Nicotinamide Riboside Hydrogen Malate NRHM Powder Supplier
Nicotinamide Riboside Hydrogen Malate (NRHM) is a stable complex salt formed by nicotinamide riboside and malic acid. As a derivative of vitamin B3, it serves as a prevalent oral NAD+ precursor ingredient. Compared with nicotinamide riboside chloride, it features lower hygroscopicity, superior heat and light resistance, better storage stability, and is less prone to moisture-induced degradation. It is widely applied in dietary supplements for energy support and daily wellness maintenance, as well as anti-aging skincare raw materials.
Healthkintai® specializes in the research, development and mass production of anti-aging active raw materials, with NAD+ precursors as our core flagship product line. Bulk Nicotinamide Riboside Malate NRHM powder is our star superior raw material, manufactured with a controlled purity range of 98% to 99%. New and existing clients are warmly welcome to contact us at health@kintaibio.com to request samples and discuss bulk order cooperation.


Nicotinamide Riboside Chloride Vs. Hydrogen Malate
|
Comparison Dimension |
NR-Cl |
NRHM |
|
Chemical Composition & CAS Number |
NR + Chloride ion; CAS: 23111-00-4 |
NR + Hydrogen malate ion; CAS: 2415659-01-5 |
|
Molecular Weight |
271.76 |
388.33 |
|
Storage Stability |
Poor; Strong hygroscopicity, the glycosidic bond is prone to breakage and degradation when exposed to light, moisture and high temperature; room temperature decomposition rate is about 8.37%, easy to discolor and agglomerate; requires light-proof refrigeration/inert gas preservation |
Excellent; Patented regular crystal form, low hygroscopicity; room temperature decomposition rate is only about 0.75%, resistant to light, heat and moisture; not easy to discolor and agglomerate, can be stored long-term at normal room temperature |
|
Synergistic Physiological Effects |
Simply supplies NR for conversion into NAD+ |
In addition to NAD+ generation, it provides malic acid, which participates in the mitochondrial tricarboxylic acid cycle, assists energy metabolism, and relieves post-exercise fatigue |
|
Core Advantages & Disadvantages |
Advantages: Sufficient clinical evidence, high effective NR content, affordable and widely available; Disadvantages: Poor stability, large storage loss, prone to gastrointestinal discomfort on an empty stomach |
Advantages: Excellent storage stability, mild to the gastrointestinal tract, wide application scenarios, synergistic mitochondrial energy support; Disadvantages: Insufficient clinical evidence, lower effective NR per equal weight, higher price |
What Are the Benefits of Nicotinamide Riboside Hydrogen Malate NRHM?
Nicotinamide Riboside Hydrogen Malate is a complex compound formulated from nr and hydrogen malate. Compared with conventional nicotinamide riboside products, it boasts superior physicochemical stability and gastrointestinal tolerance. Centered on two core functions-elevating bodily NAD+ levels and facilitating mitochondrial energy metabolism-it delivers a range of nutritional benefits for daily human health maintenance.
Better gastrointestinal compatibility and outstanding stability
Conventional NR-Cl available on the market contains chloride ions. For people with sensitive stomachs, prolonged consumption may lead to acid reflux and gastric discomfort. NRHM eliminates the irritating effects of chloride ions. Its mild weakly acidic property matches the gastrointestinal pH environment of the human body, delivering gentle effects without gastric irritation, making it safe for long-term intake even for those with sensitive digestion.
In addition, its complex salt structure drastically reduces the risks of moisture absorption and photodegradation. It retains its active potency for an extended period under room temperature and shaded storage conditions thanks to stable physicochemical properties, which makes it an ideal long-term daily dietary nutritional supplement.

Nicotinamide Riboside Hydrogen Malate Side Effects

NRHM boasts generally good tolerability, with most adverse reactions being mild, transient, and associated with dosage and fasting administration. Gastrointestinal discomfort including bloating, nausea, dull stomach pain and mild diarrhea commonly occurs at the initial stage of intake, which usually subsides naturally once the body adapts, or after taking the supplement with meals or reducing the dosage.
Long-term high-dose consumption continuously depletes the body's methyl donors, which may trigger a slight elevation in homocysteine levels and emotional irritability in susceptible individuals, a risk that can be effectively mitigated by concomitant supplementation with betaine, folic acid and vitamin B12. Allergic manifestations such as itchy skin and rashes are uncommon. To date, no conclusive evidence has proven that this ingredient causes organic liver or kidney damage. Nevertheless, pregnant women, lactating mothers, minors, individuals with a history of tumors, and chronic disease patients taking antihypertensive or hypoglycemic medications should exercise caution and consult a physician prior to use. Discontinue intake immediately and seek medical attention if persistent gastrointestinal distress, recurrent headaches or allergic reactions develop.
Where to Buy Nicotinamide Riboside Hydrogen Malate Powder?
Healthkintai® specializes in the supply of dietary supplement raw materials, boasting a comprehensive and extensive lineup of full-range NAD+ precursor ingredients for diverse selections. Our flagship product, Nicotinamide Riboside Malate NRHM powder, is synthesized through microbial fermentation technology. This eco-friendly and mild manufacturing process enables stringent impurity control. The entire production of all our products is conducted in strict accordance with GMP quality management specifications, backed by our in-house closed-loop quality inspection system.
We hold a complete set of qualifications for production, export, and testing. We are able to provide COA test certificates and batch traceability documents, catering to formula development and bulk raw material procurement demands of dietary supplement brands worldwide. Clients from home and abroad are welcome to contact us at health@kintaibio.com for business discussions, sample requests, and detailed specification documents.

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