Esculin Powder

Product Name: Esculin
CAS No.: 531-75-9
Molecular Formula: C15H16O9
Molecular Weight: 340.28
Appearance: White crystalline powderLead time: 1-3 days
Storage: Cool dry place and avoid light
Shelf Life: 2 years
MOQ: 1KG
Sample: Free sample available
Certifications: GMP, ISO9001:2016, ISO22000:2006, HACCP, KOSHER and HALAL
Advantage: 100,000 level clean production workshop, Non-additive, Non-GMO, radiationless qualified product.
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service

Product Introduction

As a supplier of Esculin Powder, Healthkintai® offers Esculin Powder with a 98% purity level verified by HPLC, setting it apart from the average specifications available in the market. What distinguishes us further is our comprehensive certification portfolio, which includes GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL. These certifications underscore our commitment to adhering to stringent international standards, ensuring that our Esculin Powder not only meets but exceeds the rigorous quality, safety, and regulatory requirements across global markets. Whether for pharmaceutical, cosmetic, or other industrial applications, Healthkintai® stands as a reliable partner providing high-purity, fully certified Esculin Powder you can trust.

 What Is Esculin Powder 

Esculin powder is a kind of white crystalline powder extracted from the dry branch bark or trunk bark of Fraxinus rhynchophylla and other plants of the Oleaceae family, which is the active ingredient of the traditional Chinese medicine Qinpi. Its chemical name is 6-(β-D-glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one, and its molecular formula is C₁₅H₁₆O₉.Aesculin powder has a slightly bitter taste. It is soluble in hot alcohol, methanol, pyridine, ethyl acetate, and acetic acid, and can also be dissolved in water. It has a melting point of 205°C (decomposed) and an optical rotation of -79° (c=2.4, 50% dioxane).This powder has a variety of biological activities. It has anti-inflammatory, antibacterial, anticoagulant, and analgesic effects, and can significantly increase the urine output of mice. In addition, it can inhibit the aldose reductase of rat eye lenses, is a growth inhibitor of Bacillus subtilis, and also has an inhibitory effect on chemical carcinogenesis. In the field of microbiology, Aesculin powder can also be used for the isolation and identification of Enterococcus (group D streptococci).

Esculin Powder

 Physical And Chemical Properties 

Molecular Formula:

C15H16O9

Molecular Weight: 340.28
CAS No.: 531-75-9
Storage
(From the date of receipt):
3 years -20°C powder
  1 year -80°C in solvent
Image: product-250-1

 Kintai Esculin Powder Advantages 

 

Unrivaled Purity

Kintai Aesculin Powder stands out with an exceptional purity level of 98% as verified by HPLC, far exceeding average market standards. This high purity ensures minimal impurities, guaranteeing consistent bioactivity and reliability in applications ranging from pharmaceuticals to cosmetics, where precision and efficacy are paramount.

Industry Leadership

As a front-runner in the field, Kintai sets benchmarks through its advanced extraction and purification technologies. Our commitment to innovation ensures that our Aesculin Powder not only meets but anticipates industry demands, delivering a product that supports cutting-edge research and high-performance formulations across global markets.

Stringent Safety & Compliance

Kintai Esculin Powder adheres to the strictest international standards, backed by certifications including GMP, ISO9001:2015, ISO22000:2018, HACCP, KOSHER, and HALAL. These credentials validate rigorous quality control throughout the production chain, ensuring safety, traceability, and compliance with regulatory requirements worldwide.

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 Esculin Powder Manufacture Processing 

 

 

Esculin Powder manufacture processing

Method​

Advantages​

Disadvantages​

Applicable Scenarios​

Hot Reflux​

Mature operation​

High energy consumption, emulsification risk​

Small-scale production​

Microwave Extraction​

Efficient, energy-saving, high yield​

Higher equipment cost​

Industrial rapid extraction​

Notes:​

Esculin in aqueous solutions with pH > 5.8 exhibits blue fluorescence, which can be used for preliminary qualitative detection.​

Avoid prolonged high-temperature treatment to prevent Aesculin decomposition (melting point 204-206°C) .​

The above processes can be selected (traditional or microwave-assisted extraction) based on Healthkintai®’s actual production needs (e.g., scale, cost control), with further parameter optimization. For specific parameter validation experiments, refer to microwave extraction research data or purification cases .

 Esculin Powder Specifications 

 

Product name

Esculin powder

Extract source

The bark of the ash tree of the Oleaceae family.

Extraction Solvent

ethanol

Appearance

White powder

Solubility

Soluble in hot alcohol, methanol, pyridine, ethyl acetate, and acetic acid (hydrate).

Identification

HPLC

Ash

NMT 0.5%

Heavy metals

NMT 20 PPM

Loss On Drying

NMT 5.0%

Powder size

80Mesh, NLT90%

Assay

Min. 95.0%

Residual Solvents

 

- Ethanol

NMT 5000 PPM

Microbiological Quality (Total viable aerobic count)

 

- Bacteria, CFU/g, not more than

NMT 103

- Moulds and yeasts, CFU/g, not more than

NMT 102

- E.coli, Salmonella, S. aureus, CFU/g

Absence

Storage

In a Tight, Light-resistant, and Dry Place. Avoid Direct Sunshine. Country of Origin: China

Shelf life

3 years

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 Esculin Powder Benefits 

Potent Antimicrobial Effects

Aesculin Powder demonstrates strong inhibitory activity against a broad spectrum of microorganisms, including common pathogens like Staphylococcus aureus, Escherichia coli, and certain fungi. This antimicrobial prowess stems from its ability to disrupt microbial cell structures and interfere with their metabolic processes, making it a valuable component in pharmaceutical formulations for treating minor skin infections, wound care products, or even oral hygiene solutions. In research settings, it also serves as a tool to study microbial resistance and develop targeted antimicrobial strategies, highlighting its versatility beyond direct therapeutic use.

Anti-Inflammatory Properties

 By modulating key inflammatory mediators and pathways—such as reducing the release of pro-inflammatory cytokines—Esculin Powder effectively alleviates inflammatory responses. This makes it particularly beneficial in soothing skin conditions like acne, eczema, or sunburn, where redness and irritation are prominent. Additionally, its anti-inflammatory action extends to supporting joint and mucosal health, potentially aiding in managing mild inflammatory discomfort in these areas. Its natural origin also adds appeal for formulations seeking plant-derived alternatives to synthetic anti-inflammatory agents.

Antioxidant Benefits

As a robust antioxidant, Asculin Powder scavenges harmful free radicals that contribute to cellular damage and aging. By neutralizing these reactive molecules, it helps protect skin cells from oxidative stress, slowing down signs of premature aging like fine lines and dullness—this explains its common inclusion in anti-aging skincare serums and creams. Beyond cosmetics, its antioxidant activity supports overall cellular health, with studies suggesting potential roles in protecting vascular endothelial cells and reducing oxidative damage in various tissues, further expanding its applications in wellness and preventive health.

Ophthalmic Support

Esculin Powder has a long history of use in supporting ocular health, thanks to its dual action of reducing inflammation and soothing irritated tissues. It is often incorporated into ophthalmic formulations, such as eye drops or gels, to relieve symptoms of mild eye conditions like conjunctivitis, keratitis, or dry eye syndrome. Its ability to calm inflamed ocular surfaces and promote gentle healing makes it a trusted ingredient in eye care products, providing targeted relief while minimizing irritation—an important consideration for sensitive eye tissues.

Anti-Inflammatory

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 Esculin Powder Applications 

Pharmaceutical Formulations

 Esculin Powder is widely integrated into pharmaceutical products, particularly those targeting microbial infections and inflammatory conditions. It can be found in oral medications for treating mild bacterial infections, topical ointments for skin inflammations or wound healing, and ophthalmic preparations (such as eye drops or gels) to alleviate symptoms of conjunctivitis and keratitis, leveraging its antimicrobial, anti-inflammatory, and soothing properties.

Cosmetics and Skincare Products

Due to its antioxidant and anti-inflammatory characteristics, it is a key ingredient in various skincare formulations. It is often added to anti-aging serums, moisturizers, and acne treatments to neutralize free radicals, reduce redness, soothe sensitive skin, and support the repair of damaged skin barriers, making it suitable for both daily care and targeted solutions for problematic skin.

Research and Laboratory Reagents

 In scientific research, Aesculin Powder serves as a valuable tool in microbiology and biochemistry studies. It is used in microbial identification tests (e.g., differentiating certain bacterial strains based on their ability to hydrolyze esculin) and in exploring the mechanisms of antioxidant and anti-inflammatory compounds, providing insights for developing new therapeutic agents.

Nutraceutical and Wellness Products

 Given its potential benefits for vascular health and cellular protection, Aesculin Powder is incorporated into some nutraceutical supplements. These products are designed to support circulatory wellness, combat oxidative stress, and promote overall cellular health, catering to consumers seeking natural ingredients for preventive health maintenance.​​​​​​​

Cosmetics Esculin

Cosmetics Esculin

Pharmaceutical Esculin

Pharmaceutical Esculin

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 Why Choose Esculin Powder By Healthkintai®? 

1. We promise that our raw materials are naturally grown without any additives.
2. We provide customized extraction solutions to produce Aesculin Powder in various specifications tailored to your requirements.
3. Our production facilities hold internationally recognized certifications including GMP, ISO 9001, ISO 22000, HACCP, KOSHER, and HALAL, guaranteeing the highest standards for your peace of mind.


KINTAI is a leading manufacturer and supplier of Esculin Powder. With our state-of-the-art research and development center, production facilities, multiple patents, and quality certifications, we ensure the highest standards of product quality. We support customized products and provide integrated service solutions. Our fast delivery and secure packaging guarantee a great customer experience. We provide free samples for testing, if you want to purchase high quality Aesculin Powder, please feel free to contact us at info@kintaibio.com.

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