Harmine powder

Plant Source: Peganum harmala
Extract Source:100% Natural
Origin:China
CAS Number:442-51-3
Other Name:Peganum Harmala Extract
Specification: 98%Harmine
Test Method: HPLC
Appearance: Beige powder
Certifications: ISO, HACCP, HALAL, KOSHER, Technical Invention Patent Certificate
Biogenic origin: hermala, harmel
Applications: Food, Health Care Products, Medicine, Cosmetics
Lead time: 1-3 days
Shelf Life: Two years
Storage: Store in a well-closed container away from moisture and direct sunlight.Keep in cool dry place
Payment: Multiple terms acceptable like T/T, L/C, DA
Sample: Free sample available
KINTAI's Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, Non-Irradiated/treat by heat only.
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

Harmine Supplier

Peganum harmala is a perennial herbaceous plant widely distributed in arid and semi-arid regions such as Central Asia, the Middle East, North Africa, and Southern Europe. In China, it is also common in the northwest region. Harmine is a type of alkaloid extracted from Peganum harmala.​​​​​​​

Healthkintai® is a professional plant extract production company that provides customers with high-purity and standardized powder products of Harmine powder.

We always focus on excellent quality and innovative technology. We have strict quality control and use advanced testing technology to ensure stable levels of active ingredients in each batch of products. We can provide you with flexible customization services, including OEM&ODM services. Our products are of good quality and affordable. With the ability to integrate the entire industry chain, we provide customers with cost-effective solutions.

We are committed to providing customers with safe, effective, and stable Harmine. Welcome to contact us.

Kintai Harmine Spcification

Product

Spcification

Appearance

Harmine

98%Harmine

Beige powder

Dehydroharponine

98%Dehydroharponine

White powder

Harponine hydrochloride

98%Harponine hydrochloride

Yellow powder

Dehydroharponine hydrochloride

Dehydroharponine hydrochloride

White powder

Physical and Chemical Properties of Harmaline

Property Type

Description

Molecular Formula

C₁₃H₁₄N₂O

Solubility

Water:Very slightly soluble / Sparingly soluble

Organic Solvents:Soluble in ethanol, methanol, chloroform, DMSO; slightly soluble in ether and benzene

Acids:Forms water-soluble salts (e.g., hydrochloride salt)

Stability

Stable under recommended storage conditions (cool, dry, away from light). Sensitive to prolonged exposure to air and light, which may cause oxidation and darkening.

Harmine  Safty

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Harmaline has significant psychoactive and physiological toxicity, and its use without professional guidance is extremely dangerous.

Its toxicity mainly stems from the strong monoamine oxidase inhibitor (MAOI) effect. Neurotoxicity: produces strong hallucinations, confusion, anxiety, tremors, and convulsions. Physiological reactions: leading to nausea, vomiting, elevated body temperature, tachycardia, and severe motor dysfunction.

Therefore, Harmaline is not a substance that can be safely used in daily life, and is limited to strict scientific research or controlled by experienced guides in a very small number of traditional rituals.

Harmine Functions

1. Neuropharmacological function: monoamine oxidase inhibitor (MAOI)

The most essential function of camel antler alkaloid is its powerful reversible monoamine oxidase A inhibitor (RIMA) activity. It can significantly inhibit monoamine oxidase, especially type A enzyme (MAO-A), in the brain and peripheral nervous system, thereby preventing the breakdown of monoamine neurotransmitters such as serotonin (5-HT), dopamine (DA), and norepinephrine (NE). It is based on this mechanism that it is used in traditional hallucinogens.

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2. Potential anti parasitic and antibacterial functions

In traditional medicine, the plant Peganum harmala, which is the source of Peganum harmala, is often used to treat parasitic infections. Modern research has confirmed that Peganum harmala does indeed have significant antiparasitic activity, especially against protozoan parasites such as Leishmania and Trypanosoma, as well as certain tapeworms.

3. Research prospects of anti-tumor and neuroprotection

In modern pharmacological research, Harmine powder have shown promising anti-tumor potential. Research has shown that it can combat various cancer cell lines in vitro and animal models through various pathways such as inhibiting cell proliferation, inducing tumor cell apoptosis, and inhibiting angiogenesis. But all of this is still in the preclinical research stage.

Harmine Benefits

1.For depression

Scientists' research shows that  harmine has antidepressant effects, possibly due to its interaction with the MAO-A enzyme and the serotonin 5-HT2A receptor. The psychotherapeutic use of indole alkaloids derived from magic mushrooms shows potential as an alternative to the synthetic antidepressant drugs currently on the market. 

2.For brain health

Preclinical studies suggest that harmine may have neuroprotective and cognitive-enhancing effects. Observational investigations of the mental health of long-term ayahuasca users indicate that prolonged use of this harmine-rich hallucinogen is associated with better neuropsychological functioning. Harmine shows promise as a safe and effective therapeutic agent for treating neuropsychiatric disorders.

3.For cognitive function and memory

Research involving hippocampal cell cultures and animal models show Harmine powder associated with neuroprotective effects, such as reducing excitotoxicity, inflammation, and oxidative stress and increasing brain-derived neurotrophic factor levels, helping to improve memory and learning

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