Genistein Powder
Extract Source:100% Natural
Origin:China
Specification: 98% Isoflavones Genistein (Other specifications can be customized)
Appearance: Off Yellow powder
CAS No: 446-72-0
Test Method: HPLC
Lead time: 1-3 days
Shelf Life: 2 years
Sample: Free sample available
Content: Natural, Non-GMO, Non-additive
Applications:Health Care Products, Medicine, Cosmetics
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Payment: Multiple terms acceptable like T/T, L/C, DA
Storage: Store in a well-closed container away from moisture and direct sunlight.Keep in cool dry place
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Genistein Powder Manufaturer and Supplier
Genistein powder, a natural isoflavone primarily derived from leguminous plants, exhibits a broad spectrum of pharmacological activities and is often referred to as a "natural phytoestrogen". It is predominantly found in species such as the pagoda tree (Sophora japonica) and is abundantly distributed across multiple regions of China, including Henan, Tianjin, Hebei, Shandong, and Shaanxi.
Xi'an Kintai Biotechnology Co., Ltd. is a professional plant extract manufacturer. We are committed to providing our customers with high-quality genistein raw materials, helping them create innovative products that align with market trends. Currently, genistein is widely used in medicine, health supplements, and cosmetics. Its significant anti-cancer, anti-aging, antioxidant, and anti-osteoporosis benefits make it a highly sought-after core ingredient in the healthcare industry. Choose Kintai and let us empower your brand value and market competitiveness with our high-quality raw materials and professional support.
KINTAI's Genistein Powder Advantages
- High purity and standardization: The advanced extraction process ensures that the purity of genistein is as high as 98% or more, which meets the international GMP and ISO standards, and provides excellent quality assurance for your products.
- Natural source, safe and effective: Select high-quality plant raw materials, no chemical additives throughout the process, to ensure that the product is natural, pure, safe and effective, in line with the global market demand for green and healthy products.
- Significant biological activity: After strict quality control and scientific verification, genistein powder shows excellent antioxidant, anti-inflammatory and other biological activities, adding unique selling points to your products.
Flexible customization to meet needs: Provide a full range of customized services from raw material selection to product specifications and packaging to ensure that your products are unique and meet specific market needs.
KINTAI Genistein Powder COA
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Genistein Powder Quality Specification&Standard
ProductName |
GenisteinPowder |
Extraction source |
Fabaceae Genista (Gorse) |
Assay |
98% |
Appearance |
Off Yellow powder |
Solubility |
Soluble in commonly used organic solvents, almost insoluble in water, soluble in dilute alkali |
Extract Solvent |
Ethanol |
Loss on Drying |
NMT2.0% |
Pb |
NMT1ppm |
As |
NMT1ppm |
Hg |
NMT0.1ppm |
Cd |
NMT1ppm |
Total Plate Count |
NMT1000cfu/g |
Total Yeast & Mold |
NMT100cfu/g |
Storage conditions |
Preserve in tight containers at a Cool & dry place.(2℃--- 8℃) Keep away from strong light and heat. |
Chromatogram of Kintai Genistein
Chemical&Physical Properties of Genistein
Property |
Description |
Chemical Name |
4',5,7-Trihydroxyisoflavone |
Synonyms |
Genistein, Genisteol, Prunetol |
CAS Number |
446-72-0 |
Molecular Formula |
C₁₅H₁₀O₅ |
Molecular Weight |
270.24 g/mol |
Appearance |
Off-white to pale yellow crystalline powder |
Melting Point |
297 °C - 298 °C (decomposition) |
Solubility |
Soluble in: DMSO, DMF, ethanol, methanol. |
pKa Values |
~7.2 (phenolic hydroxyl group), ~9.9 (phenolic hydroxyl group) |
Log P (Octanol-Water Partition Coefficient) |
~2.5 - 3.1 (Indicates lipophilicity) |
UV-Vis Absorption (λmax) |
~259 - 261 nm (shoulder), ~330 nm (in methanol) |
Stability |
Stable under recommended storage conditions. Sensitive to light and oxygen. Solutions are stable for up to 24 hours at 2-8°C. |
Kintai Genistein Raw Material and Production Process flow
Raw Material of Kintai Genistein
Genistein (5,7,4'-trihydroxyisoflavone) is a naturally occurring isoflavone abundant in leguminous plants, with a particularly high concentration in the fruits of Sophora japonica L. (pagoda tree). This plant has long been recognized in traditional Chinese medicine for its medicinal properties. It contains various flavonoids and isoflavones, among which genistein serves as a major active constituent. In its natural state, genistein primarily exists in glycosidic form within the plant matrix. The compound commonly referred to as genistein is actually the aglycone released through hydrolysis of these glycosides. Consequently, genistein powder is typically produced via extraction and subsequent hydrolysis of Sophora japonica L. raw materials.Kintai's genistein uses high-quality Sophora japonica fruit as raw material to produce standardized high-quality genistein for you.
Kintai genistein is presented as a light yellow crystalline powder with a high melting point of 297°C–298°C. It demonstrates excellent solubility in ethanol and DMSO, though it is sparingly soluble in water. A distinctive yellow color develops in dilute alkaline solution, making it well-suited for incorporation into a variety of health supplement formulations. To accommodate diverse application requirements, we offer two standard grades: HPLC 98% methanol-extracted and ethanol-extracted Genistein, ensuring flexibility for our customers' specific uses.
Production process flow
Raw Material Collection: Starting with the extraction of Sophoricoside from the plant source.
Hydrolysis Process: Using ethanol to hydrolyze Sophoricoside into high-purity Genistein.
Refining & Testing: Involving multiple refinement and quality control checks to ensure the final product meets the required standards.
Genistein for Women Health
The effect of genistein on female hormones is not a single 'supplementation' or 'antagonism', but an 'bidirectional'regulation, and its ultimate effect depends on the woman's own physiological state and hormone levels.
Physiological Stage |
Endogenous Estrogen Level |
Endogenous Estrogen Level |
Impact on Women |
|
Reproductive Age |
High |
Anti-Estrogenic Effect (Competition/Inhibition) |
May help balance hormone levels and reduce risks associated with excessive estrogen stimulation (e.g., premenstrual syndrome, certain breast discomfort). Its potential anti-cancer effects are also based on this mechanism. |
|
Perimenopause/Menopause |
Sharply Declining |
Estrogen-Like Effect (Supplementation/Mimicry) |
Gently alleviates menopausal symptoms caused by estrogen deficiency (hot flashes, insomnia, mood swings), making it a popular choice for natural hormone replacement therapy. |
|
Postmenopause |
Consistently Low |
Estrogen-Like Effect (Supplementation/Mimicry) |
Continues to provide weak estrogenic effects, particularly in protecting bone density, preventing osteoporosis, and maintaining cardiovascular health. |
Products Functions of Genistein
Regulating Estrogen Levels: Genistein's molecular structure is similar to that of human estrogen, enabling bidirectional regulation of estrogen activity. For menopausal women, it can slightly compensate for the decline in estrogen levels, helping to alleviate discomfort such as hot flashes and night sweats. For younger women, it can also competitively occupy estrogen receptors, potentially reducing some of the risks associated with high estrogen levels.
Protecting Cardiovascular Health: Studies have shown that genistein helps lower low-density lipoprotein (LDL), improve endothelial function, and inhibit abnormal platelet aggregation, thereby playing a positive role in preventing atherosclerosis and cardiovascular disease.
Antioxidant and Anti-inflammatory: Genistein is a powerful antioxidant that effectively scavenges free radicals in the body and reduces cellular damage caused by oxidative stress. It also inhibits the production of various pro-inflammatory factors, exhibiting excellent anti-inflammatory properties, which may help delay aging and prevent chronic diseases.
Supporting Bone Health: Through its estrogen-like effects, genistein can help reduce bone loss and promote osteoblast activity, playing an important role in maintaining bone density and preventing osteoporosis.
Potential anti-cancer properties: A large number of basic studies have shown that genistein can inhibit the proliferation of various cancer cells, induce cancer cell apoptosis, and inhibit the formation of new tumor blood vessels. It has been widely explored in the fields of breast cancer and prostate cancer, but its actual preventive and therapeutic effects still need more clinical evidence to support.
Applications of Genistein
Pharmaceutical and Health Products Industry
This is genistein's core application area. Leveraging its phytoestrogen properties, it is widely used in the development of health supplements and pharmaceuticals to alleviate menopausal symptoms in women, such as hot flashes and insomnia. Furthermore, based on research on its antioxidant, bone-building, and potential anti-cancer activities, it is also being formulated into dietary supplements or pharmaceutical ingredients for preventing osteoporosis, supporting cardiovascular health, and assisting in cancer treatment.
Functional Food and Beverage Industry
As a natural functional factor, genistein is extensively added to various foods and beverages to create high-value-added products. Common applications include fortified soy protein beverages, nutritional bars, meal replacements, and dairy products specifically formulated for women's health. These products promote a "natural and healthy" concept, addressing consumer demand for chronic disease prevention and healthy aging.
Cosmetics and Personal Care Industry
Due to its potent antioxidant and anti-inflammatory properties, genistein has become a popular active ingredient in high-end skincare products. It can effectively neutralize free radicals, delay skin photoaging, and reduce UV damage; at the same time, its estrogen-like effect is believed to promote collagen production, improve skin elasticity, and reduce wrinkles. It is often used in essences, creams and other products for anti-aging, whitening and soothing sensitive skin.
Genistein powder Market Share
Product Examples and Usage Dosages
Dietary Supplements: Companies like Now Foods, Nature's Way, Garden of Life, Solgar, GNC, Herbalife, Puritan's Pride, Swanson, Life Extension, and Jarrow Formulas offer Genistein Powder as a dietary supplement. The dosage typically ranges from 50 to 200 mg per serving, with some products containing up to 500 mg per serving.
Functional Foods: In 1994, Nutritious Foods, Inc., a subsidiary of Protein Technologies International, launched Altima HP-20 Nutritious Beverage Powder, which contains 20 mg of genistein per 8-ounce serving, and Altima FA-8 Nutritious Beverage Powder, which contains 8 mg of genistein per 8-ounce serving.
Cosmetics: In August 2022, Paula's Choice introduced the CLINICAL Phytoestrogen Elasticity Renewal Body Treatment and CLINICAL Phytoestrogen Elasticity Renewal Serum, which use genistein as one of the three phytoestrogens. In March 2022, OneSkin launched the OS-01 Topical Supplement BODY, a skin longevity supplement that combines the OS-01 peptide with ingredients such as ceramides, phytochemical sulforaphane, sporocarp mushroom extract, and genistein.
Pharmaceuticals: Hologram Sciences introduced a women's health brand concept called Phenology in May 2022, which uses DSM's GeniVida genistein to treat hot flashes.
Why Choose Kintai
- Improve product competitiveness: High-quality, standardized genistein extracts add unique benefits to your products and enhance market competitiveness.
- Shorten the R&D cycle: We provide detailed product info and technical support to help you quickly complete product development,seize market opportunities.
- Stable supply chain: With a stable supply of raw materials and production capacity, we ensure stable supply and reasonable prices in long-term cooperation.
As a leading genistein supplier, Kintai ensures GMP-certified production and global compliance for reliable bulk sourcing.Kintai's genistein supports men's health by promoting prostate wellness and antioxidant protection.Among top genistein manufacturers, Kintai stands out for its strict quality control and batch-to-batch consistency.Kintai operates a state-of-the-art Genistein powder factory with ISO, HALAL, and KOSHER certifications for global distribution.
FAQ
Q: Is it right for utilization?
A: Indeed, our item is gotten from regular sources and is okay for utilization. Notwithstanding, counseling a medical services proficient prior to beginning any new supplement is consistently prudent.
Q: How fast is the delivery of your product?
A: We prioritize fast delivery, ensuring your products reach you instantly without compromising quality.
Q: Are you a certified manufacturer?
A: Yes, Kintai is a professional Genistein manufacturer and supplier. We have a dedicated research and development center, production base, and advanced equipment. We have different licenses and affirmations to guarantee the best norms are met.
Assuming that you are searching for Genistein, please contact us at info@kintaibio.com. We are your believed accomplice in accomplishing your well-being and health objectives.
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