What is Diosmin Powder used for?
2025-05-26 09:32:02
Diosmin Powder is a powerful flavonoid compound derived from natural plant sources, primarily through the semi-synthesis of hesperidin extracted from citrus fruits. As an intravenous active drug with remarkable therapeutic properties, Diosmin Powder has gained significant recognition in the medical community for its efficacy in treating various circulatory and vascular conditions. This bioactive compound functions by promoting blood and lymphatic circulation while enhancing venous tension, making it an excellent solution for addressing hemorrhoids, venous lymphatic insufficiency, and related disorders. KINTAI Biotech Inc., a leading manufacturer of herbal extracts and pharmaceutical intermediates, provides high-quality Diosmin Powder with a purity of 96%, ensuring optimal effectiveness for various healthcare applications.

Therapeutic Benefits of Diosmin Powder
Vascular Health Enhancement
Diosmin Powder plays a crucial role in maintaining and improving vascular health. The compound, with its molecular formula C₂₈H₃₂O₁₅ and molecular weight of 608.54, demonstrates remarkable properties that benefit the vascular system. One of the most significant advantages of Diosmin Powder is its ability to enhance venous tension, even under challenging conditions such as high temperatures. This unique capability surpasses similar compounds like rutin, making it particularly effective for vascular applications. By improving venous wall tension, Diosmin Powder helps optimize venous return and significantly reduces venous pressure, addressing the root causes of many vascular issues. KINTAI Biotech ensures their Diosmin Powder maintains consistency in quality through rigorous testing using HPLC methods, guaranteeing that healthcare professionals and patients receive a reliable product that meets international standards for treating vascular conditions.
Microcirculation Improvement
The efficacy of Diosmin Powder in improving microcirculation represents one of its most valuable therapeutic benefits. This brownish-yellow powder, almost insoluble in water and ethanol but soluble in dimethyl sulfoxide and dilute alkaline solutions, works at the microscopic level of circulation to bring about significant health improvements. Diosmin Powder effectively reduces blood viscosity, allowing blood to flow more freely through the smallest vessels in the body. This reduction in viscosity leads to an increased red blood cell flow rate, ensuring that oxygen and nutrients reach tissues more efficiently. Additionally, the powder helps reduce microcirculatory congestion, preventing the buildup of pressure and fluid that can lead to discomfort and tissue damage. KINTAI Biotech's Diosmin Powder, produced under strict GMP and ISO certifications, delivers consistent results in microcirculation improvement, making it a trusted choice for healthcare practitioners looking to address conditions related to poor microcirculation, such as chronic venous insufficiency and associated symptoms.
Lymphatic System Support
Diosmin Powder provides exceptional support for the lymphatic system, a critical but often overlooked component of circulatory health. The lymphatic system plays a vital role in immune function and fluid balance, and Diosmin Powder enhances its efficiency through multiple mechanisms. Primarily, Diosmin Powder increases lymphatic drainage speed, facilitating the movement of lymph fluid through the body's complex network of lymphatic vessels. This acceleration helps prevent fluid buildup in tissues, a common cause of swelling and discomfort. Furthermore, the powder stimulates lymphatic vessel contraction, improving the natural pumping mechanism that moves lymph through the body. These combined effects result in accelerated return of interstitial fluid to circulation, improved lymphatic return, and significant reduction in edema. KINTAI Biotech's pharmaceutical-grade Diosmin Powder, with a melting point of 277-278°C and strictly tested for purity, delivers reliable lymphatic system support, making it invaluable for patients suffering from lymphatic insufficiency and related conditions like post-surgical edema or lymphedema.

Clinical Applications of Diosmin Powder
Hemorrhoid Treatment and Management
Diosmin Powder stands out as an effective solution for the treatment and management of hemorrhoids, a common condition affecting millions worldwide. This powerful flavonoid compound addresses hemorrhoidal issues through multiple pathways, making it a preferred choice among healthcare professionals. When administered for acute attacks of hemorrhoids, Diosmin Powder quickly alleviates uncomfortable symptoms including anal dampness, persistent itching, blood in the stool, and intense pain caused by inflamed hemorrhoidal tissues. The compound works by strengthening vascular walls, reducing inflammation, and improving blood flow in the affected area, thereby addressing both symptoms and underlying causes. KINTAI Biotech's pharmaceutical-grade Diosmin Powder (CAS No: 520-27-4) provides consistent relief for hemorrhoid sufferers, with its 96% purity ensuring maximum efficacy. The powder's ability to enhance venous tension specifically helps reduce the pressure in hemorrhoidal veins, preventing further swelling and promoting healing of already inflamed tissues. For patients seeking long-term management of recurring hemorrhoids, regular use of Diosmin Powder has shown promising results in reducing the frequency and severity of flare-ups.
Chronic Venous Insufficiency Treatment
Diosmin Powder has emerged as a cornerstone treatment for chronic venous insufficiency, a condition characterized by inadequate functioning of venous valves that leads to blood pooling in the lower extremities. This flavonoid compound effectively addresses the multifaceted nature of venous insufficiency through its comprehensive action on the vascular system. Patients suffering from symptoms such as heaviness and pain in the lower limbs, persistent soreness, and morning discomfort find significant relief through Diosmin Powder treatment. The powder's ability to enhance venous tone and reduce capillary permeability directly targets the physiological deficiencies causing these symptoms. KINTAI Biotech's high-quality Diosmin Powder, produced under strict GMP, ISO9001:2016, and ISO22000:2006 certifications, delivers consistent therapeutic benefits for venous insufficiency patients. The compound's boiling point of approximately 926.8±65.0 °C ensures its stability during processing and storage, maintaining its efficacy for clinical applications. Healthcare providers particularly value Diosmin Powder for its ability to improve venous return in patients with compromised venous function, leading to reduced edema and improved quality of life for those suffering from this chronic condition.
Cardiovascular Health Promotion
Diosmin Powder offers substantial benefits for overall cardiovascular health, extending beyond its well-known applications for venous conditions. This versatile compound contributes to cardiovascular wellness through multiple mechanisms that support heart health and circulatory function. Research has shown that Diosmin Powder can be effectively utilized in the treatment of cardiovascular conditions such as arteriosclerosis and hypertension, helping to maintain healthy blood vessels and regulate blood pressure. The powder's antioxidant properties protect vascular tissues from oxidative damage, while its anti-inflammatory effects reduce vascular inflammation, a key factor in many cardiovascular diseases. KINTAI Biotech's pharmaceutical-grade Diosmin Powder, with a density of approximately 1.68±0.1 g/cm³, provides consistent dosing for cardiovascular applications. Additionally, the powder improves symptoms caused by venous blood and lymphatic circulation disorders, including soft tissue swelling, numbness of the limbs, and chronic pain. Healthcare professionals increasingly recommend Diosmin Powder as part of an integrated approach to cardiovascular health, especially for patients with multiple risk factors or existing conditions that affect their vascular system.
Production and Quality Assurance of Diosmin Powder
Manufacturing Process Excellence
The production of premium Diosmin Powder requires sophisticated manufacturing processes that KINTAI Biotech has perfected over its decade-long service to the global health industry. The journey begins with the careful selection of high-quality natural plant materials rich in hesperidin, the precursor compound for Diosmin synthesis. Through a precise semi-synthesis process, hesperidin is transformed into pharmaceutical-grade Diosmin with 96% purity. This complex manufacturing sequence involves multiple steps of extraction, purification, and quality control to ensure consistent potency and purity in every batch. KINTAI's manufacturing facilities employ state-of-the-art equipment and advanced technologies that maintain optimal conditions throughout the production cycle. The company's commitment to manufacturing excellence is evident in their adherence to Good Manufacturing Practices (cGMP), ensuring that their Diosmin Powder meets international quality standards. Each production batch undergoes rigorous in-process testing to monitor quality parameters at every stage, allowing for immediate adjustments if necessary. This meticulous approach to manufacturing results in a Diosmin Powder that consistently demonstrates the expected pharmacological effects for vascular health, making KINTAI a trusted supplier for pharmaceutical companies, health food manufacturers, and cosmetic producers worldwide.
Quality Testing and Certification
KINTAI Biotech implements comprehensive quality testing procedures for their Diosmin Powder, ensuring that every batch meets stringent specifications before reaching customers. The testing begins with raw material verification and continues throughout the manufacturing process until final product release. Using High-Performance Liquid Chromatography (HPLC) as the primary analytical method, KINTAI's quality control team verifies that each batch of Diosmin Powder achieves the specified 96% purity level. Beyond purity testing, the powder undergoes thorough physical and chemical characterization, including verification of its brownish-yellow appearance, melting point (277-278°C), density, molecular weight, and solubility properties. KINTAI's quality assurance extends beyond internal testing to include certifications from recognized international bodies. The company proudly maintains multiple certifications including GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER, and HALAL, demonstrating their commitment to quality across various markets and regulatory frameworks. These certifications require regular audits and continuous compliance with evolving standards, ensuring that KINTAI's Diosmin Powder consistently meets the highest quality benchmarks. For healthcare professionals and manufacturers using Diosmin Powder in their formulations, these rigorous testing protocols and certifications provide confidence in the product's safety, efficacy, and batch-to-batch consistency.
Customization and Formulation Services
KINTAI Biotech distinguishes itself in the market by offering extensive customization and formulation services for Diosmin Powder, allowing clients to develop products tailored to their specific requirements. As a leading OEM and ODM service provider, KINTAI collaborates closely with customers to create customized formulations that maximize the therapeutic benefits of Diosmin Powder while meeting market demands. Their expert team guides clients through every step of product development, from initial concept to final formulation, ensuring that the resulting product aligns perfectly with the intended application and target audience. The company's formulation capabilities extend beyond basic powder production to include various delivery formats such as granules, capsules, and tablets, providing flexibility in how Diosmin Powder can be administered or incorporated into finished products. KINTAI's formulation specialists can adjust parameters such as dissolution rate, bioavailability, and stability to optimize product performance for specific therapeutic applications. Additionally, the company offers comprehensive support services including product concept development, identification of unique selling points, rigorous testing, packaging solutions, assistance with customs clearance, and guidance on regulatory compliance across multiple markets. This end-to-end approach to customization and formulation makes KINTAI an ideal partner for companies looking to incorporate the benefits of Diosmin Powder into innovative healthcare products, nutritional supplements, or pharmaceutical formulations.

Conclusion
Diosmin Powder stands as a versatile and effective natural compound with significant applications in vascular health, hemorrhoid treatment, and venous insufficiency management. Its ability to enhance venous tension, improve microcirculation, and support lymphatic return makes it a valuable therapeutic option for healthcare professionals and patients alike. KINTAI Biotech, with its decade of experience and commitment to quality, provides pharmaceutical-grade Diosmin Powder that meets international standards through GLP and cGMP compliance.
Are you looking to incorporate high-quality Diosmin Powder into your healthcare formulations or seeking customized solutions for your specific needs? KINTAI Biotech offers complete professional solutions from concept to finished product, including OEM and ODM services for powders, granules, capsules, and tablets. Contact us today at info@kintaibio.com to discover how our expertise can help you develop superior products that make a difference in people's lives.
References
1. Martinez-Zapata MJ, Vernooij RW, Uriona Tuma SM, et al. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2016;4(4):CD003229.
2. Lyseng-Williamson KA, Perry CM. Micronised purified flavonoid fraction: a review of its use in chronic venous insufficiency, venous ulcers and haemorrhoids. Drugs. 2003;63(1):71-100.
3. Nicolaides AN. Investigation of chronic venous insufficiency: A consensus statement. Circulation. 2000;102(20):E126-E163.
4. Ibegbuna V, Nicolaides AN, Sowade O, et al. Venous elasticity after treatment with Daflon 500 mg. Angiology. 1997;48(1):45-49.
5. Katsenis K. Micronized purified flavonoid fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Curr Vasc Pharmacol. 2005;3(1):1-9.
6. Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-S56.
