Carob Bean Extract D-Chiro-Inositol(DCI) Powder

Carob Bean Extract D-Chiro-Inositol(DCI) Powder Manufacturer

Healthkintai^® is a leading Chinese manufacturer of Carob Extract D-Chiro-Inositol(DCI) Powder. The following are our current product specifications:

DCI from carob bean extract is a natural active component of the inositol family, primarily extracted from carob grown in the Mediterranean region, so Ceratonia siliqua carob fruit extract and Ceratonia siliqua fruit extract are also its common name. It is not a traditional Chinese medicine but has gained attention in modern nutrition and metabolic research, particularly for improving insulin resistance and Polycystic Ovary Syndrome (PCOS).

If you require high-quality D-Chiro-Inositol(DCI) Powder, please feel free to contact us at health@kintaibio.com. 

The Certificate of Analysis of Carob Bean Extract D-Chiro-Inositol(DCI) Powder

Regulatory Status of Carob Bean Extract D-Chiro-Inositol(DCI) 

D-Chiro-Inositol (DCI) derived from carob bean extract is legally available in major markets as a dietary supplement, but specific regulations vary.

United States

The FDA considers DCI a legal dietary supplement ingredient.

European Union

The European Commission has declared that D-chiro-inositol is not a “novel food”, making it permissible for use in food supplements across all EU member states. This decision clarifies a previous regulatory uncertainty in some countries, and companies can use it without further authorization problems.

Canada

Health Canada permits the use of D-chiro-inositol in natural health products.

Australia

The Therapeutic Goods Administration (TGA) allows DCI to be used in complementary medicines.

Carob Bean Extract D-Chiro-Inositol(DCI) Powder Botanical Source

The “carob” used as the source of our DCI Powder specifically refers to the Mediterranean carob tree. Its pods are sweet and are often ground into powder as a substitute for cocoa or chocolate. It is not the Chinese honey locust found in traditional Chinese medicine.

Why We Choose Carob

 Carob contains a relatively high concentration of DCI, making it an ideal raw material for commercial extraction. Research data indicates that the DCI content in its extract can reach approximately 40g/kg.

Other Plant Sources

DCI also occurs naturally in plants such as buckwheat and soybeans, but typically in lower concentrations than in carob. Therefore, most high-purity DCI supplements on the market are extracted from carob.

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Note: To meet the demand for high-purity D-chiro-inositol, we also offer synthetically produced D-chiro-inositol.

The Benefits of Carob Bean Extract D-Chiro-Inositol(DCI)

Relationship between D-Chiro-Inositol(DCI) and Myo-Inositol(MI)

DCI is produced from MI in the body through an enzyme-driven conversion. While MI makes up the majority of inositols in the body, DCI has its own distinct functions, particularly in insulin signaling. Many supplements combine both forms to provide a more comprehensive approach to benefits like hormonal balance and fertility support.

MI and DCI are the two most important biologically active stereoisomers within the inositol family. They are not interchangeable but function as synergistic and complementary “partners” within the body, working together to maintain insulin signaling and metabolic balance.​​​​​​​

Research indicates that supplementation mimicking the average physiological ratio found in human plasma (MI to DCI ratio of approximately 40:1) can most effectively lead to comprehensive improvement in metabolic parameters, hormone levels, and ovulatory function in PCOS patients, with a high safety profile.

Core Efficacy of DCI: Regulating Insulin Sensitivity and Improving Metabolic Disorders

The inositol family serves as a key regulatory factor in the insulin signaling pathway. DCI can enhance the efficiency of post-insulin receptor signal transduction and reduce cellular insulin resistance. It can assist in improving blood glucose control in patients with prediabetes or mild type 2 diabetes, reduce fasting/postprandial insulin levels, and lower the risk of hyperinsulinemia. It can alleviate insulin resistance-related dyslipidemia. And it also has an auxiliary regulatory effect on metabolic syndrome (e.g., abdominal obesity, mild elevation of blood pressure).

Key Application of DCI: Ameliorating Symptoms Associated with Polycystic Ovary Syndrome (PCOS)

DCI is a crucial nutrient for clinical adjuvant intervention in PCOS, exerting its effects by modulating the insulin-androgen axis:Reducing the luteinizing hormone (LH)/follicle-stimulating hormone (FSH) ratio in PCOS patients, decreasing ovarian androgen (testosterone) secretion, and alleviating hyperandrogenic manifestations such as hirsutism, acne, and seborrheic dermatitis; Restoring the ovarian ovulatory rhythm, increasing the ovulation rate, and aiding in improving fertility in PCOS patients; Compared with conventional inositol, DCI exhibits better targeting and dose adaptability in ameliorating insulin resistance and hyperandrogenemia in PCOS patients.

Other Potential Efficacies

Auxiliary regulation of idiopathic ovulatory dysfunction: For women with irregular ovulation not caused by PCOS, DCI can assist in restoring ovulatory rhythm by improving the metabolic microenvironment, though individualized assessment is required;

Auxiliary effect on gestational metabolism: Some studies indicate that rational supplementation may reduce the risk of gestational insulin resistance, yet pregnant women must strictly follow medical advice and must not take it without authorization.

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The Uses of Carob Bean Extract D-Chiro-Inositol(DCI) Powder

Our DCI powder is Versatile in applications.

Being used to make capsules and tablets

It can serve as a raw material for health supplements for managing metabolic syndrome, PCOS, and diabetes.

Being added to foods

It can be added to beverages, dairy products or baked goods to boost nutritional value and improve product texture and stability.

Being added to cosmetic

It can be put into high-end cosmetics to leverage its antioxidant and anti-aging properties.

The Side Effects of Carob Bean Extract D-Chiro-Inositol(DCI)

Most individuals do not appear to experience any side effects when taking myo-inositol and DCI at appropriate dosages. However, as with any supplement, women with polycystic ovary syndrome (PCOS) may experience mild side effects when taking inositol, which are usually reported with high-dose intake.

A study involving more than 250 patients found that myo-inositol taken at doses of 12–30 grams per day was associated with gastrointestinal side effects such as nausea and stomach pain. It is worth noting, however, that this is a high dose—more than three times the recommended amount—and the recommended dosage is much lower than this.

Why Should You Choose HealthkintaiR to Buy Carob Bean Extract D-Chiro-Inositol(DCI) Powder?

As a professional foreign trade enterprise with 10 years of experience in the international trade of botanical extracts and pharmaceutical intermediates, Healthkintai^® is committed to providing high-quality DCI powder that stands out in the global market.

Choosing our DCI powder means partnering with a reliable expert in the health industry. We are dedicated to upholding the principle of “quality first, customer foremost” and providing comprehensive support from product supply to after-sales service, empowering your success in the global health industry.

Contact us now at health@kintaibio.com to obtain samples and detailed quotes, and experience the exceptional quality of DCI powder from Healthkintai^®!

FAQ

1. Can DCI improve egg quality?

DCI alone can worsen egg quality in some cases, while a combination of MI and DCI in a 40:1 ratio may improve it. High doses of DCI have been associated with a decrease in mature oocytes and quality embryos, while the balanced ratio may mimic the body’s natural inositol levels, supporting egg quality.

2. How long does it take for D-chiro inositol to work?

It can take three to six months of consistent use to see noticeable benefits from DCI, although some individuals may notice effects sooner or later. Studies have shown significant improvements in certain markers like blood sugar, insulin levels, and hormones after six months of treatment. 

3. Is inositol safe for pregnancy?

Inositol is possibly safe for short-term use in pregnancy, particularly when taken with folic acid to potentially prevent gestational diabetes, but you must consult a healthcare provider before taking it.

 Studies have shown doses up to 4 grams of MI per day are well-tolerated with no adverse effects reported. However, more research is needed for long-term use and during breastfeeding.