Broccoli Seed Extract

Broccoli Seed Extract manufacturer and Supplier

Broccoli extract is primarily derived from the seeds and shoots, with its core components being sulforaphane and its active metabolite, sulforaphane. Sulforaphane is a potent Nrf2 pathway activator, significantly enhancing the body's antioxidant and detoxification capabilities, possessing anti-inflammatory and anti-cancer potential, and supporting cardiovascular and neurological health.

Xi'an Healthkintai^® is a leading producer of Broccoli Seed Extract and glucosinolates in China. Leveraging our unique cultivation and extraction technologies, we provide high-quality raw materials to customers worldwide. If you require 0.6%-30% Sulforaphane & Glucosinolate, please feel free to contact us at info@kintaibio.com.

Kintai's Broccoli seed extract specifications

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Broccoli seed extract Physical and Chemical Properties

Broccoli seed extract Benefits

1. Powerful Antioxidant and Cell Protection

Its effects go far beyond simply neutralizing free radicals. The core mechanism of sulforaphane lies in activating the Nrf2 (nuclear factor E2-related factor 2) signaling pathway within cells. This pathway is known as the "master switch" of cellular defense; once activated, it can initiate the expression of over 200 protective genes and systematically enhance the synthesis of various endogenous antioxidant enzymes, including glutathione and superoxide dismutase (SOD). This is equivalent to strengthening the body's own "antioxidant defense system," thereby fundamentally enhancing the cell's ability to resist oxidative stress and exogenous damage such as environmental pollution and radiation, achieving deep-level cell protection.

2. Anti-inflammatory Effects Through Multiple Mechanisms

Chronic low-grade inflammation is a common underlying condition for many chronic diseases. Sulforaphane can effectively reduce the production of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) by inhibiting the overactivation of key inflammatory signaling pathways such as NF-κB (nuclear factor κB). This regulatory effect on inflammatory responses helps alleviate persistent inflammatory states associated with arthritis, metabolic syndrome, cardiovascular disease, and even neurodegenerative diseases, providing adjunctive support for chronic disease management.

3. Clear Chemoprevention and Anti-cancer Potential

Its anti-cancer properties are manifested in multiple stages of cancer development. In the initial stage, it can promote the detoxification and excretion of carcinogens; in the promotion stage, it can selectively inhibit the growth of precancerous and cancerous cells by regulating the cell cycle and inducing apoptosis; in the progression stage, it can also inhibit tumor angiogenesis, cutting off its nutrient supply. Numerous preclinical studies have confirmed its particularly prominent chemopreventive effects on gastrointestinal tumors such as gastric and colorectal cancer, making it a hot topic in tumor nutritional intervention research.

4. Neurological and Metabolic Health Support

With its powerful anti-inflammatory and antioxidant capabilities, sulforaphane can cross the blood-brain barrier, protecting neurons from oxidative damage and promoting the expression of brain-derived neurotrophic factor (BDNF), showing potential for improvement in models of neurodegenerative diseases such as Alzheimer's and Parkinson's. At the same time, it can also have a positive impact on blood glucose and blood lipid levels by improving insulin sensitivity and regulating lipid metabolism, thereby providing synergistic support for the prevention and control of metabolic diseases such as diabetes, fatty liver and atherosclerosis.

Broccoli extract Uses

1. Broccoli Extract Supplements

This is the most important and mature application area. Extracts are often formulated into capsules, tablets, or powders as daily dietary broccoli seed extract supplement​
to enhance antioxidant, anti-inflammatory, and detoxification functions. They are also added to medical foods, solid beverages, and functional drinks to meet specific health needs.

2. Broccoli Extract for Skincare and Cosmetics

Based on its excellent antioxidant and anti-inflammatory properties, broccoli extract is highly favored in the skincare market. It effectively combats oxidative damage caused by environmental factors such as ultraviolet radiation, reduces skin inflammation, and is used in anti-aging, soothing, repairing, and brightening serums and creams.

3. Animal Nutrition and Health

In the livestock and pet food sector, as a natural plant-based additive, it is used to enhance animal immunity, improve gut health, reduce oxidative stress, and may reduce antibiotic use, aligning with the development trend of "antibiotic-free farming" and healthy pet food.And their active ingredients can serve as natural plant growth regulators or biostimulants, helping crops resist biotic and abiotic stresses (such as diseases and drought), improving crop quality and yield, and are potential inputs for green agriculture.

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Broccoli  Seed Extract ​​​​​​​Dosage​​​​​​​

Currently, major global regulatory agencies, such as the U.S. Food and Drug Administration (FDA), have not established a uniform, officially recommended daily dosage (RDI) for broccoli extract or sulforaphane. This is primarily because of its status as a dietary supplement rather than an essential nutrient. However, existing dosage recommendations are mainly based on published preclinical and clinical studies.

In scientific research, the commonly used and considered safe effective dosage range, in terms of sulforaphane, is typically between 20 and 40 mg per day. Certain specific studies (such as in the field of autism or assistive therapy for specific diseases) may use higher dosages (e.g., above 100 mg per day), but this must be conducted under the guidance of a medical professional. Studies by the U.S. Department of Agriculture (USDA) and the European Food Safety Authority (EFSA) provide important scientific references for these dosage ranges, but neither has established them as regulatory standards.

Side Effects of Broccoli  Seed Extract

Broccoli extract is generally considered safe at recommended doses, but excessive intake or in unsuitable individuals may still cause side effects, primarily due to its potent biological activity.

The most common side effects are mild gastrointestinal discomfort, such as bloating, stomach upset, or diarrhea, which may be related to the irritation of the digestive tract by high concentrations of the active ingredient. Secondly, because sulforaphane can significantly enhance the activity of liver detoxification enzymes, it may theoretically accelerate the metabolism of certain drugs (such as analgesics and chemotherapy drugs) in the body, thus affecting their efficacy; caution should be exercised and a doctor consulted during use.

In rare cases, allergic reactions may occur. Due to its potent mechanism of action, it is recommended that pregnant women, breastfeeding women, and individuals with thyroid dysfunction avoid use in the absence of clear safety data. Overall, choosing standardized products and adhering to recommended dosages is crucial.

Why Choose KINTAI?

• Deeply Customizable

We not only offer standardized 0.6%-30% Sulforaphane & Glucosinolate, but also provide flexible customized solutions based on your formulation needs (such as complex ingredients or specific solvent systems), precisely matching your product development goals.

• Stringent International Certifications

Our production system is certified by authoritative bodies such as GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL to ensuring the safety, compliance, and unimpeded access to the global market for our raw materials, thus endorsing your brand.

• Years of Professional Experience

As one of the earliest companies in China to deeply cultivate this field, we possess experience in controlling the entire supply chain from exclusive cultivation to efficient extraction. Our mature and stable technology continuously guarantees high purity, high activity, and batch-to-batch consistency of our products, making us a trustworthy long-term partner.Please feel free to contact us at info@kintaibio.com.

FAQ​​​​​​​

Q1:Does broccoli extract lower estrogen?

A1:Current research evidence is insufficient and inconclusive. Some cell and animal studies have found that sulforaphane, a key component of broccoli extract, may potentially affect estrogen levels by regulating estrogen-metabolizing enzymes, such as promoting its conversion to safer metabolic forms. However, human clinical studies are very limited, and its efficacy and safety have not yet been established.

Q2:Is sulforaphane safe for kidneys?

A2:In general, sulforaphane is considered safe for the kidneys at appropriate dietary or supplemental doses. In fact, numerous studies highlight its protective effects on renal health, primarily due to its potent antioxidant and anti-inflammatory properties. It can help alleviate kidney injury caused by oxidative stress, toxins, or certain medications.

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