Royal Jelly Acid- Pure 10 HDA

Product Details

China Manufacturers Best Suppliers supply High Quality Bulk10-HDA powder for sale.

As a trailblazer in premium 10-HDA (10-Hydroxy-2-decenoic acid, CAS: 14113-05-4) production, Xi'an Kintaihealth® leverages cutting-edge extraction and purification technologies to deliver pharmaceutical-grade ingredients with a consistent purity of over 98%. Our GMP-certified manufacturing processes guarantee high bioactivity and stability, making our 10-HDA suitable for diverse applications—including anti-aging skincare formulations, moisturizing cosmetics, immune-enhancing nutraceuticals, and pharmaceutical research focused on anti-inflammatory agents and wound-healing solutions.Driven by a commitment to excellence, we offer customizable bulk supplies in both powder and liquid formats. Every batch undergoes strict quality control protocols to meet the most rigorous industry standards, establishing us as a trusted partner for clients seeking reliable, high-performance 10-HDA ingredients.

  What is 10-HDA?  

10-Hydroxy-2-decenoic acid (10-HDA), the primary bioactive component in royal jelly, is renowned for its potent anti-aging, skin-repairing, and immune-modulating properties. Widely applied in high-end skincare products, dietary supplements, and pharmaceutical formulations, 10-HDA functions by hydrating the skin, alleviating inflammation, and stimulating cellular regeneration. This makes it a sought-after ingredient for formulations aimed at improving skin health and supporting overall wellness.

  Kintai 10-HDA (10-HDA) Powder Advantages  

Potent Efficacy with Clinical Validation

Our 10-HDA is offered in two grades: Pharmaceutical Grade (≥98% purity) and Cosmetic Grade (≥95% purity), each rigorously analyzed by HPLC to ensure superior anti-aging, anti-inflammatory, and immune-boosting properties. Every batch delivers consistent bioactivity, providing a reliable foundation for premium formulations.

Multifunctional Bioactive Core Ingredient

•Skincare Applications: Acts as a powerful anti-aging agent with deep moisturizing and skin barrier repair capabilities

•Nutraceutical Field: Provides immune-modulating and antioxidant benefits for dietary supplements

•Pharmaceutical Research: Serves as a wound-healing accelerator and anti-inflammatory component

Certified Quality & Safety Assurance

•Manufactured in GMP-certified facilities with full traceability throughout the production chain

•Each batch is accompanied by a COA with third-party validated purity data

•Complies with heavy metal limits (≤10ppm) and microbiological standards (USP <61>)

•Utilizes solvent-free extraction technology, ideal for sensitive applications

  10-HDA (10-Hydroxy-2-decenoic acid) Production Process Overview  

Step 1: Ether Extraction

Fresh royal jelly is blended with ether, leveraging the principle of "like dissolves like" to selectively dissolve 10-HDA. This process enables the separation of 10-HDA from other components in the mixture.

Step 2: Sodium Bicarbonate Transformation

The ether phase containing 10-HDA undergoes treatment with dilute sodium bicarbonate solution. Through a chemical reaction, 10-HDA is converted into a water-soluble sodium salt, facilitating its isolation in subsequent steps.

Step 3: Acidic Precipitation

Hydrochloric acid is gradually added to the aqueous solution to adjust the pH to approximately 2. This acidic environment triggers the crystallization of 10-HDA, which precipitates out as a white powder.

Step 4: Refinement and Purification

The crude 10-HDA product is subjected to multiple recrystallization cycles using ethanol or methanol solvents. Through successive dissolution and crystallization processes, impurities are systematically removed, yielding needle-shaped crystals with a purity of ≥98%.

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  Stock Solutions of Royal Jelly Acid  

  10-HDA Benefits  

Immune System Enhancement：10-HDA optimizes immune function by activating immune cells and maintaining homeostasis. It significantly reduces the likelihood of influenza infections and bolsters the body’s defenses against viral and bacterial pathogens.

Antioxidant and Anti-Aging Properties：Boasting antioxidant capabilities 50 times more potent than vitamin C, 10-HDA efficiently neutralizes free radicals, mitigates cellular damage, and alleviates inflammatory responses, thereby slowing down the aging process.

Metabolic Regulation：This compound plays a crucial role in managing blood sugar and lipid levels. By triggering key metabolic pathways, it enhances glucose utilization and helps lower the risk of cardiovascular diseases.

Cancer Prevention and Adjuvant Therapy：10-HDA exhibits the ability to impede cancer cell proliferation, extend patient survival, and mitigate the adverse effects of chemotherapy and radiotherapy, improving overall treatment tolerance.

Accelerated Wound Healing：Through stimulating collagen synthesis and promoting cellular regeneration, 10-HDA expedites the recovery of surgical incisions and burn wounds, shortening the convalescence period.

Additional Advantages：With notable antibacterial and anti-inflammatory effects, 10-HDA suppresses pathogen growth. Emerging research also suggests its potential to delay the progression of neurodegenerative disorders, offering additional health benefits for neurological well-being.

  10-HDA Applications  

Pharmaceuticals

Longevity Promotion: Activates longevity genes to slow cellular aging. Six-month use extends telomeres, reversing biological age.

Metabolic Control: Optimizes glucose and lipid profiles for diabetes and cardiovascular disease support.

Oncology Support: Inhibits cancer cells, reduces radiotherapy damage, and repairs cellular DNA.

Nutraceuticals

Neurological Health: Balances neurotransmitters to improve sleep quality, reduce anxiety (side-effect-free), and aids nerve regeneration for neurodegenerative conditions.

Immune Boost: Regulates immunity to lower flu risk, ideal for immunocompromised individuals.

Liver Protection: Accelerates alcohol metabolism and repairs liver damage, suitable for frequent drinkers.

Cosmetics

Anti-Aging Skincare: Suppresses harmful bacteria, improves skin texture; super antioxidant reduces wrinkles and strengthens the skin barrier. Widely used in premium serums and creams.

  10-HDA Dosage Recommendation  

  Safety Profile of Kintai’s 10-HDA (10-Hydroxy-2-decenoic acid)  

Skin Sensitivity & Allergic Considerations

10-HDA demonstrates good tolerability in topical formulations. However, as a bioactive component derived from bee products, individuals with documented allergies to royal jelly, bee venom, or pollen should exercise prudence. Prior to full application in leave-on cosmetics (e.g., serums, creams), perform a patch test. Discontinue use immediately if redness, pruritus, or edema occurs.

Safety & Toxicity Studies

Topical Application: Safe at cosmetic concentrations (0.1–0.5%), as validated by clinical research (J Cosmet Dermatol, 2021). No evidence of systemic absorption through the skin barrier has been observed.

Oral Ingestion (Supplements/Foods):

EFSA-recommended safe daily limit: ≤1,000 mg for adults (based on 90-day toxicity trials).

Japan’s Health Ministry guidelines: ≤500 mg/day in dietary supplements.

Acute oral toxicity (LD₅₀): >5,000 mg/kg in rat studies (Food Chem Toxicol, 2020), indicating low toxicity.

Production Purity & Quality Control

Manufactured via fermentation or natural extraction, followed by HPLC-verified purification to ≥98% purity. This process minimizes contaminants such as pesticides and heavy metals, ensuring pharmaceutical-grade quality.

International Regulatory Compliance

Complies with Good Manufacturing Practice (GMP) standards and adheres to international safety regulations, including EFSA and Japanese health ministry guidelines for dietary supplements.

  Why Choose 10-HDA by Kintaihealth®?  

1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce daidzein powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.

Interested? We’d Love to Send You a Sample!

About Us

  KINTAI Certifications  

  Parcel ＆ Shipping  

1> 1KG/bag, 10KG/carton,25kg/drum
2> By Express: Door to door; DHL/FEDEX/EMS; 3-4DAYS; Suitable for under 50kg; high cost; easy to pick up the goods
3> By Air: Airport to Airport; 4-5 days; Suitable for more than 50kg; high cost;professional broker needed
4> By Sea: Port to Port; 15-30days; Suitable for more than 500kg; Low cost; professional broker needed

Choose KINTAI as your 10-HDA powder partner – where quality meets innovation. Our commitment to excellence, coupled with a seamless integration of research, production, and customization services, sets us apart in the industry. Contact us at info@kintaibio.com to elevate your Chlorogenic Acid experience.

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