L-rhamnose Monohydrate Powder

Sophora Japonica Extract L-rhamnose Manufacturer and Supplier

Sophora Japonica Extract L-rhamnose is an active ingredient extracted from the flowers of Sophora japonica L., with L-rhamnose, a natural sugar, as its core component.It is renowned for its excellent moisturizing and anti-aging effects, promoting the synthesis of hyaluronic acid in the skin and strengthening its barrier function, and is widely used in high-end skincare products. It also possesses antioxidant and anti-inflammatory properties and can act as a prebiotic to regulate gut health. This extract combines traditional Chinese medicine wisdom with modern biotechnology, representing a prime example of natural functional ingredients.

Healthkintai^® 99% L-rhamnose monohydrate is extracted from Sophora Japonica. We maintain strict control from the very beginning of raw material selection and can provide you with customized services. Please feel free to contact us at info@kintaibio.com.

KINTAI L-rhamnose Specifications

Physicochemical Properties of L-Rhamnose Monohydrate

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Benefits of L-Rhamnose

1. L-Rhamnose as a Sweetener

L-Rhamnose plays multiple roles in food flavor, going far beyond simply providing sweetness. It imparts a refreshing and mellow sweetness to food while effectively neutralizing the metallic or bitter aftertastes of artificial sweeteners. More importantly, rhamnose is an excellent flavor enhancer, significantly enhancing and highlighting the natural fruit aromas of fruits such as strawberries and peaches, and harmonizing a richer creamy aroma in dairy products. During processing, it also participates in caramelization, producing a pleasant roasted aroma and softening sharp acidity in products, resulting in a more rounded and balanced overall flavor. Therefore, rhamnose is a high-value food ingredient that optimizes flavor profiles and enhances the naturalness and harmony of the taste.

2.L-Rhamnose for Skin

L-Rhamnose has been approved by the European Union's EFSA as a safe cosmetic ingredient, with the concentration determined by the manufacturer's safety assessment.L-Rhamnose demonstrates remarkable moisturizing and barrier-repairing effects in the field of skin health. As a highly effective bioactive molecule, it precisely targets skin cells, promoting the synthesis of key proteins.

On one hand, Rhamnose Sugar powder significantly upregulates the expression of aquaporin 3 in keratinocytes, effectively opening water channels from within, thereby enhancing the skin's own water-holding and moisturizing abilities and fundamentally alleviating dryness. On the other hand, it effectively promotes the production of tight junction proteins (such as Claudin-1), acting like strengthening the cement in a brick wall, significantly enhancing the physical barrier function of the skin's outermost layer, reducing internal moisture loss, and effectively resisting the invasion of external irritants, allergens, and microorganisms. This dual mechanism makes it a core ingredient in high-end anti-allergy, repairing, and anti-aging skincare products.

3.L-Rhamnose Regulates Gut Function

It acts as a prebiotic, regulating gut microbiota and supporting immune health. When ingested, L-rhamnose monohydrate is not digested in the upper digestive tract, reaching the colon intact and being selectively utilized by beneficial bacteria such as Bifidobacteria, promoting their proliferation. This helps optimize the gut microbiota balance, inhibits the colonization of pathogenic bacteria, and thus improves gut function, positively impacting the relief of diarrhea or constipation. More importantly, this gut microbiota regulation is closely linked to the immune system. By promoting beneficial bacteria metabolism and strengthening the intestinal barrier, L-rhamnose can indirectly regulate systemic immune responses, helping to reduce unnecessary inflammation and providing the body with an internal immune support defense.

L-Rhamnose Uses

1.L-Rhamnose in Food Industry

L-Rhamnose demonstrates unique value as a sweetener beyond simply providing sweetness. While its sweetness is only 33% that of sucrose, it offers a refreshing and pure taste, effectively neutralizing the metallic or bitter aftertastes common in artificial sweeteners, thus significantly enhancing the overall flavor harmony. More importantly, it is a highly effective "flavor enhancer," amplifying and modifying the natural fruity aromas of strawberries, peaches, and other fruits, while bringing out a richer, creamier aroma in dairy products, resulting in a near-natural, full-bodied flavor experience in low-calorie foods.

2.L-Rhamnose in Cosmetics and Skincare

In the cosmetics and skincare industry, L-Rhamnose has become a key bioactive ingredient. Its core mechanism lies in its ability to deeply penetrate skin cells, enhancing deep hydration by promoting hyaluronic acid synthesis, and strengthening the skin's physical barrier by upregulating the expression of tight junction proteins. This makes it irreplaceable in anti-allergy, soothing, deep repair, and anti-glycation/anti-aging products, achieving a fundamental improvement in skin health rather than a temporary masking effect.

3.L-rhamnose in Pharmaceutical field

In the fields of medicine and biotechnology, Rhamnose Sugar powder its molecular value. It is a key chiral intermediate in the synthesis of anti-influenza drugs such as oseltamivir, playing a crucial role in medicinal chemistry. Simultaneously, as a highly selective prebiotic, it effectively promotes the proliferation of beneficial bacteria such as Bifidobacteria in the gut, regulating gut microbiota balance and supporting immune health. Furthermore, based on its recognition of specific receptors, it is also being explored as a "navigation head" for targeted drug delivery systems, showing great promise.

Dosage of L-rhamnose

Side Effects of L-Rhamnose

L-Rhamnose is generally considered a safe substance, but its side effects are primarily related to dosage and individual variability. The most common adverse reactions are gastrointestinal. At higher oral doses (e.g., exceeding several grams at a single dose), some individuals may experience mild digestive discomfort such as bloating, flatulence, or diarrhea. This is mainly due to the fermentation of unabsorbed rhamnose by gut microbiota in the colon, producing gas. These symptoms are usually temporary and lessen as the body adapts or the dose is reduced.

Regarding topical application,L-rhamnose monohydrate as a cosmetic ingredient has extremely low irritation at normal concentrations (typically 0.1%-3%), with rare reports of allergies or skin discomfort. However, for extremely sensitive skin, a local skin test is still recommended. Overall, it has a good safety profile at appropriate dosages and methods of use, but it is recommended to start with a lower dose and observe individual responses.

Where to buy Best L-rhamnose Powder？

• Natural and Pure Source: Our 99%Rhamnose Sugar powder is made from carefully selected sustainable plant-based natural ingredients (locust flowers), with no chemical synthesis involved in the entire process, ensuring the product possesses clean label attributes and natural bioactivity.
• Multiple International Certifications Guaranteed: The product has passed authoritative certifications such as ISO, HACCP, Halal, and Kosher, providing a proven track record of safety and compliance.
• Flexible Customization: We support customization of purity (from food grade to pharmaceutical grade), particle size, packaging, and solubility characteristics to meet diverse application scenarios.Feel free to contact us at info@kintaibio.com.

​​​​​​​FAQ

Q1:What is the difference between L-Rhamnose and D-rhamnose?

A1:L-rhamnose and D-rhamnose are a pair of stereoisomers, their core difference lying in their spatial configurations. Specifically, the difference lies in the configuration of their chiral carbon atoms. They are mirror images of each other, like the left and right hands, and cannot be completely superimposed. This fundamental difference in configuration leads to significant differences in their biological activities, optical activity, and metabolic pathways.

Q2:Is rhamnose safe for skin?

A2:Our rhamnose powder is made from carefully selected sustainable plant-based ingredients, with no chemical synthesis involved in the entire process, ensuring the product meets clean label requirements and possesses natural bioactivity. It is a gentle and effective skincare ingredient. However, as with any cosmetic ingredient, a very small number of individuals with extremely sensitive skin may still react, therefore, a skin test is recommended before using any new product.

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