Apigenin Bulk Powder
Specification: 98% Apigenin
Appearance: Sticky yellow powder
CAS No: 520-36-5
Test Method: HPLC
Lead time: 1-3 days
Shelf Life: 2 years
Sample: Free sample available
Storage: Cool dry place and avoid light
Content: Vegan, Gluten-Free, Natural, Non-GMO, Non-additive
Certs: GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, HALAL
Company Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, Non-Irradiated/treat by heat only.
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Product Introduction
Product Details
What is Apigenin Bulk Powder?
Apigenin Bulk Powder is a kind of natural flavonoid which exists widely in many plants, especially in celery. It is a kind of natural antioxidant. It has been found that apigenin has the effects of lowering blood pressure, antiviral, anti-tumor, anti-oxidation, anti-inflammatory and sedation, among which its anti-tumor effect is the most prominent, and it can also inhibit the activity of melanocytes, so it is used in a variety of cosmetics.
Chemical & Physical Properties
CAS Number |
520-36-5 |
Density |
1.2319 (rough eatimate) |
Molecular Formula |
C15H10O5 |
Molecular Weight |
270.24 |
Melting Point |
>300 ℃ (lit.) |
Boiling Point |
333.35 ℃ (rough eatimate) |
Solubleness |
Dimethyl sulfoxide: 27 mg/ml |
Test Method |
HPLC |
Benefits of Apigenin Bulk Powder
Potent Antioxidant Properties
Apigenin, a natural flavonoid found in various plants such as chamomile, parsley, and celery, exhibits robust antioxidant capabilities that play a pivotal role in safeguarding cellular health. It works by neutralizing harmful free radicals—unstable molecules generated through metabolic processes or environmental stressors like pollution and UV radiation—that can damage DNA, proteins, and lipids. By scavenging these free radicals, apigenin reduces oxidative stress, a key driver of aging and chronic diseases. This protective action helps maintain cellular integrity, supports tissue repair, and may slow down age-related degenerative processes, making it a valuable component in formulations aimed at promoting overall wellness.
Powerful Anti-Inflammatory Effects
Beyond its antioxidant role, apigenin acts as a natural anti-inflammatory agent by modulating the body’s inflammatory pathways. It inhibits the production of pro-inflammatory cytokines (such as TNF-α and IL-6) and enzymes like cyclooxygenase (COX) and lipoxygenase (LOX), which are responsible for triggering inflammation. This dual action helps alleviate acute and chronic inflammatory responses in tissues, reducing redness, swelling, and pain associated with conditions like arthritis, dermatitis, and inflammatory bowel disease. Its ability to target inflammation at the molecular level makes it a promising candidate for natural remedies and pharmaceutical developments focused on managing inflammatory disorders.
Cardiovascular Health Support
Apigenin contributes significantly to cardiovascular wellness through multiple mechanisms. It promotes vasodilation by relaxing the smooth muscles of peripheral blood vessels, which reduces peripheral resistance and lowers cardiac afterload—ultimately supporting healthy blood pressure levels. Additionally, it enhances myocardial contractility, improving blood circulation and ensuring efficient oxygen and nutrient delivery to vital organs. Studies suggest it may also inhibit platelet aggregation, reducing the risk of blood clots, and help regulate cholesterol levels by preventing the oxidation of low-density lipoprotein (LDL), a key step in the development of atherosclerosis. Together, these effects make apigenin a valuable ally in preventing cardiovascular diseases and maintaining heart health.
Anticancer Potential
Emerging research highlights apigenin’s promising anticancer activity, attributed to its ability to interfere with multiple stages of tumor development. It inhibits the proliferation of cancer cells by inducing cell cycle arrest and promoting apoptosis (programmed cell death), particularly in breast, colon, lung, and prostate cancers. Furthermore, apigenin blocks the formation of new blood vessels that feed tumors (angiogenesis) and suppresses the migration and invasion of cancer cells, limiting metastasis. Its low toxicity to healthy cells compared to synthetic chemotherapeutic agents makes it an attractive candidate for adjuvant cancer therapies and preventive strategies.
Liver Protection
Apigenin supports liver health by mitigating liver damage and improving functional efficiency. It inhibits the accumulation of fat in hepatocytes (liver cells), reducing the risk of non-alcoholic fatty liver disease (NAFLD). Additionally, it enhances the activity of liver enzymes involved in detoxification, helping the liver eliminate harmful substances from the body. By reducing oxidative stress and inflammation in the liver, apigenin may also alleviate damage caused by toxins, alcohol, or certain medications, supporting long-term hepatic wellness.
Antibacterial and Antiviral Activity
Apigenin exhibits broad-spectrum antimicrobial properties, making it effective against various bacteria and viruses. It disrupts the cell membranes of pathogenic bacteria (such as Staphylococcus aureus and Escherichia coli) and inhibits their growth, while also interfering with viral replication cycles—including those of influenza, herpes simplex, and certain respiratory viruses. These properties position apigenin as a potential ingredient in natural antimicrobial formulations, from topical disinfectants to supplements aimed at boosting immune defenses against infectious diseases.
Mental Health Benefits: Anti-Anxiety and Antidepressant Effects
Apigenin has shown promise in supporting mental wellness by interacting with neurotransmitter systems in the brain. It binds to benzodiazepine receptors in the central nervous system, promoting the release of gamma-aminobutyric acid (GABA), a neurotransmitter that induces calmness and reduces anxiety. Additionally, it may regulate levels of serotonin and dopamine—key mood-regulating chemicals—helping to alleviate symptoms of depression and improve overall mood. These effects, combined with its low side-effect profile, make apigenin a natural candidate for supporting mental health in holistic wellness approaches.
Application Fields of Apigenin Bulk Powder
Medical Field: A Versatile Foundation for Therapeutic Development
Apigenin bulk powder serves as a critical raw material in pharmaceutical research and drug development, with its multifaceted biological activities making it a promising candidate for treating a range of diseases. In cardiovascular medicine, its ability to promote vasodilation, regulate blood pressure, and inhibit LDL oxidation supports the development of drugs targeting hypertension, atherosclerosis, and heart failure. For inflammatory conditions such as rheumatoid arthritis and inflammatory bowel disease, apigenin’s capacity to suppress pro-inflammatory cytokines (TNF-α, IL-6) and enzymes (COX, LOX) enables the creation of anti-inflammatory therapies with fewer side effects than traditional steroidal drugs.
In oncology, its anticancer properties—including induction of cancer cell apoptosis, inhibition of angiogenesis, and suppression of metastasis—make it a valuable component in adjuvant treatments for breast, colon, and lung cancers. Researchers are also exploring its potential in liver protective drugs, leveraging its ability to reduce hepatic fat accumulation and enhance detoxification enzymes to address non-alcoholic fatty liver disease (NAFLD) and drug-induced liver damage. Its broad-spectrum activity, combined with low toxicity to healthy cells, positions apigenin as a versatile building block for innovative, natural-origin pharmaceuticals.
Health Care Products: Harnessing Natural Wellness Benefits
As a natural flavonoid, apigenin bulk powder is widely integrated into health supplements, offering targeted support for overall wellness. Its potent antioxidant properties make it a key ingredient in anti-aging supplements, where it neutralizes free radicals to combat oxidative stress—slowing cellular aging and supporting skin, brain, and immune health. For individuals managing chronic inflammation, apigenin-based supplements help reduce systemic inflammation, alleviating symptoms of conditions like psoriasis and joint pain without the risks associated with long-term use of non-steroidal anti-inflammatory drugs (NSAIDs).
Hypertension-focused supplements often include apigenin to aid in maintaining healthy blood pressure levels through its vasodilatory effects, while liver support formulas leverage its ability to enhance hepatic detoxification and reduce fat buildup. Additionally, its mood-regulating properties—via GABA receptor activation and neurotransmitter balance—make it a popular addition to stress-relief and sleep-support supplements, offering a natural alternative to synthetic anxiolytics. These applications highlight apigenin’s role in bridging traditional natural medicine with modern wellness, catering to consumers seeking science-backed, gentle health support.
Food Field: Enhancing Nutritional Value and Shelf Life
Apigenin bulk powder is increasingly utilized as a functional food additive, enriching food products with both health benefits and preservative properties. As an antioxidant, it extends the shelf life of processed foods by inhibiting lipid oxidation—a major cause of spoilage in oils, snacks, and ready-to-eat meals—reducing the need for synthetic preservatives like BHT or BHA. In functional beverages (e.g., herbal teas, fruit juices) and fortified foods (cereals, energy bars), apigenin enhances nutritional profiles by adding anti-inflammatory and cellular protective benefits, aligning with consumer demand for “functional” foods that support wellness beyond basic nutrition.
Its natural origin also makes it suitable for clean-label products, appealing to health-conscious consumers seeking minimally processed ingredients. For example, apigenin-infused yogurt or plant-based milks not only gain antioxidant properties but may also support gut health indirectly by reducing inflammation in the digestive tract. In this role, apigenin bridges food science and nutrition, transforming everyday foods into vehicles for targeted health support.
Cosmetics: Natural Solutions for Skin Health and Beauty
Apigenin bulk powder has emerged as a sought-after ingredient in cosmetic formulations, thanks to its dual benefits for skin health and aesthetic enhancement. Its antioxidant activity combats free radical damage from UV radiation and pollution, preventing premature aging signs such as fine lines, wrinkles, and uneven skin tone—making it a staple in anti-aging serums, creams, and sunscreens. For sensitive or acne-prone skin, its anti-inflammatory properties soothe redness and irritation, reducing breakouts and supporting a clearer complexion.
Apigenin also contributes to skin brightening by inhibiting melanin production, helping to fade dark spots and promote a more even skin tone in whitening products. Its ability to strengthen the skin’s barrier function—by supporting collagen synthesis and reducing oxidative stress—makes it effective in moisturizers and repair creams, particularly for dry or damaged skin. As consumers increasingly prioritize natural and “clean” beauty ingredients, apigenin’s plant-derived origin and proven efficacy make it a valuable addition to formulations ranging from facial cleansers to anti-aging masks, blending science-backed results with botanical appeal.
OEM and ODM Services
KINTAI offers OEM and ODM services, providing businesses the opportunity to integrate the benefits of celery extract powder into their unique formulations.
OEM Services: Our company brands the product with its identity, ensuring consistency in the supply chain.
ODM Services: Flexibility in formulation and presentation to align the product with the business's brand identity and cater to specific consumer preferences.
These services enhance the adaptability of Banaba Leaf Extract Powder, meeting diverse requirements in various sectors.
Certifications
Advantage Of KINTAI
KINTAI is a professional manufacturer and supplier of Apigenin Bulk Powder. We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.
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