Berberine Hydrochloride

Product Details

Kintaihealth® its Berberine Hydrochloride Powder stands out as a flagship product that perfectly integrates the brand’s commitment to natural wellness and scientific efficacy, with advantages deeply rooted in both the compound’s inherent properties and the company’s dedication to quality.​

Firstly, alignment with healthkintai’s "natural origin" philosophy is a core strength. Sourced from high-quality Coptis chinensis and related species, the berberine hydrochloride in this powder retains the purity of its botanical source—an approach that mirrors healthkintai’s focus on harnessing nature’s healing power. Unlike synthetic alternatives, this natural extraction process ensures the compound’s bioactivity is preserved, while avoiding unnecessary additives, making it a trusted choice for consumers seeking clean, plant-derived health solutions.

What is Berberine Hydrochloride Powder? 

Berberine Hydrochloride Powder is a kind of alkaloid extracted from Coptis chinensis and Coptis chinensis. It has extensive medicinal value. It is often used in the treatment of dysentery, acute gastroenteritis, chronic cholecystitis, conjunctivitis, suppurative otitis media and other diseases. It is often used in the treatment of dysentery and intestinal infection, and also has the effect of clearing heat and detoxification and antibacterial.

Berberine Hydrochloride Powder is a naturally occurring alkaloid extracted from the rhizomes of Coptis chinensis (Chinese goldthread) and other related Coptis species, which have been revered in traditional Chinese medicine for centuries for their potent therapeutic properties. This bioactive compound stands out for its extensive medicinal value, stemming from a unique combination of pharmacological actions that make it a versatile agent in modern clinical practice.​

In the realm of gastrointestinal disorders, it has long been a cornerstone in the treatment of dysentery, where it exerts a direct inhibitory effect on the causative pathogens such as Shigella spp., effectively curbing their proliferation and toxin production to alleviate severe diarrhea, abdominal cramps, and bloody stools. For acute gastroenteritis, it not only targets the infectious agents but also helps to soothe intestinal inflammation, reducing mucosal irritation and restoring normal peristalsis, thereby shortening the duration of symptoms like vomiting and watery diarrhea.​

Beyond the digestive system, its therapeutic reach extends to various other conditions. In chronic cholecystitis, it aids in reducing gallbladder inflammation by modulating the immune response and inhibiting the growth of bacteria that may contribute to recurrent infections, while also promoting bile flow to prevent stasis. For conjunctivitis, its topical application delivers antibacterial effects against common ocular pathogens like Staphylococcus aureus and Streptococcus pneumoniae, easing redness, swelling, and discharge. In suppurative otitis media, it penetrates the infected ear canal tissues to combat the underlying bacterial infection, curbing pus formation and relieving pain and hearing impairment associated with the condition.

ts prominent role in treating dysentery and other intestinal infections is rooted in its broad-spectrum antibacterial activity, which targets a range of gram-positive and gram-negative bacteria, including Escherichia coli and Salmonella, by disrupting their cell membranes and interfering with DNA replication. Moreover, aligning with its traditional use, it embodies the properties of clearing heat and detoxifying the body—a concept in traditional Chinese medicine that translates to its ability to reduce systemic inflammation, neutralize harmful substances, and restore the body's internal balance. This dual action of heat-clearing and antibacterial makes it not only effective in combating acute infections but also valuable in managing conditions where inflammation and microbial overgrowth coexist, highlighting its enduring relevance in both traditional and modern healthcare.

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COA of Berberine Hydrochloride Powder

Benefits of Berberine Hydrochloride Powder

Antibacterial Action: A Multifaceted Defense Against Pathogens​

Berberine hydrochloride powder exhibits a robust and broad-spectrum antibacterial activity that extends beyond basic inhibition, making it a cornerstone in combating infectious diseases. Its potency is particularly pronounced against intestinal pathogens: dysentery bacilli (e.g., Shigella spp.) and Escherichia coli are prime targets, as the compound disrupts their cell wall integrity, interferes with DNA replication, and inhibits the synthesis of essential proteins, effectively halting their proliferation. This dual mechanism not only kills existing bacteria but also prevents the spread of infection within the gastrointestinal tract.​

Beyond these key pathogens, it also acts against other harmful gut bacteria such as Salmonella, Staphylococcus aureus, and Pseudomonas aeruginosa, making it invaluable for treating complex intestinal infections. In clinical settings, this antibacterial action translates to rapid relief from symptoms like bloody diarrhea, abdominal tenesmus, and fever in dysentery cases. For non-specific intestinal infections, it reduces inflammation by curbing bacterial toxin production, thereby alleviating mucosal irritation and restoring normal digestive function. Its ability to target pathogens without significantly disrupting beneficial gut flora further enhances its therapeutic value, as it avoids the imbalances often caused by broad-spectrum antibiotics.​

Anti-arrhythmic Effects: Modulating Cardiac Function at a Cellular Level​

The anti-arrhythmic properties of berberine hydrochloride powder stem from its direct interaction with cardiac tissues, where it exerts precise regulatory effects on myocardial electrophysiology. Studies indicate it acts on ion channels in cardiac cells, particularly by inhibiting excessive sodium and calcium influx while regulating potassium efflux—key processes that stabilize the heart’s electrical activity. This modulation helps normalize abnormal heart rhythms, such as atrial fibrillation, ventricular premature beats, and supraventricular tachycardia, by prolonging the refractory period of cardiac muscle and preventing erratic impulse conduction.​

In patients with heart failure, its benefits extend beyond rhythm control: it may enhance myocardial contractility by activating intracellular signaling pathways (e.g., AMPK), improving ventricular ejection fraction and reducing cardiac workload. This dual action—stabilizing rhythm and supporting pump function—makes it a valuable adjunct in managing chronic heart conditions, especially when combined with conventional therapies. Notably, its natural origin reduces the risk of severe side effects often associated with synthetic anti-arrhythmic drugs, offering a safer option for long-term use in vulnerable populations.​

Treatment of Gastrointestinal Diseases: Targeting Root Causes of Mucosal Damage​

Berberine hydrochloride powder’s efficacy in gastrointestinal disorders arises from a synergistic combination of acid-suppressive, mucosal-protective, and regenerative effects. It directly inhibits the secretion of gastric acid by blocking histamine H2 receptors and reducing proton pump activity, thereby lowering gastric juice acidity—a critical factor in preventing further erosion of the gastric and duodenal mucosa in conditions like peptic ulcers.​

Equally important is its role in mucosal protection: it stimulates the synthesis of prostaglandins (e.g., PGE2), which enhance mucus production and strengthen the mucosal barrier, shielding underlying tissues from acid and digestive enzymes. For gastric ulcers, this protective action is complemented by its ability to promote angiogenesis and accelerate epithelial cell proliferation, speeding up the healing of ulcerated lesions. Additionally, its mild anti-inflammatory properties reduce mucosal edema and inflammation in chronic gastritis, while its indirect inhibition of Helicobacter pylori (a major cause of ulcers) further supports long-term recovery. Together, these mechanisms make it effective not only in healing active ulcers but also in preventing recurrence, particularly in patients with persistent acid-related disorders.

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Applications of Berberine Hydrochloride Powder

1.Pharmaceutical Field: Dual Roles in Anti-infection and Metabolic Regulation​

Berberine hydrochloride powder plays a significant role in the pharmaceutical industry. It has a marked inhibitory effect on pathogenic microorganisms such as bacteria and fungi, making it a commonly used pharmaceutical ingredient in the treatment of intestinal infections (e.g., bacillary dysentery, enteritis). By interfering with the metabolic processes of pathogenic microorganisms, it effectively prevents the reproduction of pathogens and alleviates symptoms like diarrhea and abdominal pain. Meanwhile, recent studies have found that it can also regulate glucose and lipid metabolism, helping to improve blood sugar levels in patients with type 2 diabetes. It enhances insulin sensitivity by activating the AMPK signaling pathway, becoming a potential option for the auxiliary treatment of metabolic diseases.​

2. Health Product Industry: A Natural Boost for Intestinal Health and Immune Regulation​

In the health product sector, berberine hydrochloride powder is often made into capsules or tablets and used as an intestinal microecological regulator. It can promote the proliferation of beneficial intestinal bacteria (such as bifidobacteria), inhibit the excessive growth of harmful bacteria, maintain the balance of intestinal flora, and thereby improve digestive function. In addition, it has a certain immune-enhancing effect, which can stimulate the activity of immune cells and enhance the body's resistance. It is especially suitable for people with weak intestinal function or low immunity as a daily health supplement.​

3. Veterinary Medicine Field: A Powerful Tool for the Prevention and Treatment of Infectious Diseases in Livestock and Poultry​

Berberine hydrochloride powder is mostly used in veterinary medicine to prevent and treat intestinal infectious diseases in livestock and poultry, such as pullorum disease in chickens and colibacillosis in pigs. Compared with some chemical antibiotics, it is less likely to produce drug resistance and can reduce drug residues in animals, conforming to the development trend of green breeding. At the same time, in aquaculture, it can be used to prevent and treat bacterial enteritis, gill rot disease, etc. in fish, improving the survival rate of aquaculture.​

4. Cosmetics Field: A Natural Ingredient with Anti-inflammatory and Antioxidant Properties​

With the popularity of natural ingredients in cosmetics, berberine hydrochloride powder has gradually attracted attention due to its anti-inflammatory and antioxidant properties. In skin care products, it can inhibit Propionibacterium acnes.​

5. Scientific Research Field: A Valuable Tool for Mechanism Exploration​

Berberine hydrochloride powder is also widely used in scientific research. It serves as an important research tool in studies related to microbiology, pharmacology, and metabolomics. Researchers use it to explore the interaction mechanisms between drugs and microorganisms, the regulatory pathways of metabolic diseases, etc., providing a basis for the development of new drugs and the improvement of existing treatment schemes. Its clear chemical structure and relatively definite biological activity make it a commonly used substance in laboratory studies.

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Hydrochloride Powder Advantages

1. Premium Natural Sourcing: The Foundation of Kintaihealth®’s Purity Commitment​

Kintaihealth® Berberine Hydrochloride Powder starts with meticulous selection of raw materials, sourced exclusively from organically cultivated Coptis chinensis rhizomes in ecologically pristine regions. This ensures the alkaloid content remains uncompromised by pesticides or heavy metals, aligning with the brand’s "nature-first" ethos. The extraction process uses cold-press technology to preserve the compound’s molecular integrity—unlike heat-based methods that can degrade bioactivity—resulting in a powder with a berberine concentration exceeding 97%. This high purity not only enhances therapeutic efficacy but also minimizes the risk of allergic reactions, making it suitable for long-term use in dietary supplements and pharmaceutical formulations.​

2. Science-Backed Formulation: Precision That Defines Kintaihealth®’s Reliability​

At the core of Kintaihealth®’s advantage lies its integration of traditional knowledge with modern scientific rigor. The powder undergoes triple-layer quality testing: first, phytochemical screening to verify alkaloid profile; second, microbial load assessment to ensure sterility; and third, stability testing under varying temperature and humidity conditions. This stringent protocol guarantees consistent potency across batches—a critical factor for healthcare providers relying on predictable dosages. Additionally, Kintaihealth®’s proprietary micronization process reduces particle size to 5-10μm, enhancing solubility and bioavailability. This means the powder dissolves rapidly in both aqueous and lipid-based solutions, ensuring faster absorption in the gastrointestinal tract and more effective delivery to target tissues, from intestinal mucosa to cardiac cells.​

3. Versatile Application: Adaptability to Diverse Health Scenarios​

Kintaihealth® Berberine Hydrochloride Powder stands out for its seamless integration into multiple product categories, reflecting the brand’s understanding of varied market needs. In pharmaceuticals, it serves as an active ingredient in anti-diarrheal and anti-inflammatory formulations, leveraging its broad-spectrum antibacterial action. In nutraceuticals, it is formulated into easy-to-consume capsules for daily gut health maintenance, with dosage guidelines tailored to different age groups. Even in veterinary care, its low toxicity profile makes it ideal for preventing intestinal infections in livestock without causing residue issues. This versatility is supported by Kintaihealth®’s provision of customizable particle sizes and solubility grades, allowing manufacturers across industries to adapt the powder to their specific production requirements—from fast-dissolving tablets to sustained-release formulations.​

Why choose Hydrochloride Powder by Kintaihealth®?

1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Hydrochloride Powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

OEM and ODM Services

KINTAI is a professional manufacturer and supplier of Berberine hydrochloride powder. We give OEM and ODM administrations to meet the particular necessities of our clients. Our examination community, creation base, and gear are all cutting-edge, guaranteeing excellent items. We have different licenses and accreditations, and our quality confirmation framework ensures the security and viability of our items. For more information, please contact us at info@kintaibio.com.

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