Ligustrazine powder

Ligustrazine powder Supplier

Ligusticum chuanxiong is a very famous and commonly used traditional Chinese medicine with a long history of medicinal use in China. It is actually the dried rhizome of the plant Chuanxiong. Chuanxiong is mainly produced in Sichuan and cultivated in Yunnan, Guizhou, Guangxi and other places. Chuanxiong is not cold resistant and generally grows in a mild and humid environment. It is suitable for planting in loose, fertile, well drained, and humus rich neutral or slightly acidic sandy loam soil.Kintai's Ligustrazine is extracted from high-quality Chuanqiong from China.

Healthkintai® is a professional plant extract company. We have a professional R&D team and a large production factory, which can provide you with customized services and offer you high-quality and high standard Ligustrazine.If you have any questions about Kintai Ligustrazine , please feel free to contact us.

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Ligustrazine for Intestinal

Due to the fact that the main component of ligustrazine hydrochloride is ligustrazine, it can reduce oxygen free radicals and exert antioxidant effects, effectively inhibiting the systemic inflammatory response of AP patients. This suggests that the combination therapy of ligustrazine with ustervastatin and octreotide has a better intestinal mucosal barrier protection effect. Ligustrazine can also improve intestinal microcirculation by correcting the balance of thromboxane A2/prostacyclin, thereby exerting a protective effect on the intestinal barrier. Therefore, the combination therapy of ligustrazine with ustertine and octreotide can help promote intestinal function recovery and reduce intestinal damage.

（reference： Efficacy of Ligustrazine Hydrochloride Combined with Ulinastatin and Octreotide in theTreatment of Acute Pancreatitis and Its Influence on the Level of Inflammatory Factors，LIAO Yuanhang, ZHONG Guping, XIE PingYichun People's Hospital, Yichun Jiangxi 336000, China.）

Ligustrazine Benefits

Efficient improvement of microcirculation and antiplatelet aggregation: The core advantage of ligustrazine hydrochloride is its strong ability to promote blood circulation and remove blood stasis. It can effectively inhibit platelet overactivation and aggregation, reduce blood hypercoagulability, and prevent the formation of small blood clots. At the same time, it can dilate small arteries and capillaries, significantly improve microcirculation disorders, increase blood flow and oxygen supply to tissues and organs, laying the foundation for the treatment of ischemic diseases.

Significant cardiovascular and cerebrovascular protective effects: With its improved blood flow and anti thrombotic properties, ligustrazine hydrochloride has outstanding protective effects on the cardiovascular and cerebrovascular system. It can dilate coronary arteries, increase myocardial blood supply, and alleviate angina pectoris; At the same time, it can dilate cerebral blood vessels, increase cerebral blood flow, and protect ischemic brain tissue. Therefore, it is widely used in clinical practice as an adjuvant therapy for ischemic cerebrovascular diseases, coronary heart disease, angina pectoris, etc., with definite therapeutic effects.

Clear antioxidant and neuroprotective potential: Studies have shown that ligustrazine hydrochloride has good antioxidant activity, can effectively eliminate free radicals, and alleviate oxidative stress damage to cells during ischemia-reperfusion. It can reduce the levels of inflammatory factors, inhibit neuronal apoptosis, and promote the recovery and regeneration of neural function, demonstrating significant neuroprotective effects, which are crucial for the recovery of post-stroke sequelae.

Good bioavailability and safety: As a chemical monomer drug, ligustrazine hydrochloride has clear ingredients and controllable quality. Its hydrochloride form has good water solubility and has relatively good absorption and bioavailability in vivo, whether taken orally or injected. Under the guidance of a doctor, standardized use results in relatively mild adverse reactions and overall high safety, making it a commonly used vascular protectant in clinical practice.

Ligustrazine Application

1. In the field of cardiovascular and cerebrovascular diseases

Ligustrazine is widely used in this field. It can effectively inhibit platelet aggregation, reduce blood viscosity, and prevent thrombosis; Simultaneously, it has the function of dilating coronary arteries, cerebral blood vessels, and peripheral blood vessels, significantly improving microcirculation and increasing blood flow. Widely used in clinical practice to treat ischemic cardiovascular and cerebrovascular diseases, such as cerebral infarction, cerebral ischemia, coronary heart disease, angina pectoris, etc., it is one of the commonly used drugs to improve patient prognosis and prevent recurrence.

2. Respiratory diseases field

Ligustrazine can be used as an adjuvant therapy for chronic lung diseases. It exerts its effects through multiple mechanisms such as anti-inflammatory, antioxidant stress, inhibition of pulmonary vascular smooth muscle cell proliferation, and alleviation of pulmonary arterial hypertension. In clinical practice, it is often used as an adjuvant drug to treat chronic obstructive pulmonary disease (COPD), pulmonary heart disease, and pulmonary arterial hypertension, which can effectively improve patients' lung function, hypoxia status, and quality of life.

3. diabetes complications

Ligustrazine shows a good prospect in the prevention and treatment of chronic complications of diabetes. It can improve the abnormal hemorheology of diabetes patients, protect the function of vascular endothelial cells, and alleviate tissue damage by inhibiting oxidative stress and inflammatory reaction. Therefore, it is often used to treat microvascular complications such as diabetes peripheral neuropathy, diabetes nephropathy and diabetes retinopathy, which helps to delay the disease process and protect organ functions.

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