Burdock Seed Extract Arctiin

Burdock Seed Extract Arctiin Manufacturers and Suppliers​​​​​​​

Arctiin is the core lignan active ingredient in the dried, mature seeds (burdock seeds) of the Asteraceae plant. As the main active ingredient in burdock seed extract, it possesses multiple biological activities, including anti-inflammatory, antioxidant, antibacterial, and antiviral properties. Modern pharmacological research focuses on its potential effects in anti-tumor activity, neuroprotection, improvement of insulin resistance, and promotion of bone health.

Healthkintai^® is a leading manufacturer and supplier of Arctiin Powder in China. We offer 20%30% Burdock Seed Extract Arctiin from natural sources (other specifications can be customized). Please feel free to contact us at info@kintaibio.com.

KINTAI Arctiin Specifications

Physicochemical Properties of Arctiin

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Arctiin Mechanism of Action

Arctium Extract Arctiin is a lignan glycoside derived from traditional Chinese medicines such as burdock seed. Its core mechanism of action involves conversion by gut microbiota into the active metabolite arctigenin, which exerts its pharmacological effects. Arctigenin primarily exhibits significant anti-inflammatory and immunomodulatory activities, reducing the production of pro-inflammatory cytokines (such as TNF-α and IL-6) by inhibiting key signaling pathways (such as NF-κB). Furthermore, studies have shown that it possesses antioxidant, antiviral (e.g., influenza virus) and potential antitumor effects, inhibiting the proliferation of certain cancer cells by influencing the cell cycle and inducing apoptosis. Therefore, arctiin is considered a prodrug with multi-target therapeutic potential.

Burdock Seed Extract Benefits

Anti-inflammatory and Immunomodulatory Effects

Arctiin strongly inhibits the production of key pro-inflammatory factors (such as TNF-α and IL-6) and blocks excessive inflammatory responses at their source by precisely regulating core inflammatory signaling pathways such as NF-κB and MAPK. This effect not only forms the pharmacological basis for its relief of arthritis, allergic dermatitis, and lung inflammation but also provides its core value in improving metabolic diseases driven by chronic inflammation (such as diabetes and atherosclerosis).

Anti-tumor Potential

Arctiin and its metabolite arctiin can inhibit cancer cells through multiple pathways. Its mechanisms include inducing tumor cell apoptosis, arresting the cell cycle in the G1 phase, inhibiting cancer cell invasion and metastasis, and counteracting tumor angiogenesis. Studies have confirmed its significant growth-inhibiting effects on various cancer cell lines, including breast cancer, lung cancer, prostate cancer, and colorectal cancer, demonstrating its great potential as a natural anti-cancer lead compound.

Neuroprotective and Cognitive Improvement Abilities

Arctium Extract Arctiin can effectively penetrate the blood-brain barrier, reducing oxidative stress and neuroinflammation in the brain through its powerful antioxidant and anti-inflammatory properties. It is particularly effective in counteracting the neurotoxicity of β-amyloid protein, protecting neuronal function, and improving learning and memory impairments in experimental animals. These properties have made it a focus of attention in the prevention and treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's.

Arctium Extract Arctiin Benefits for Men

Burdock extract (especially derived from burdock seeds) offers multiple benefits for men's health. Its main active ingredients, arctiin and arctidin, can regulate hormone balance and inhibit the excessive conversion of testosterone to dihydrotestosterone, thereby supporting prostate health and reducing the risk of hyperplasia. Its potent anti-inflammatory and antioxidant properties help alleviate chronic prostate inflammation and systemic oxidative stress, potentially indirectly improving sperm quality. Simultaneously, this extract can enhance liver detoxification and promote the metabolism of toxins in the body, supporting overall vitality and metabolic health. It is recommended as a natural supplement for men's health, but professional advice should be sought before use.

Arctiin for Skin

Arctiin, a key compound in burdock seed, offers multiple skin benefits. Its potent anti-inflammatory action soothes irritation and redness, making it effective against acne and eczema. As a strong antioxidant, it protects skin from environmental damage and may slow aging signs. Research also indicates it can boost collagen production, enhancing skin elasticity and firmness. Additionally, it supports detoxification, helping to clarify complexion.

Arctiin Uses

Arctiin Pharmaceuticals and Supplements

This is the most promising core application area for Arctium Extract Arctiin. Based on its well-defined pharmacological activities, including anti-inflammatory, anti-tumor, neuroprotective, and metabolic-regulating effects, arctiin is being extensively researched and developed into various novel drugs and functional health products. Specific directions include: development as a lead compound for anti-inflammatory and analgesic drugs; treatment drugs for neurodegenerative diseases such as Alzheimer's; chemotherapy sensitizers or targeted agents to aid in anti-tumor therapy; and natural health ingredients for regulating blood sugar and lipids and improving insulin resistance. Its origin as a traditional medicinal and edible plant adds to its safety profile.

Functional Foods and Beverages

With the popularization of the concept of "medicine and food from the same source," arctiin, as the signature active ingredient in burdock, is widely used in various functional foods. For example, it is added to special dietary foods to help manage diabetes and obesity; used in health drinks to combat fatigue and enhance immunity; or added as an antioxidant to health foods to help consumers resist oxidative stress and chronic inflammation. This gives ordinary foods a clear added health value.

​​​​​​​Arctiin for Skincare and Cosmetics

With its outstanding anti-inflammatory, antioxidant, and collagen-synthesizing bioactivity, Burdock Seed Extract Arctiin has become a rising star among skincare ingredients. It is used in soothing and repairing products for sensitive and acne-prone skin, effectively reducing redness and irritation. Its antioxidant capacity helps anti-aging products resist photodamage and free radicals, delaying wrinkle formation. Simultaneously, its properties of promoting skin microcirculation and metabolism are also used in skincare products that improve skin tone and create a healthy glow.

Side Effects of Burdock Seed Extract Arctiin

Arctiin, as a natural active ingredient, is generally considered safe when used at prescribed doses and under normal conditions, but it is not entirely without the risk of side effects. The main risk stems from gastrointestinal irritation; some individuals may experience nausea, bloating, abdominal pain, or diarrhea after overdose. Because arctiin has potential hypoglycemic and anticoagulant (blood-activating) effects, individuals with hypoglycemia or those taking hypoglycemic drugs or anticoagulants (such as warfarin) should exercise extreme caution, as it may lead to excessively low blood sugar or increase the risk of bleeding.

Furthermore, a very small number of individuals with allergies may experience allergic reactions such as rashes and itching. Although its toxicity is low, safety data for long-term, high-dose use are still insufficient. Therefore, it is recommended that before using any supplements or medications containing arctiin, especially pregnant women, breastfeeding women, and patients with chronic diseases, consult a professional physician or pharmacist to ensure medication safety.

Why Choose KINTAI Arctiin?

• Premium Raw Materials: We rigorously select high-quality burdock seeds from pollution-free production areas. Through scientific cultivation and traceability management, we ensure high and stable arctiin content in the raw materials, guaranteeing product purity and efficacy from the source.
• Multiple Specifications & Customization: We offer multiple specifications of arctiin. Our product specifications can be customized to precisely match the R&D and production needs of clients in different industries such as pharmaceuticals, health products, and cosmetics.
• Authoritative International Certifications: Our products have fully passed international quality management and certification standards such as ISO, HACCP, Halal, and Kosher, and come with detailed COA (Certificate of Account) reports, ensuring safety and reliability, and meeting global market access standards and high-end quality requirements.

FAQ

Q1:What are the benefits of Arctigenin?

A1:Arctigenin, the active metabolite of Arctiin, offers multiple health benefits. Primarily, it exhibits potent anti-inflammatory effects by inhibiting NF-κB signaling. It also shows antiviral activity against viruses like influenza. Promising research highlights its anti-cancer potential, as it can inhibit proliferation and induce apoptosis in various cancer cells. Additionally, it provides antioxidant and neuroprotective benefits, making it a compound of significant therapeutic interest.

Q2:Does burdock root heal the liver?

A2:Burdock root is traditionally used in herbal medicine to support liver health. Modern studies indicate it contains antioxidants like arctigenin, which may help protect liver cells from damage and reduce inflammation. While some research in animals and cells shows potential benefits for toxin-induced liver injury, strong clinical evidence in humans is still lacking. Therefore, it is best considered a supportive complementary ingredient, not a proven treatment for liver diseases.

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