Tetrahydrocurcumin Powder

Plant Source: Turmeric (curcuma longa) rhizome
CAS No: 36062-04-1
Specification: 98% Tetrahydrocurcumin
Appearance: White powder
Test Method: HPLC
Lead time: 1-3 days
Storage: cool, dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Payment: Multiple terms acceptable like T/T, L/C, DA
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiation-qualified product.
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  • 24/7 Customer Service

Product Introduction

Product Details


Xi'an Kintaihealth® is a leading producer of premium Tetrahydrocurcumin Powder, delivering pharmaceutical-grade quality with purity consistently exceeding 98% through advanced extraction and purification technologies. As a key hydrogenated derivative of curcumin (CAS: 36071-41-3), Tetrahydrocurcumin exists in its core bioactive form, ensuring high bioavailability and stability for diverse applications. Our GMP-compliant production process guarantees superior stability and reliability for use in anti-aging functional foods, dietary supplements for oxidative stress relief, cosmeceuticals for skin brightening, and pharmaceutical research focused on anti-inflammatory and neuroprotective formulations.If you want to buy Tetrahydrocurcumin Powder,you can contact me : herb@kintaibio.com

 

  What is Tetrahydrocurcumin Powder?  

Tetrahydrocurcumin Powder(THC) is hydrogenated from curcumin isolated from the rhizome of turmeric, and is a natural cosmetic whitening raw material. Tetrahydrocurcumin has strong activity of inhibiting tyrosinase, can effectively inhibit the generation of free radicals and remove free radicals in the body, has obvious antioxidant effect, can resist skin aging, fade stains, darkness and so on.

Tetrahydrocurcumin Powder

Chemical & Physical Properties

CAS Number 36062-24-1 Density 1.222 g/cm3
Molecular Formula C21H24O6 Molecular Weight 372.41
Melting Point 95-97 ℃ Boiling Point 564.1±45.0 ℃ (Predicted)
Solubleness Soluble in DMSO (slight), methanol (slight, heated) Test Method HPLC

Structure of Tetrahydrocurcumin

 

  Kintai Oleanolic Acid Powder Advantages  

High Potency & Clinically Proven Efficacy : Our Tetrahydrocurcumin Powder is available in Pharmaceutical Grade (≥98% purity) and Nutraceutical Grade (≥95% purity), rigorously analyzed by HPLC to ensure outstanding antioxidant, anti - inflammatory, and photostable properties. Every batch guarantees consistent bioactivity, enabling the development of premium - grade products.

Multi - Industry Application :

• Nutraceuticals : Oxidative stress reducer, supports liver health, and aids in joint comfort for dietary supplements.

• Cosmetics : Enhances skin brightness, reduces melanin formation, and promotes a even complexion as a key ingredient in anti - pigmentation skincare formulations.

• Pharmaceuticals : Potential applications in research for neuroprotective, anti - arthritic, and metabolic syndrome - related therapies.

Strict Quality Control : Manufactured in a GMP - compliant facility, our Tetrahydrocurcumin Powder offers complete traceability, accompanied by detailed COA, MSDS, and comprehensive testing for heavy metals, residual solvents, and microbial contaminants.

Interested? We’d Love to Send You a Sample!

  Tetrahydrocurcumin Powder Production Process  

1. Raw Material Preparation

High-purity curcumin (≥98% by HPLC) is selected as the raw material.

2. Hydrogenation Reaction

In a high-pressure reactor, curcumin undergoes hydrogenation with hydrogen gas using a catalyst (e.g., palladium on carbon) at 60–100°C and 2–5 MPa, forming tetrahydrocurcumin.

3. Purification

The reaction mixture is filtered to remove the catalyst, then purified via column chromatography (e.g., silica/alumina) or crystallization to eliminate unreacted curcumin and byproducts.

4. Drying & Milling

The purified tetrahydrocurcumin is dried via vacuum or spray drying, then milled and sieved (80–100 mesh) to achieve uniform powder.

5. Quality Control

HPLC verifies purity ≥98%, with additional testing for heavy metals (lead, arsenic), residual solvents (methanol, ethanol), and microbial contaminants.

 

  Tetrahydrocurcumin Powder Benefits  

1.Whitening effect: The whitening effect of tetrahydrocurcumin is better than that of common whitening ingredients such as arbutin. It can effectively slow down the generation of melanin, remove the free radicals that have been formed and inhibit the further generation of free radicals, break the free radical chain reaction caused by damage to the skin, so as to lighten the skin color and achieve whitening effect.

2.Anti-inflammatory and antibacterial: Tetrahydrocurcumin Powder has anti-inflammatory and antibacterial effects, can repair skin inflammation and damage, and has a significant effect on the treatment of mild burns, skin inflammation and acne scars.

3.Anti-aging: Tetrahydrocurcumin can inhibit the proliferation of free radicals and the oxidation of fat, so it can be added to cosmetics, extend the shelf life of cosmetics, and effectively combat skin aging.

Tetrahydrocurcumin's Anti-Aging Effect.

  Tetrahydrocurcumin Applications  

Cosmetics: Tetrahydrocurcumin is widely used in various skin care products for whitening, freckle removal and antioxidant, such as creams, lotions and serums.
Pharmaceutical products: Can be added to hemostasis, anti-inflammatory sterilization and other drugs.
Food industry: Can be used as seasoning or food additive.

Applications of Tetrahydrocurcumin

Interested? We’d Love to Send You a Sample!

 

  Tetrahydrocurcumin Powder Dosage  

Application

Target Use/Population

Recommended Dosage

Precautions

Dietary Supplement

Antioxidant support, liver health, joint comfort

Adults: 100–300 mg daily, divided into 1–2 doses (based on pure tetrahydrocurcumin)

- Take with meals to enhance absorption
- Avoid high doses if sensitive

Cosmetics (Topical)

Skin brightening, anti-pigmentation, UV protection

Addition concentration: 0.5%–2% (e.g., serums, creams), apply 1–2 times daily

- Patch test for sensitive skin
- Store away from light to maintain stability

Medical Research

Neuroprotection, anti-arthritic studies

Research dosage: 500–1,000 mg daily (under professional supervision)

- Not for clinical use without medical approval

Special Populations

Pregnant/lactating women, children (<14 years old)

Safety data insufficient; not recommended for use

- Avoid use in individuals with liver disorders

  Safety of KINTAI’S Tetrahydrocurcumin Powder  ​​​​​​​

1. Allergic Reactions and Sensitivities

Tetrahydrocurcumin powder is generally well-tolerated by most individuals. However, as a hydrogenated derivative of curcumin, those with known allergies to turmeric or phenolic compounds may be susceptible to adverse reactions. An initial sensitivity test is recommended, especially when incorporating tetrahydrocurcumin into new dietary supplements or formulations. Discontinue use immediately and seek medical advice if symptoms such as skin rash, itching, swelling, or respiratory distress occur.

2. Safety and Toxicity Research

General Safety Limits :

No universally standardized upper limit exists for tetrahydrocurcumin intake. Clinical trials typically use doses ranging from 100–300 mg/day without significant adverse effects. Doses exceeding 500 mg/day may increase the risk of mild gastrointestinal symptoms (e.g., bloating, diarrhea).

Toxicity Data :

Animal studies (rats) indicate the acute oral LD₅₀ of tetrahydrocurcumin exceeds 2,000 mg/kg, indicating low acute toxicity. Long-term studies (up to 12 months) at doses of 200–400 mg/day report no severe systemic toxicity.

Purity and Quality :

Kintai’s Tetrahydrocurcumin Powder is produced using advanced hydrogenation and purification technologies, achieving pharmaceutical-grade purity of ≥98% (verified by HPLC). Rigorous testing ensures minimal contaminants, including heavy metals (e.g., lead, arsenic) and residual solvents, meeting global quality standards.

3. International Compliance

EU Regulations : Tetrahydrocurcumin is recognized as a safe ingredient for use in food supplements and nutraceuticals within the EU, provided it meets required purity and safety criteria.

US FDA : The FDA has not established specific regulations for tetrahydrocurcumin as a dietary supplement ingredient. However, when used in pharmaceuticals or food additives, it must comply with Good Manufacturing Practice (GMP) guidelines.

Asia : In countries such as China, Japan, and South Korea, tetrahydrocurcumin is approved for use in dietary supplements, functional foods, and cosmeceuticals, adhering to local purity and safety standards.

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OEM and ODM Services

KINTAI offers comprehensive OEM and ODM services, acclimatizing Tetrahydrocurcumin Powder to meet specific conditions. Our devoted platoon collaborates with guests to produce unique products, icing satisfaction and request competitiveness. You can contact us by herb@kintaibio.com for more details.

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