Natural Ferulic Acid
CAS No: 1135-24-6
Specification: 98% ferulic acid
Appearance: White powder
Test Method: HPLC
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Payment: Multiple terms acceptable like T/T, LC, DA
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
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Product Introduction
Product Details
What is Natural Ferulic Acid?
Natural ferulic acid is a kind of plant phenolic acid extracted from rice bran. It has many health functions, such as anti-oxidation, scavenging free radicals, antibacterial and anti-inflammatory, anti-tumor, etc., and its toxicity is very low, and it is easy to be metabolized by the human body. It has a wide range of applications in medicine, health care products,-cosmetic raw materials and other fields.
Natural Ferulic Acid Chemical & Physical Properties
CAS Number | 1135-24-6 | Density | 1.316 g/cm3 |
Molecular Formula | C10H10O4 |
Molecular Weight | 194.18 |
Melting Point | 168-172 ℃ (lit.) |
Boiling Point | 250.62 ℃ (rough estimate) |
Solubleness | Soluble in DMSO (a little), methanol (a little) | Test Method | HPLC |
Natural Ferulic Acid Functions
1. Antioxidant Activity: Beyond Free Radical Scavenging
Natural ferulic acid is recognized as a potent antioxidant with multifaceted protective effects:
- Free radical neutralization: It efficiently scavenges reactive oxygen species (ROS) such as superoxide anions and hydroxyl radicals, which are generated by UV radiation, pollution, and cellular metabolism. By reducing oxidative stress, it prevents lipid peroxidation in cell membranes and DNA damage, thereby slowing down cellular aging.
- Synergistic antioxidant effects: When combined with other antioxidants like vitamin C or vitamin E, ferulic acid enhances their stability and efficacy. For example, in skincare formulations, this synergy boosts protection against UV-induced photodamage, reducing redness, dryness, and long-term skin aging (e.g., wrinkles and age spots).
- Collagen preservation: It inhibits the activity of collagenase, an enzyme that breaks down collagen. By preserving collagen fibers, ferulic acid helps maintain skin elasticity and firmness, making it a valuable ingredient in anti-aging products.
2. Bacteriostatic and Anti-Inflammatory Properties: Broad-Spectrum Protection
Ferulic acid’s antimicrobial and anti-inflammatory actions extend to both microbial defense and immune regulation:
- Bacteriostatic spectrum: It exhibits inhibitory effects on a range of pathogens, including Gram-negative bacteria (Escherichia coli), Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus), and fungi (yeast). This makes it useful in natural preservatives for cosmetics, pharmaceuticals, and even food products, reducing reliance on synthetic antimicrobials.
- UV-induced inflammation mitigation: UV radiation triggers the release of pro-inflammatory cytokines (e.g., interleukin-1β and tumor necrosis factor-α) in the skin, leading to redness, swelling, and sunburn. Ferulic acid suppresses this cytokine release, alleviating acute inflammatory responses and reducing the risk of long-term UV-related skin damage (e.g., photocarcinogenesis).
- Skin barrier support: By reducing inflammation, it helps strengthen the skin’s protective barrier, making it more resilient to external irritants and reducing susceptibility to conditions like eczema or dermatitis.
3. Improving Local Blood Circulation: Targeted Relief for Swelling and Inflammation
Ferulic acid’s ability to enhance blood flow contributes to its therapeutic potential in managing inflammation and trauma:
- Promoting circulation: It dilates local blood vessels, increasing blood flow to inflamed or injured tissues. Improved circulation accelerates the removal of metabolic waste and delivers oxygen and nutrients, facilitating tissue repair.
- Swelling reduction: In cases of soft tissue injuries (e.g., sprains, bruises, or falls), it helps dissipate accumulated fluid and inflammatory mediators, relieving edema and discomfort. This makes it a common ingredient in topical analgesics or traditional medicine formulations for traumatic swelling.
- Pain alleviation: By reducing inflammation and improving circulation, it indirectly eases pain associated with injuries, as swollen tissues put less pressure on nerve endings.
4. Anti-Tumor Effects: Mechanisms and Therapeutic Potential
Ferulic acid’s anti-cancer properties are supported by research targeting multiple stages of tumor development:
- Inhibiting tumor cell proliferation: It disrupts the cell cycle of cancer cells (e.g., in liver and lung cancer) by suppressing the activity of enzymes involved in DNA replication, slowing down uncontrolled growth.
- Inducing apoptosis: In various tumor types, including uterine fibroids and breast cancer, ferulic acid triggers programmed cell death (apoptosis) by activating pro-apoptotic proteins, selectively eliminating abnormal cells.
- Anti-angiogenesis: Tumors rely on new blood vessel formation to obtain nutrients. Ferulic acid inhibits the production of vascular endothelial growth factor (VEGF), a key driver of angiogenesis, thereby starving tumors of their blood supply.
- Enhancing chemo-sensitivity: It may improve the efficacy of conventional chemotherapy drugs by sensitizing resistant tumor cells, reducing the required dosage and minimizing side effects.
Natural Ferulic Acid Applications
1. Beauty and Cosmetics: A Multi-Functional Ingredient
Ferulic acid’s diverse properties make it a staple in cosmetic formulations, extending beyond basic skincare:
- Anti-aging formulations: Its antioxidant prowess combats free radicals from UV rays and pollution, reducing collagen breakdown and minimizing fine lines. It is often paired with vitamins C and E in serums and creams to boost stability, enhancing long-term anti-aging effects.
- Sunscreen enhancement: As a natural UV absorber, it complements chemical or physical sunscreens by absorbing UVB rays, reducing sunburn risk, and preventing photoaging (e.g., dark spots and rough texture).
- Whitening and brightening: By inhibiting tyrosinase, the enzyme responsible for melanin production, ferulic acid fades hyperpigmentation, acne scars, and age spots, promoting a more even skin tone. It is commonly found in whitening masks, lotions, and spot treatments.
- Soothing sensitive skin: Its anti-inflammatory properties calm redness and irritation, making it suitable for products targeting rosacea, post-sun exposure, or acne-prone skin. It also strengthens the skin barrier, reducing moisture loss.
2. Medicine and Health: Therapeutic Versatility
Ferulic acid’s bioactive profile supports its use in pharmaceuticals and health interventions:
- Cardiovascular and cerebrovascular care: Formulated into tablets, capsules, or injections, it helps improve blood circulation by dilating blood vessels and reducing platelet aggregation, aiding in the treatment of conditions like hypertension, atherosclerosis, and ischemic stroke. It also lowers oxidative stress in blood vessels, protecting against endothelial damage.
- Anti-tumor adjunct therapy: In oncology, it is used alongside conventional treatments (chemotherapy, radiotherapy) to enhance efficacy. For example, it may sensitize liver or lung cancer cells to drugs, reduce tumor growth, and alleviate treatment-related side effects like inflammation.
- Anti-inflammatory and analgesic applications: Topical ointments or oral preparations containing ferulic acid relieve pain and swelling from injuries (e.g., sprains, bruises) by promoting blood flow and reducing pro-inflammatory cytokines. It is also explored for managing chronic inflammatory conditions like rheumatoid arthritis.
- Neurological support: Emerging research suggests it may protect neurons from oxidative damage, potentially aiding in preventing or managing neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
3. Food Industry: Safety and Functionality
Ferulic acid’s natural origin and properties make it a valuable additive in food production:
- Natural antioxidants: Added to processed foods (e.g., oils, snacks, and baked goods), it inhibits lipid oxidation, extending shelf life by preventing rancidity. Unlike synthetic antioxidants (e.g., BHA, BHT), it appeals to consumers seeking clean-label products.
- Food preservatives: Its bacteriostatic effects against pathogens like E. coli and Staphylococcus aureus help prevent spoilage in refrigerated or packaged foods (e.g., dairy products, sauces, and fruit juices), reducing reliance on chemical preservatives.
- Functional food fortification: Included in health-oriented products (e.g., energy bars, fortified cereals, and functional beverages), it boosts antioxidant content, supporting consumer demand for foods with added nutritional benefits. It may also enhance the stability of other bioactive ingredients in these products.
- Flavor and color protection: In plant-based foods, it helps preserve natural pigments (e.g., carotenoids) and flavors, maintaining product quality during storage and processing.
4. Emerging Applications
- Agriculture: Used as a natural pesticide or plant growth regulator, ferulic acid can inhibit the growth of harmful fungi and pests, supporting organic farming practices.
- Biomedical materials: Incorporated into wound dressings or biodegradable implants, it promotes tissue repair through its anti-inflammatory and antioxidant properties, reducing infection risk and accelerating healing.
Ferulic acid’s adaptability—from enhancing skincare efficacy to supporting food safety and medical treatments—solidifies its role as a versatile ingredient across industries, with ongoing research unlocking new potential uses.
OEM and ODM Services
KINTAI offers comprehensive OEM and ODM services to meet your specific requirements. We have a committed innovative work place, best-in-class fabricating offices, and a group of experienced experts. Our administrations incorporate item customization, definition advancement, bundling plans, and private naming. We value collaboration and strive to provide integrated solutions that meet your needs and exceed your expectations.
FAQ
Here are some frequently asked questions about natural ferulic acid:
1. Is it safe to use?
Yes, rice bran extract powder is safe for topical and oral use. In any case, it is constantly prescribed to play out a fix test and talk with medical care proficient before use.
2. Might it at any point be utilized with other skincare fixings?
Absolutely! ferulic acid bulk works synergistically with different cancer prevention agents, like nutrients C and E. It tends to be integrated into different skincare definitions to upgrade their adequacy.
3. Might it at any point be utilized during pregnancy?
In spite of the fact that ferulic acid bulk is for the most part thought to be protected, it is prudent to talk with a medical services professional prior to utilizing any new item during pregnancy or breastfeeding.
In conclusion, KINTAI is a professional manufacturer and supplier of rice bran extract powder. We have a well-equipped research and development center, state-of-the-art production facilities, and a commitment to quality. Our customizable products, integrated service solutions, fast delivery, and secure packaging make us the ideal choice for your natural ferulic acid needs. For inquiries, please contact us at info@kintaibio.com.
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