Sanguinarine Powder

Product

Xi'an Kintaihealth® stands as a leading producer of premium Macleaya Cordata Extract, specifically Sanguinarine Powder (CAS: 2447 - 54 - 3). Through advanced extraction and purification technologies, we deliver pharmaceutical - grade quality, with the key bioactive compound Sanguinarine maintained in its core form, ensuring high bioavailability for diverse applications.

  What is Sanguinarine Powder ？  

Sanguinarine Powder is a natural botanical extract derived from plants of the Macleaya cordata genus, with CAS number 2447 - 54 - 3. It is a bioactive alkaloid compound that has garnered significant attention in various industries.It boasts diverse applications. In agriculture, it serves as an effective natural pesticide component, helping control pests. In veterinary medicine, it can be used as a feed additive to support animal health. In cosmeceuticals, its properties contribute to skin care, such as anti - acne and antioxidant effects. Moreover, in pharmaceutical research, it shows potential in formulating anti - inflammatory, anti - tumor, and wound - healing products. Stringent quality controls cover aspects like particle size, heavy metals, and microbiological criteria, making it a reliable ingredient for multiple industrial uses.

  Kintai Sanguinarine Powder Advantages  

High Potency & Clinically - Backed Efficacy

Our Sanguinarine Powder, sourced from Macleaya cordata extract (CAS: 2447 - 54 - 3), delivers Pharmaceutical - Grade quality. With total alkaloids standardized (e.g., 60% total alkaloids, 40% sanguinarine as core actives), it’s rigorously analyzed via advanced methods (e.g., HPLC). The powder exhibits potent antibacterial, anti - inflammatory, and antioxidant properties. Every batch ensures consistent bioactivity, empowering development of high - performance products across industries.

Multi - Industry Application

• Agriculture & Veterinary：Acts as a natural pesticide/feed additive. Controls pests effectively while supporting animal gut health, reducing pathogenic bacteria, and enhancing overall wellness in livestock.

• Cosmeceuticals：Boosts skin resilience. Mitigates oxidative damage, regulates sebum, and soothes irritation, making it ideal for anti - acne, anti - aging skincare formulations.

• Pharmaceutical R & D：Shows promise in research for anti - inflammatory, anti - tumor, and wound - healing applications. Its alkaloid profile supports exploration of novel therapeutic solutions.

Strict Quality Control

Produced in a GMP - compliant facility, our Sanguinarine Powder ensures full traceability. Each batch comes with detailed Certificates of Analysis (COA), Material Safety Data Sheets (MSDS), and undergoes comprehensive testing for heavy metals (e.g., Pb, As), residual solvents (e.g., ethanol), and microbial contaminants. We prioritize safety and purity, delivering reliable ingredients for your innovation.

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  Sanguinarine Powder Extraction  

1. Raw Material Preparation

Select plant materials rich in sanguinarine, such as Macleaya cordata. Dry the materials thoroughly and crush them into fine particles.

2. Extraction

Employ solvent extraction methods, with ethanol or acidic aqueous solutions (e.g., hydrochloric acid solution) being commonly used. Mix the plant material with the solvent at a specific ratio, then heat the mixture for a certain duration to extract the sanguinarine.

3. Purification

Adsorb sanguinarine using ion - exchange resins or macroporous adsorption resins. Elute the resins with an appropriate solvent and collect the eluent containing sanguinarine.

4. Concentration and Drying

Concentrate the eluent under reduced pressure to remove the solvent. Dry the remaining substance to obtain the sanguinarine extract, typically in powder form.

5. Detection

Determine the content and purity of sanguinarine using analytical methods such as High - Performance Liquid Chromatography (HPLC).

  Sanguinarine Powder COA  

  Sanguinarine Powder Benefits  

2. Anti - Inflammatory Effects: By suppressing the activation of inflammatory pathways and reducing the production of pro - inflammatory cytokines, sanguinarine helps alleviate inflammation. It can be used in topical creams and gels to soothe skin irritations, rashes, and minor inflammatory conditions. In veterinary applications, it may assist in reducing inflammation in animals suffering from various diseases.

3. Antioxidant Activity: As a natural antioxidant, sanguinarine powder can neutralize free radicals in the body. Free radicals are unstable molecules that can cause oxidative stress, leading to cell damage and contributing to the development of chronic diseases like cancer, heart disease, and neurodegenerative disorders. Regular intake or topical use of products containing sanguinarine may help protect cells from oxidative damage and promote overall health.

4. Anticancer Potential: Research has shown that sanguinarine may have anticancer properties. It can induce apoptosis (programmed cell death) in cancer cells, inhibit tumor angiogenesis (the formation of new blood vessels that tumors need to grow and spread), and suppress the migration and invasion of cancer cells. While more studies are needed, these findings suggest its promise in cancer prevention and treatment research.

5. Wound Healing Support: Sanguinarine promotes wound healing by stimulating cell proliferation and collagen synthesis. It can help reduce the risk of wound infection due to its antimicrobial activity, and accelerate the closure and regeneration of damaged tissue. This makes it useful in wound - care products, both for human and veterinary applications.

6. Oral Health Improvement: In oral care products, sanguinarine powder can prevent plaque formation, reduce gingivitis, and freshen breath. It works by interfering with the adhesion of bacteria to tooth surfaces and reducing the metabolic activity of oral pathogens, thus contributing to better oral hygiene and overall oral health.

7. Skin Rejuvenation: When used in skincare formulations, sanguinarine can enhance skin texture and tone. Its antioxidant and anti - inflammatory properties help reduce the appearance of fine lines, wrinkles, and age spots. It also promotes skin cell turnover, resulting in a more youthful and radiant complexion.

8. Agricultural Applications: In agriculture, sanguinarine powder serves as a natural pesticide. It can repel and kill various pests that damage crops, offering an eco - friendly alternative to synthetic pesticides. Additionally, when added to animal feed, it can improve animal growth performance and enhance the immune system, contributing to healthier livestock production.

  Sanguinarine Powder Applications  

1. Oral Care Products：In the oral hygiene industry, sanguinarine powder is a key ingredient in toothpastes, mouthwashes, and dental gels. It effectively reduces plaque formation by inhibiting the adhesion of oral bacteria like Streptococcus mutans to tooth surfaces. Mouthwashes containing sanguinarine can combat bad breath by targeting odor - causing bacteria, while also helping to prevent gingivitis through its antibacterial and anti - inflammatory properties.

2. Skincare Formulations：Sanguinarine is incorporated into various skincare products such as creams, serums, and masks. In anti - aging formulations, it promotes collagen synthesis, improving skin elasticity and reducing the appearance of fine lines and wrinkles. For acne - prone skin, its antibacterial action helps eliminate acne - causing bacteria, while the anti - inflammatory effect soothes inflamed pimples and reduces redness.

3. Pharmaceutical Research and Development：In the pharmaceutical field, sanguinarine powder is used in research for developing drugs targeting different diseases. Its potential anti - cancer properties make it a subject of study for creating novel anti - tumor therapies. Scientists are also exploring its use in developing medications for neurodegenerative diseases, taking advantage of its antioxidant and anti - inflammatory abilities to protect neurons from damage.

4. Veterinary Medicine：Veterinarians use sanguinarine - based products to improve animal health. It can be added to animal feed as an additive to enhance the immune system of livestock, reducing the risk of infections. Sanguinarine - containing topical treatments are also applied to treat skin conditions and wounds in animals, thanks to its antibacterial and wound - healing properties.

5. Agricultural Pesticides：In agriculture, sanguinarine powder serves as a natural pesticide. Farmers use it to protect crops from pests, as it can repel and even kill insects that damage plants. This natural alternative to synthetic pesticides helps reduce the environmental impact of farming while still effectively safeguarding the harvest.

6. Food and Beverage Preservation：Although less common, sanguinarine's antibacterial properties make it a potential natural preservative in the food and beverage industry. It can be used to inhibit the growth of spoilage - causing bacteria, extending the shelf - life of certain products without the use of synthetic chemicals.

  Sanguinarine Powder Dosage Recommendation  

  Safety of Kintai's Sanguinarine Powder  

· Acute Toxicity: Sanguinarine is a natural alkaloid with moderate toxicity. Animal studies show LD₅₀ values (oral) typically range from 20-100 mg/kg in rodents, indicating potential harm if ingested in high doses. Kintai’s product specifications likely include toxicity testing to ensure compliance with safety standards.

· Chronic Exposure Risks: Prolonged exposure to high concentrations may cause cellular irritation or organ toxicity. Kintai’s quality control processes may include limits on residual toxins and impurities to minimize long-term risks.

2. Quality Control & Safety Certifications

 Purity & Purity Testing:

· Pharmaceutical-grade products (≥98% purity) and nutraceutical-grade (≥95%) undergo HPLC analysis to confirm purity, reducing risks from contaminants.

· COA (Certificate of Analysis) provided by Kintai includes tests for heavy metals (e.g., arsenic, lead), residual solvents, and microbial contaminants (e.g., E. coli, salmonella).

Manufacturing Standards:

· Produced in GMP-compliant facilities to ensure consistent quality and safety.

· MSDS (Material Safety Data Sheet) available, detailing handling precautions, emergency procedures, and toxicological data.

4. Handling & Storage Precautions

· Physical Hazards: Powder form may pose inhalation risks; use in well-ventilated areas.

· Storage: Store in a cool, dry place away from direct sunlight and moisture to maintain stability.

· Disposal: Follow local regulations for chemical waste disposal to prevent environmental contamination.

5. Regulatory Compliance

· Kintai’s sanguinarine powder may comply with international standards (e.g., FDA, EFSA, WHO) for food additives, pharmaceuticals, or agricultural chemicals, depending on the intended use.

· For pharmaceutical applications, the product may adhere to ICH guidelines for safety testing in drug development.

6. Safety Warnings & Limitations

· Contraindications: Not recommended for pregnant or lactating individuals without medical advice.

· Overexposure Symptoms: May include nausea, vomiting, or organ dysfunction if ingested in large quantities. Seek medical attention immediately in case of accidental exposure.

· Non-Clinical Use: For research or industrial purposes only unless explicitly approved for human consumption or medical use.

  Why Choose Sanguinarine Powder by Kintaihealth®?  
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce sanguinarine powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

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