China Manufacturers Best Suppliers supply High Quality Water Soluble Mangiferin for sale

Xi'an Kintaihealth® stands as a leading producer of premium Water Soluble Mangiferin (CAS: 4773-96-0). Through cutting-edge extraction and purification techniques, we provide pharmaceutical-grade products, maintaining mangiferin in its most bioactive water-soluble state. This ensures optimal absorption and effectiveness across various applications. Our strict quality control measures guarantee consistency in purity and potency, making our Water Soluble Mangiferin a reliable choice for industries seeking high-quality natural ingredients. Whether for use in functional beverages, dietary supplements, pharmaceuticals, or skincare, our product's superior water solubility and bioavailability supports the development of top-tier formulations.

     Kintai Water Soluble Mangiferin Advantages     

High Potency & Clinical Efficacy

Kintai's Water Soluble Mangiferin (CAS: 4773-96-0) offers pharmaceutical-grade purity (≥98% by HPLC), enhanced by water-soluble modification for better absorption. Clinically proven for:

· Strong antioxidant effects (DPPH IC₅₀ ≤10 μM) to fight free radicals.

· Improved glucose/lipid metabolism, supporting diabetes research.

· Neuroprotection by crossing the blood-brain barrier.

· 300% higher bioavailability than standard mangiferin.

Multi-Industry Applications

· Food & Drinks: Antioxidant in sports drinks (0.1–0.5g/L) or sugar-free supplements (50–100mg/serving).

· Pharmaceuticals: Oral use for metabolic health (200–400mg/day) and topical creams for skin issues.

· Cosmetics: Anti-aging serums (0.5–2%) and sensitive skin care.

· Agriculture: Feed additives (10–20mg/kg) for livestock immunity.

Strict Quality Control

· Purity Tests: HPLC-verified ≥98% purity, with heavy metals (Pb≤2ppm, As≤1ppm) and solvent limits.

· Stability: Water-soluble (≥100g/L) and shelf-stable for 24 months (40℃/75% RH).

· Compliance: GMP-certified, with COA/MSDS and FDA/EFSA/WHO standards met.

     Water Soluble Mangiferin Production Process     

I. Raw Material Pretreatment

Select mango leaves, fruits, or kernels rich in mangiferin. Dry and grind them into 30 - 60 mesh powder. If using kernels, remove the shell first.

II. Water - Soluble Extraction Methods

Weak Alkaline Solution Extraction：Use pH 8 - 9 solutions (lime water or Na₂CO₃) with vitamin C for antioxidant protection. Extract at 50 - 60°C with a 1:10 - 1:12 material - to - solvent ratio for 2 hours, repeat twice. Alkaline conditions boost extraction rate (>80%).

Hot Water Extraction：Extract with 80 - 90°C hot water, followed by resin purification to remove impurities.

Enzyme - Assisted Extraction：Pre - treat with cellulase or pectinase (pH 5.0, 50°C) to break cell walls. Then extract with water or weak alkaline solution, reducing organic solvent use.

III. Separation and Purification

Filter the extract and concentrate it under reduced pressure (1/5 - 1/10 of original volume). Use AB - 8, D101 or HPD100 resins for purification:

· Wash with water to remove sugars

· 30% ethanol for alcohol - soluble impurities

· 60 - 70% ethanol to elute mangiferin

Concentrate the eluate, crystallize at low temperature, and recrystallize twice with 60% methanol/ethanol for 99% purity.

IV. Optimization Tips

· Weak alkaline water extraction is ideal for industrial use; combine with enzymes for higher purity.

· Keep temperature below 60°C to prevent degradation.

· Ultrasonic assistance (40 - 50°C) speeds up extraction.

     kintai Mangiferin Solubility in Water     

Product Technical Specifications​

· Active Ingredient: Determined by Ultra-High Performance Liquid Chromatography with Photodiode Array Detection (UHPLC-PDA), the mangiferin content reaches ≥15%.​

· Appearance: Appears as a pale brown powder with a distinctive odor.​

· Batch Consistency: Accelerated stability tests demonstrate excellent batch-to-batch consistency, with a Relative Standard Deviation (RSD) <2%.​

· Extraction Process: Utilizes an ethanol-water extraction technique, ensuring the finished product is free of solvent residues.​

Exceptional Water Solubility​

kintaihealth® mangiferin exhibits industry-leading dissolution performance. Its solubility in water exceeds 150 mg/mL, representing a 1350-fold improvement compared to natural mangiferin. Verified under room temperature (RT) and 65℃ conditions, 1 gram of this product can completely dissolve in 100mL of water, and leaves no residue after dissolution in beverage systems.​

Rigorous Testing Protocols​

· Testing Method: Precise detection is carried out using the HACH 2100AN Turbidimeter.​

· Testing Conditions: Tests are conducted within a pH range of 3.0 - 8.0 and a temperature gradient of 0 - 45℃.​

· Acceptance Criteria: During the temperature increase from 25℃ to 45℃, the turbidity change ΔNTU <2.0, ensuring stable and reliable product quality.​

Patent Certification​

The production technology of kintaibio® mangiferin powder has obtained national patent certification, with the patent number CN113416182B, demonstrating its technological innovation capabilities and product quality assurance.

     Water Soluble Mangiferin Benefits     

Water Soluble Mangiferin offers numerous benefits across health, wellness, and various industries:

1. Powerful Antioxidant Defense: As a potent antioxidant, Water Soluble Mangiferin effectively neutralizes free radicals, reducing oxidative stress in the body. It helps protect cells from damage caused by factors like pollution, UV radiation, and aging, thereby contributing to overall health and potentially lowering the risk of chronic diseases such as heart disease and certain cancers.

2. Enhanced Metabolic Health: This compound has shown promise in regulating metabolism. It can improve glucose tolerance and lipid profiles, making it beneficial for managing blood sugar levels and reducing the risk of metabolic syndrome. It may also aid in weight management by influencing fat metabolism and energy expenditure.

3. Neuroprotective Properties: Water Soluble Mangiferin can cross the blood-brain barrier, offering protection to the nervous system. It helps inhibit the aggregation of amyloid - β proteins, which are associated with neurodegenerative diseases like Alzheimer's. By reducing inflammation and oxidative damage in the brain, it may support cognitive function and slow down age-related cognitive decline.

4. Anti - Inflammatory Effects: With its strong anti-inflammatory capabilities, it can alleviate inflammation in the body. This is useful for managing conditions characterized by chronic inflammation, such as arthritis, inflammatory bowel disease, and skin disorders. It works by suppressing the production of pro - inflammatory cytokines and enzymes.

5. Improved Skin Health: In the realm of skincare, Water Soluble Mangiferin's antioxidant and anti-inflammatory properties make it a valuable ingredient. It helps combat signs of aging by reducing wrinkles, fine lines, and hyperpigmentation. It also soothes irritated skin, promotes collagen production, and improves skin texture and elasticity.

6. Industrial Applications: Beyond health, it serves as a natural additive in various industries. In the food and beverage sector, it acts as an antioxidant and preservative, extending the helf life of products while enhancing their nutritional value. In agriculture, it can be used in animal feed to boost immunity and improve growth performance in livestock. 

     Water Soluble Mangiferin Applications     

Functional Food and Beverages
Water Soluble Mangiferin serves as a natural additive in functional foods and beverages. In sports drinks, it can be included at a concentration of 0.1–0.5g/L to enhance antioxidant properties, providing consumers with protection against oxidative stress during intense physical activity. For dietary supplements, it’s formulated into capsules or powders, with each serving typically containing 50–100mg, to support overall health and wellness. In yogurt or fruit - based products, it not only adds nutritional value but also acts as a natural preservative, extending shelf life by preventing oxidative degradation.

Pharmaceutical Formulations
In the pharmaceutical industry, Water Soluble Mangiferin is used in both oral and topical formulations. For oral medications targeting metabolic syndrome, daily dosages of 200–400mg are common, helping regulate blood sugar and lipid levels. In topical creams and ointments, it’s applied at concentrations of 0.5–2% to treat skin conditions such as eczema and psoriasis, leveraging its anti - inflammatory and antioxidant properties to soothe irritated skin and promote healing. It also shows promise as an adjuvant in anti - cancer drugs, potentially enhancing the efficacy of treatment while reducing side effects.

Cosmetics and Personal Care Products
Cosmetic brands incorporate Water Soluble Mangiferin into a wide range of products. In anti - aging serums, it helps reduce the appearance of wrinkles and fine lines by stimulating collagen production and protecting skin cells from free radical damage. In facial masks and moisturizers designed for sensitive skin, it calms inflammation and redness, improving skin texture and comfort. Additionally, it’s used in hair care products, such as shampoos and conditioners, to strengthen hair follicles and promote a healthy scalp by reducing oxidative stress.

Animal Feed and Agriculture
In agriculture, Water Soluble Mangiferin is added to animal feed at a rate of 10–20mg/kg to enhance the immune system of livestock. This improves their overall health, reduces the incidence of diseases, and boosts growth performance. For poultry, it can lead to better egg quality and increased resistance to infections. In aquaculture, it’s used in fish feed to improve fish health, growth rate, and flesh quality. Moreover, it can be formulated into plant - based pesticides or fertilizers, providing natural protection against pests and promoting plant growth through its antioxidant and antibacterial properties.

Research and Development

Water Soluble Mangiferin is a valuable compound in scientific research. Researchers use it to study its mechanisms of action in various biological processes, such as neurodegeneration, inflammation, and metabolism. It serves as a key ingredient in in - vitro and in - vivo experiments, helping scientists explore its potential applications in drug discovery, functional food development, and personalized medicine. Its water - soluble nature makes it easier to incorporate into experimental models, facilitating more accurate and reliable results

.

     Water Soluble Mangiferin Dosage Recommendation     

     Safety of KINTAI’S Water Soluble Mangiferin     

Toxicological Considerations

Water soluble mangiferin from KINTAI exhibits low acute toxicity, with no reported adverse effects at recommended doses. Animal studies show an oral LD₅₀ exceeding 2000 mg/kg, indicating minimal risk of severe harm. Chronic exposure is generally safe, but high concentrations may cause mild gastrointestinal discomfort in sensitive individuals. KINTAI conducts routine toxicity testing to ensure safety compliance.

Quality Control & Safety Certifications

Manufactured in GMP-compliant facilities, KINTAI’s product maintains ≥98% purity verified by HPLC. Each batch undergoes rigorous testing for heavy metals (Pb ≤2ppm, As ≤1ppm), residual solvents, and microbial safety. A Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) are provided, ensuring compliance with international standards (FDA, EFSA, WHO).

Safety Warnings & Limitations

· Contraindications: Not recommended for pregnant/lactating women without medical advice due to limited safety data.

· Adverse Reactions: May cause mild stomach upset if taken in excessive doses. Discontinue use if discomfort occurs.

· Handling: Avoid inhalation of powder; use in well-ventilated areas. Store in a cool, dry place away from direct sunlight.

     Why Choose Water Soluble Mangiferin Powder by Kintaihealth®?     

1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Water Soluble Mangiferin powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

About Us

OEM and ODM Services

At KINTAI, we understand the significance of customization. Our Original Equipment Manufacturing( OEM) and Original Design Manufacturing( ODM) services empower you to conform it to meet your specific conditions. This inflexibility, coupled with our intertwined service results, ensures that your unique vision is brought to life seamlessly.

Certifications

  KINTAI  Advantage       

KINTAI is a professional manufacturer and supplier of Water Soluble Mangiferin, We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.

  Parcel and Shipping   

1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed

Contact Us

In conclusion, KINTAI's Water Soluble Mangiferin stands as a testament to our unvarying commitment to quality, invention, and client satisfaction. We invite professional buyers and global dealers to witness the epitome of chastity and efficacity. For inquiries or to order your batch of the product, contact us at info@kintaibio.com. Our fast delivery and secure packaging ensure that you receive excellence in every package. Choose KINTAI for it – where quality meets innovation.

Hot Tags: phloretin powder, phloretin bulk powder, manufacturers, suppliers, factory, buy, price, for sale