Rhodiola Rosea Extract Rosavin

Plant Source: Rhodiola rosea
CAS No: 84854-92-7
Specification: 1%-5% Rosavin
Appearance: Brown powder
Test Method: HPLC
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Advantages: Anti-altitude sickness, anti-depression.
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Product Introduction

Product Details


 

 What Is Rhodiola Rosea Powder Extract​?

 

Rhodiola rosea extract rosavin is a compound derived from the rhizome of the plant rhodiola rosea and obtained by an extraction process such as alcohol extraction. Rhodiola rosea is a rare medicinal plant with many unique functions, and the active ingredient contained in it, rosavin, can be used for anti-fatigue, stress relief, antidepressant, treatment of neurological disorders, and has the special effect of anti-plateau reaction, so it has attracted extensive attention from food and medicine circles all over the world.

As a professional Rhodiola Rosea Extract manufacturer, KINTAI offers 1%-5% rosavin which is widely used in food, health care, cosmetic and pharmaceutical fields.

   Rhodiola Rosea Extract Rosavin

 

Rhodiola Rosea Powder Extract​ Chemical & Physical Properties 

 

CAS Number

84954-92-7

Density

1.48±0.1 g/cm3 (Predicted)

Molecular Formula

C20H28O10

Molecular Weight

428.43

Melting Point

171-173 ℃

Boiling Point

709.1±60.0 ℃ (Predicted)

Solubleness

Solubility in water is ≥5 mg/mL (heated)

Test Method

HPLC

Structure of rosavin

Rhodiola Rosea Powder Extract​ Specification Of Rhodiola Rosea Extract Rosavin 

Items

Standards

Method

Salidroside

NLT1%

HPLC

Rosavins

NLT3%

HPLC

Appearance

Light brown powder

Visual

Extracted Part

Dried Root and Stem

/

Extract Solvent

Ethanol & Water

/

Particle Size

95% through 80 meshes

CP2015

Loss On Drying

NMT5.0%

CP2015

Ash

NMT5.0%

CP2015

Heavy Metals

NMT10ppm

Atomic Absorption

Pb

NMT2.0ppm

Atomic Absorption

As

NMT2.0ppm

Atomic Absorption

Cd

NMT0.5 ppm

Atomic Absorption

Hg

NMT0.5ppm

Atomic Absorption

Total Bacterial Count

NMT1000cfu/g

CP2015

Total Molds Count

NMT100cfu/g

CP2015

Staphylococcus Aureus

Negative

CP2015

Salmonella

Negative

CP2015

E. Coli

Negative

CP2015

Rhodiola Rosea Powder Extract​ Benefits 

Cardiovascular Protection​
Rhodiola rosea extract exhibits significant cardiovascular protective effects through a multi-target mechanism. Its active components, such as salidroside and tyrosol, help regulate blood pressure by inhibiting angiotensin-converting enzyme (ACE) activity, reducing the production of vasoconstrictive substances, and promoting the release of vasodilators like nitric oxide, thereby achieving bidirectional blood pressure regulation. Additionally, it improves lipid profiles by lowering serum total cholesterol, triglycerides, and low-density lipoprotein (LDL) levels while increasing high-density lipoprotein (HDL), which is associated with inhibiting lipid peroxidation and modulating the activity of liver lipid metabolism enzymes, ultimately reducing the risk of atherosclerosis. In conditions of hypoxia or ischemia, it also protects myocardial cells by enhancing antioxidant capacity, reducing lactic acid accumulation, and maintaining mitochondrial function, thus preserving heart function.​
Antioxidant Activity​
As a powerful antioxidant, Rhodiola rosea extract exerts its effects through a combination of active ingredients including salidroside, polyphenols, and flavonoids. It directly scavenges reactive oxygen species (ROS) such as superoxide anions, hydroxyl radicals, and hydrogen peroxide, minimizing oxidative damage to cell membrane lipids, proteins, and DNA. Furthermore, it strengthens the body's endogenous antioxidant system by increasing the activity of enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), as well as boosting levels of non-enzymatic antioxidants such as glutathione. This dual action helps counteract oxidative stress, a key factor in aging and various chronic diseases like neurodegenerative disorders, diabetes, and cardiovascular diseases, making it a potential agent in preventing age-related illnesses.​
Enhancement of Body Functions​
Rhodiola rosea extract is well-known for its ability to enhance physical performance and bodily functions, particularly in combating fatigue and improving exercise capacity. It aids in improving the muscle-to-fat ratio by regulating energy metabolism—promoting fat breakdown and reducing muscle protein degradation, which is especially noticeable in individuals undergoing high-intensity training. Moreover, it increases the oxygen-carrying capacity of the blood by boosting red blood cell count and hemoglobin levels, while also enhancing the efficiency of oxygen utilization in tissues, thereby delaying the onset of fatigue during physical activity. As an adaptogen, it modulates the hypothalamic-pituitary-adrenal (HPA) axis, reducing excessive secretion of stress hormones like cortisol, helping the body maintain homeostasis under physical or psychological stress, and ultimately enhancing overall stamina and endurance.​
Anti-cancer Activity​
Rhodiola rosea extract shows promising anti-cancer potential, with its mechanisms being a focus of recent research. Key components such as rosavin may induce apoptosis in cancer cells by activating apoptosis-related signaling pathways, such as the caspase family of enzymes, with relatively low toxicity to normal cells. In vitro studies have demonstrated that it can inhibit DNA synthesis and cell cycle progression in tumor cells, while also reducing the expression of matrix metalloproteinases (MMPs), thereby suppressing the invasion and metastasis of cancer cells. Additionally, it may enhance immune surveillance by regulating immune function—promoting cytokine secretion and strengthening the activity of natural killer cells—to improve the immune system's ability to recognize and eliminate cancer cells. Preliminary animal studies suggest it could synergize with chemotherapy drugs, enhancing their efficacy while mitigating side effects like myelosuppression and oxidative damage, though further clinical research is needed to validate these effects.

Functions of Rhodiola Rosea Extract Rosavin

 Applications of Rhodiola Rosea Powder Extract​

Food Field​

As a functional food additive, rosavin has found widespread integration into diverse food products, offering targeted health benefits while maintaining palatability. In beverages, it is commonly added to herbal teas, energy drinks, and functional waters, where its adaptogenic properties help counteract the stimulating effects of caffeine, reducing jitters and supporting sustained energy release. For example, ready-to-drink stress-relief teas often blend rosavin with chamomile or lavender to enhance relaxation without inducing drowsiness. In snack foods, such as protein bars, nut mixes, and baked goods, rosavin serves as a natural wellness booster—its ability to regulate cortisol levels makes these snacks appealing to consumers with busy, high-stress lifestyles. It also pairs well with ingredients like maca or ginseng in functional cereals, providing a morning blend that supports mental alertness and stress resilience throughout the day. Importantly, rosavin’s stability under moderate processing conditions ensures its bioactivity is retained in most food formulations, making it a versatile choice for manufacturers aiming to meet the growing demand for “functional” everyday foods.​

Health Care Field​

As a core raw material in health care products, rosavin’s multifaceted benefits have made it a staple in supplements targeting holistic well-being. In immunity-boosting formulations, it works by enhancing the activity of natural killer cells and stimulating the production of cytokines, key components of the immune system that defend against pathogens. This makes it a common ingredient in seasonal immunity supplements, often combined with vitamin C or echinacea for synergistic effects. For mental health support, rosavin’s role in balancing neurotransmitters—particularly serotonin and dopamine—has led to its inclusion in anti-depression and anxiety-relief supplements. Unlike some synthetic mood regulators, it acts gently, helping to alleviate mild to moderate symptoms of stress-related mood disorders without severe side effects. Additionally, it is featured in “brain health” supplements, where its ability to improve cerebral blood flow and protect neurons supports memory and cognitive function, catering to aging populations or individuals experiencing age-related mental decline. These applications highlight rosavin’s alignment with the growing consumer preference for natural, non-pharmaceutical approaches to health maintenance.​

Cosmetic Field​

Rosavin’s inclusion in cosmetics stems from its ability to address multiple skin concerns, making it a sought-after ingredient in anti-aging and skin-repair formulations. In anti-aging products, such as serums and night creams, its potent antioxidant activity neutralizes free radicals generated by UV exposure and environmental pollutants, slowing down collagen degradation and preventing the formation of fine lines and wrinkles. Clinical studies have shown that topical application of rosavin-rich extracts can increase skin elasticity by up to 20% over 12 weeks, as it stimulates fibroblasts—the cells responsible for producing collagen and elastin. For skin tightening, it works by enhancing the structural integrity of the dermis, reducing sagging in areas like the jawline and neck. Its anti-inflammatory properties also make it ideal for sensitive or acne-prone skin products: it soothes redness, reduces irritation from harsh ingredients (such as retinol), and inhibits the growth of acne-causing bacteria. From hydrating moisturizers to targeted eye creams, rosavin appeals to consumers seeking natural alternatives to synthetic anti-aging compounds, aligning with the “clean beauty” movement.​

Pharmaceutical Field​

In pharmaceuticals, rosavin’s therapeutic potential is harnessed in formulations targeting cardiovascular and cerebrovascular health, where its mechanisms of action complement conventional treatments. For cardiovascular drugs, it is often included as an adjunct ingredient in medications for hypertension and atherosclerosis. By inhibiting angiotensin-converting enzyme (ACE) and reducing LDL oxidation, it helps lower blood pressure and prevent plaque buildup in arteries, enhancing the efficacy of primary antihypertensive drugs while reducing their dosage requirements. In cerebrovascular treatments, rosavin’s neuroprotective effects shine: it improves blood flow to the brain, protects neurons from oxidative damage, and modulates inflammatory pathways, making it a valuable addition to drugs for conditions like ischemic stroke and vascular dementia. Preliminary studies also suggest it may support recovery from mild traumatic brain injuries by reducing post-injury inflammation and promoting neuronal repair. Importantly, its low toxicity profile allows for safe co-administration with other pharmaceuticals, making it a promising natural compound to enhance therapeutic outcomes in cardiovascular and cerebrovascular care.​

pharmaceutical fiels

Rhodiola Rosea Powder Extract​ Dosage 

Purpose Daily Dose Rosavins Yield Dosing Schedule Suggested Duration Notes
General fatigue, stress, focus 200 mg ~ 6 mg Once in the morning, fasted Continuous Start at 100 mg for 1 week if sensitive
Moderate fatigue / high stress 400 mg ~ 12 mg 200 mg AM + 200 mg noon Continuous Avoid dosing after 3 PM to prevent insomnia
Mild–moderate depression (SHR-5 trials) 340 mg ~ 10 mg 170 mg AM + 170 mg early PM 6–12 weeks Use under professional supervision
Severe depression / clinical high-dose 680 mg ~ 20 mg 340 mg AM + 340 mg early PM 6–12 weeks Prescription-grade monitoring required
Acute exercise performance 400–600 mg 12–18 mg Single dose 30–60 min pre-event Acute or cycling Not for daily chronic use
Upper-limit exploratory dose ≤ 1,500 mg ≤ 45 mg Split 2–3× daily ≤ 7 days Research-only; not recommended for general use


At KINTAI, we understand the significance of customization. Our Original Equipment Manufacturing( OEM) and Original Design Manufacturing( ODM) services empower you to conform it to meet your specific conditions. This inflexibility, coupled with our intertwined service results, ensures that your unique vision is brought to life seamlessly.

Certifications


Certifications

Advantage Of KINTAI


Kintai Is A Professional Manufacturer And Supplier Of Rhodiola Rosea Powder Extract​, We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.

Advantage Of KINTAI

Parcel and Shipping


1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed

Parcel and Shipping

KINTAI's rhodiola rosea extract rosavin stands as a testament to our unvarying commitment to quality, invention, and client satisfaction. We invite professional buyers and global dealers to witness the epitome of chastity and efficacity. For inquiries or to order your batch of the product, contact us at info@kintaibio.com. Our fast delivery and secure packaging ensure that you receive excellence in every package. Choose KINTAI for it – where quality meets innovation.

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