (λmax)

~259 - 261 nm (shoulder), ~330 nm (in methanol)

Stability

Stable under recommended storage conditions. Sensitive to light and oxygen. Solutions are stable for up to 24 hours at 2-8°C.

Genistein

Kintai Genistein Production Process flow
  • Raw Material Collection: Starting with the extraction of Sophoricoside from the plant source.
  • Hydrolysis Process: Using ethanol to hydrolyze Sophoricoside into high-purity Genistein.
  • Refining & Testing: Involving multiple refinement and quality control checks to ensure the final product meets the required standards.

kintai process flow

Genistein for Women Health

The effect of genistein on female hormones is not a single 'supplementation' or 'antagonism', but an 'bidirectional'regulation, and its ultimate effect depends on the woman's own physiological state and hormone levels. 

Physiological Stage

Endogenous Estrogen Level

Endogenous Estrogen Level

Impact on Women

Reproductive Age

High

Anti-Estrogenic Effect (Competition/Inhibition)

May help balance hormone levels and reduce risks associated with excessive estrogen stimulation (e.g., premenstrual syndrome, certain breast discomfort). Its potential anti-cancer effects are also based on this mechanism.

Perimenopause/Menopause

Sharply Declining

Estrogen-Like Effect (Supplementation/Mimicry)

Gently alleviates menopausal symptoms caused by estrogen deficiency (hot flashes, insomnia, mood swings), making it a popular choice for natural hormone replacement therapy.

Postmenopause

Consistently Low

Estrogen-Like Effect (Supplementation/Mimicry)

Continues to provide weak estrogenic effects, particularly in protecting bone density, preventing osteoporosis, and maintaining cardiovascular health.

Genistein Benefits

Regulating Estrogen Levels: Genistein's molecular structure is similar to that of human estrogen, enabling bidirectional regulation of estrogen activity. For menopausal women, it can slightly compensate for the decline in estrogen levels, helping to alleviate discomfort such as hot flashes and night sweats. For younger women, it can also competitively occupy estrogen receptors, potentially reducing some of the risks associated with high estrogen levels.

Protecting Cardiovascular Health: Studies have shown that genistein helps lower low-density lipoprotein (LDL), improve endothelial function, and inhibit abnormal platelet aggregation, thereby playing a positive role in preventing atherosclerosis and cardiovascular disease.

Antioxidant and Anti-inflammatory: Genistein is a powerful antioxidant that effectively scavenges free radicals in the body and reduces cellular damage caused by oxidative stress. It also inhibits the production of various pro-inflammatory factors, exhibiting excellent anti-inflammatory properties, which may help delay aging and prevent chronic diseases.

Supporting Bone Health: Through its estrogen-like effects, genistein can help reduce bone loss and promote osteoblast activity, playing an important role in maintaining bone density and preventing osteoporosis.

Potential anti-cancer properties: A large number of basic studies have shown that genistein can inhibit the proliferation of various cancer cells, induce cancer cell apoptosis, and inhibit the formation of new tumor blood vessels. It has been widely explored in the fields of breast cancer and prostate cancer, but its actual preventive and therapeutic effects still need more clinical evidence to support.

FUNCTIONS

Genistein Uses
Pharmaceutical and Health Products Industry

This is genistein's core application area. Leveraging its phytoestrogen properties, it is widely used in the development of health supplements and pharmaceuticals to alleviate menopausal symptoms in women, such as hot flashes and insomnia. Furthermore, based on research on its antioxidant, bone-building, and potential anti-cancer activities, it is also being formulated into dietary supplements or pharmaceutical ingredients for preventing osteoporosis, supporting cardiovascular health, and assisting in cancer treatment.

Functional Food and Beverage Industry

As a natural functional factor, genistein is extensively added to various foods and beverages to create high-value-added products. Common applications include fortified soy protein beverages, nutritional bars, meal replacements, and dairy products specifically formulated for women's health. These products promote a "natural and healthy" concept, addressing consumer demand for chronic disease prevention and healthy aging.

 Cosmetics and Personal Care Industry

Due to its potent antioxidant and anti-inflammatory properties, genistein has become a popular active ingredient in high-end skincare products. It can effectively neutralize free radicals, delay skin photoaging, and reduce UV damage; at the same time, its estrogen-like effect is believed to promote collagen production, improve skin elasticity, and reduce wrinkles. It is often used in essences, creams and other products for anti-aging, whitening and soothing sensitive skin.

Genistein Uses

Side Effects of Genistein

Genistein, an isoflavone extracted from plants such as soybeans and kudzu root, is a phytoestrogen. It is commonly found in many health supplements and foods, primarily used to alleviate menopausal symptoms and prevent osteoporosis. Its side effects are primarily related to its estrogen-like activity.These side effects are generally dose-related and less common with a normal diet or low-dose supplementation, but may occur with high-dose supplementation.

  • Gastrointestinal Distress:These include nausea, bloating, loss of appetite, constipation, or diarrhea. These are common side effects associated with many dietary supplements.
  • For women: These may cause menstrual cycle changes, menstrual discomfort, breast tenderness, and endometrial hyperplasia. These effects may be less pronounced in postmenopausal women.
  • For men: High doses may theoretically cause minor effects on hormone levels, such as lowering testosterone levels, but research results are inconsistent. In most healthy men, these effects are minimal with a normal diet or standard supplementation doses.
Why Choose Kintai?

kintai

  • ​​​​​​Improve product competitiveness: High-quality, standardized genistein extracts add unique benefits to your products and enhance market competitiveness.
  • Shorten the R&D cycle: We provide detailed product info and technical support to help you quickly complete product development,seize market opportunities.
  • Stable supply chain: With a stable supply of raw materials and production capacity, we ensure stable supply and reasonable prices in long-term cooperation.

As a leading genistein supplier, Kintai ensures GMP-certified production and global compliance for reliable bulk sourcing.Kintai's genistein supports men's health by promoting prostate wellness and antioxidant protection.Among top genistein manufacturers, Kintai stands out for its strict quality control and batch-to-batch consistency.Kintai operates a state-of-the-art Genistein powder factory with ISO, HALAL, and KOSHER certifications for global distribution.

FAQ

Q: Is it right for utilization?

A: Indeed, our item is gotten from regular sources and is okay for utilization. Notwithstanding, counseling a medical services proficient prior to beginning any new supplement is consistently prudent.

Q: How fast is the delivery of your product?

A: We prioritize fast delivery, ensuring your products reach you instantly without compromising quality.

Q: Are you a certified manufacturer?

A: Yes, Kintai is a professional Genistein manufacturer and supplier. We have a dedicated research and development center, production base, and advanced equipment. We have different licenses and affirmations to guarantee the best norms are met.

Assuming that you are searching for Genistein, please contact us at info@kintaibio.com. We are your believed accomplice in accomplishing your well-being and health objectives.​​​​​​​

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