Buckeye Extract
CAS No: 20977-05-3
Specification: 98% sodium aescinate
Appearance: White powder
Test Method: HPLC
Lead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
Sample: Free sample available
Certifications: GMP, ISO9001:2015, ISO22000:2008, HACCP, KOSHER and HALAL
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiation-qualified product.
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
As A Leading Supplier Of Buckeye Extract Powder, Healthkintai® Takes Pride In Offering Premium-grade Products That Stand Out From Average Market Specifications. Our Buckeye Extract Powder Features 98% Aescin, Accurately Determined Via Titration, Ensuring Exceptional Potency And Consistency. Additionally, We Provide 98% Sodium Aescinate, Rigorously Tested Using Hplc For Precise Quantification, Meeting The Highest Standards Of Purity.Committed to excellence, Healthkintai® adheres to stringent international regulations and holds certifications including GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL. These credentials underscore our dedication to quality, safety, and compliance, making our products the trusted choice for global partners seeking reliability and superior performance.
What Is Buckeye Extract
Buckeye extract, also known as horse chestnut extract, is primarily extracted from the seeds of trees in the Aesculus genus. Common sources include Aesculus hippocastanum L., which is native to the Balkan Peninsula, and Aesculus chinensis Bunge, a tree species in China.The main active component of Buckeye extract is aescin. It has been used in traditional medicine to treat conditions such as hemorrhoids and varicose veins due to its effects of strengthening blood vessels and reducing vascular permeability.
| Product Name: | Sodium Aescinate |
| CAS No.: | 20977-05-3 |
| Catalog No.: | CFN99509 |
| Molecular Formula: | C54H84NaO23 |
| Molecular Weight: | 1124.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Aesculus hippocastanum L. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
Kintai Buckeye Extract Advantages
Superior Purity with Advanced Testing Methods
Kintai’s Buckeye extract, including 98% aescin (titration-tested) and 98% sodium aescinate (HPLC-verified), exceeds average market specifications. These rigorous, industry-leading testing techniques ensure precise potency and consistency, meeting the strictest quality demands for pharmaceutical, nutraceutical, and cosmetic applications.
Comprehensive Certifications for Global Compliance
Backed by a full suite of international certifications—GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL—Kintai’s products adhere to stringent safety and quality standards worldwide. This compliance simplifies market access across regions, making it a trusted choice for partners in diverse global markets.
Focus on Active Ingredient Efficacy
With a focus on the key bioactive components (aescin and sodium aescinate), Kintai’s extract is optimized for performance in vascular health and related applications. Its high-quality formulation ensures reliable therapeutic or functional benefits, supporting consistent results for manufacturers and end-users alike.
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Buckeye Extract Manufacture Processing
Raw Material Prep: Select high-quality horse chestnut seeds, clean, and crush into powder.
Extraction: Use ethanol/hydroalcoholic solvent to extract aescin from the powder, then filter to remove residues.
Concentration: Evaporate excess solvent under reduced pressure to concentrate the aescin-rich solution.
Purification: Refine via chromatography or precipitation to remove impurities.
Sodium Conversion: React purified aescin with sodium salts (e.g., NaOH) to form water-soluble sodium aescinate.
Final Processing: Filter, crystallize, and dry to obtain high-purity powder (verified by HPLC).
Quality Check: Test for potency, contaminants, and compliance with global standards.
Buckeye Extract Specifications
| Chemical name | Escin monosodium salt; Sodium β-aescin |
| CAS Registry Number | 20977-05-3 |
| Molecular formula | C₅₄H₈₃NaO₂₃ |
| Molecular weight | 1123.21 g mol⁻¹ |
| Appearance | White to off-white amorphous powder |
| Purity (HPLC) | ≥ 98 % |
| Loss on drying | ≤ 5 % |
| Residue on ignition | ≤ 0.5 % |
| Heavy metals | ≤ 20 ppm |
| Microbial limits | Total aerobic count ≤ 1000 cfu g⁻¹; Yeast & mould ≤ 100 cfu g⁻¹ |
| Solubility (25 °C) | DMSO: ≥ 100 mg mL⁻¹ (89 mM) |
| Storage (powder) | –20 °C, desiccated, protected from light |
| Storage (stock solutions) | –80 °C, 6 months or –20 °C, 1 month (sealed, inert atmosphere) |
| Use statement | Laboratory reagent / RUO – not for human consumption |
| I |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (89.03 mM) | |||
| Water | 100 mg/mL (89.03 mM) | |||||
| Ethanol | Insoluble | |||||
| In vivo (Add solvents to the product individually and in order) | Oral Administration | Clear solution | saline | |||
| 100.000mg/ml (89.03mM) | Taking the 1 mL working solution as an example, add 100 mg of this product to 1 ml of physiological saline (0.9% NaCL solution), mix evenly to make it clear, The mixed solution should be used immediately for optimal results. | |||||
| ≥5mg/ml | Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml. | |||||
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Homogeneous suspension |
CMC-NA | |||||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Buckeye Extract Benefits
Supports Vascular Health
Buckeye extract, rich in aescin and sodium aescinate, strengthens blood vessel walls, reduces permeability, and enhances microcirculation. This helps maintain healthy vascular function, making it valuable for addressing issues like swelling from poor circulation.
Anti-Inflammatory Properties
Its active compounds inhibit inflammatory mediators, helping reduce swelling, redness, and discomfort associated with conditions like edema or minor tissue inflammation. This makes it a natural choice for supporting post-injury recovery.
Aids Venous Disorder Management
Widely recognized for its role in managing venous issues, such as varicose veins and hemorrhoids, horse chestnut extract helps alleviate symptoms like pain, heaviness, and swelling by improving venous tone and reducing congestion.
Supports Post-Surgical Recovery
By reducing post-operative swelling and promoting fluid balance, it can aid in faster recovery and improved comfort for patients.
Skin Health Benefits
In cosmetic applications, its ability to enhance circulation and reduce puffiness makes it useful in products targeting under-eye bags, while its anti-inflammatory properties support overall skin wellness.
Vascular Health
Anti-Inflammatory
Post-Surgical Recovery
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Buckeye Extract Applications
Pharmaceutical Industry
horse chestnut extract, particularly sodium aescinate, is widely used in prescription and over-the-counter medications. It is formulated into injections, tablets, and ointments to treat venous disorders (e.g., varicose veins, hemorrhoids), reduce post-traumatic or post-surgical swelling, and improve vascular permeability.
Nutraceuticals and Dietary Supplements
In supplement form, it is often included in products targeting circulatory health. These supplements aim to support healthy blood flow, alleviate leg heaviness, and maintain venous function, appealing to individuals with active lifestyles or those prone to mild circulatory discomfort.
Cosmetics and Skincare
Added to creams, serums, and eye care products, buckeye extract leverages its anti-inflammatory and circulation-boosting properties. It helps reduce under-eye puffiness, soothe irritated skin, and enhance overall skin tone by promoting microcirculation.
Veterinary Medicine
Veterinary formulations utilize horse chestnut extract to address similar issues in animals, such as swelling from injuries or venous congestion in larger breeds. It is often included in topical gels or oral supplements for companion animals.
Sports and Recovery Products
In sports nutrition and post-workout formulations, it aids in reducing exercise-induced swelling and muscle soreness. This makes it a common ingredient in recovery drinks, topical sprays, or muscle rubs for athletes and fitness enthusiasts..
Pharmaceutical Aesculus hippocastanum L
Dietary Supplements Aesculus hippocastanum L
Cosmetics and Skincare Aesculus hippocastanum L
Why Choose Buckeye Extract By Healthkintai®?
1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Buckeye Extract powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.
OEM and ODM Services
At KINTAI, we understand the significance of customization. Our Original Equipment Manufacturing( OEM) and Original Design Manufacturing( ODM) services empower you to conform it to meet your specific conditions. This inflexibility, coupled with our intertwined service results, ensures that your unique vision is brought to life seamlessly.
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Certifications
Advantage Of KINTAI
KINTAI is a professional manufacturer and supplier of Buckeye extract Powder, We have our own research and development center, production base, and state-of-the-art equipment. With multiple patents and certifications, we guarantee the highest quality and safety of our products. We provide comprehensive OEM and ODM services, ensuring customized products and integrated solutions. With fast delivery and secure packaging, we are your trusted partner in choosing your product. For more information, please contact us at info@kintaibio.com.
Parcel and Shipping
1> 1KG/bag, 10KG/carton, 25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost; professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed
In conclusion, KINTAI's Buckeye extract Powder stands as a testament to our unvarying commitment to quality, invention, and client satisfaction. We invite professional buyers and global dealers to witness the epitome of chastity and efficacity. For inquiries or to order your batch of the product, contact us at info@kintaibio.com. Our fast delivery and secure packaging ensure that you receive excellence in every package. Choose KINTAI for it – where quality meets innovation.
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