Flaxseed Extract Flax Lignan Secoisolariciresinol Diglucoside (SDG) Powder

Flaxseed extract contains secoisolariciresinol diglucoside (SDG, also known as flax lignan) as its core active ingredient, which is extracted from the seed coat of dried-ripe Linum usitatissimum (Linaceae). It delivers antioxidant effects, phyto-estrogen modulation, anti-inflammatory benefits, auxiliary regulation of blood lipids and blood glucose, cardiovascular protection, and relief of menopausal symptoms. Widely adopted in dietary supplements, functional foods, skincare formulations, oral nutraceuticals, pet nutrition products and feed additives, this natural botanical raw material is commonly formulated for menopausal support, metabolic regulation and anti-aging skincare products.

With more than 10-year expertise in plant-extract R&D and manufacturing, Healthkintai^® supplies flaxseed extract flax lignans secoisolariciresinol diglucoside sdg powder with multiple standard grades. Custom-tuned formulas are available to match your production needs. Contact us at health@kintaibio.com to start your partnership.

Generally speaking, there is no unified regulatory standard for flaxseed lignans worldwide. Its regulatory classification strictly depends on the specific use and the target market, but the vast majority of countries classify it as a dietary supplement or functional food ingredient, rather than as a pharmaceutical drug.

The USA FAD

The US FDA classifies standardized secoisolariciresinol diglucoside (SDG‑rich flaxseed extract) as a dietary‑supplement ingredient, which does not require pre‑market FDA approval. Low‑purity crude flaxseed extract with low SDG content has obtained GRAS status and can be applied in fortified foods, granola bars, functional beverages and dietary supplements. High‑purity standardized flaxseed extracts (20%‑80% SDG) fall under dietary‑supplement ingredients without prior FDA clearance. Permitted structure‑function claims include hormone‑balance modulation, antioxidant support, menopausal‑discomfort relief and cardiovascular‑health maintenance. This ingredient can also be formulated into cosmetics. High‑purity SDG is not approved as an active pharmaceutical ingredient and may be freely used in cosmetic applications.

EU EFSA

The EU maintains the strictest regulatory framework. Flaxseed extracts with an SDG content above 5% are classified as Novel‑Food, which requires an EFSA food‑safety assessment plus authorization from the European Commission for circulation across the entire EU. Only the EU‑approved basic antioxidant‑related health claims are permitted; claims regarding hormone regulation and menopausal‑condition management are prohibited. SDG is listed in the CosIng cosmetic‑ingredient inventory, approved as an antioxidant and skin‑soothing agent for skincare and hair‑care formulations without banned‑usage restrictions. SDG can also be adopted as a botanical feed additive subject to registration under EU feed‑additive regulations.

What Are Flax Lignans and Flaxseed?

Flaxseed: The whole-form seed of flax plant, a natural whole-grain raw material with complex constituents. It comprises oil (alpha-linolenic acid, Omega-3), dietary fiber, protein, flax lignan, carbohydrates and phytic acid. Secoisolariciresinol diglucoside (SDG, flax lignan) is exclusively concentrated within the flaxseed hull.

Flax Lignan: A core active lignan-type substance purified from flaxseed seed coat. It acts as the principal functional component of flaxseed for endocrine modulation, antioxidant activity, prostate protection and menopause relief, classified as a standardized raw material.

Botanical Source of Flax Lignans

Plants such as sesame, barley, and carrots also contain lignans, but their levels are significantly lower than those in flaxseed. We choose flaxseeds produced in Huining, Gansu as our botanical source. Huining is acclaimed as the "Flaxseed Capital of China," all thanks to its climatic features-consistently low rainfall, abundant sunlight, and significant diurnal temperature variation-coupled with its pollution-free environment and soil rich in elements such as magnesium, manganese, vanadium, selenium, and molybdenum. Our flaxseed lignans SDG is primarily extracted from the dried seeds of flax (Linum usitatissimum) , specifically from the flaxseed hulls, as they contain the highest concentration of the lignan.

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Flaxseed Extract Flax Lignans for Estrogen

Secoisolariciresinol diglucoside (SDG) is a type of phytoestrogen. After oral intake, it is metabolized into enterodiol and enterolactone by gut‑microbiota. Its core mechanism lies in the bidirectional regulation of estrogen levels.

• In cases of reduced endogenous estrogen secretion (during menopause or natural ovarian function decline), metabolites of secoisolariciresinol diglucoside bind to estrogen receptors and exert mild estrogen‑like activity. They offset hormone deficits caused by insufficient endogenous estrogen and relieve physical discomforts triggered by hormonal imbalance.
• When excess estrogen accumulates in the body (such as in cases of mammary hyperplasia, uterine fibroids and ovarian cysts), SDG metabolites competitively occupy estrogen‑receptor binding sites, mitigating excessive stimulation of target tissues including the breasts, uterus and ovaries by native human estrogen. Meanwhile, they inhibit aromatase activity, block the conversion of testosterone into estradiol, curtail surplus estrogen synthesis at the metabolic source, stabilize overall estrogen concentrations and preserve endocrine homeostasis.

Flaxseed Extract Flax Lignans for Hair

Lignans from flaxseed extract can combat androgenetic alopecia by regulating hormonal balance. They inhibit the activity of 5α-reductase, reducing the conversion of testosterone into the more potent dihydrotestosterone (DHT), thereby protecting hair follicles from DHT-induced damage. At the same time, lignans modulate the levels of sex hormone-binding globulin (SHBG), further balancing free sex hormones. In addition, they possess anti-inflammatory and antioxidant properties, which help alleviate scalp inflammation and reduce oxidative damage to hair follicles. By also improving scalp microcirculation, they collectively create a favorable environment for hair growth, thereby promoting hair regrowth and reducing hair loss.

Flaxseed Extract Flax Lignans for Dogs

Flax hull lignans deliver multiple-faceted health benefits for dogs. Primarily, it acts as a potent antioxidant to combat free-radical damage throughout the body. Moreover, its anti-inflammatory properties help ease discomfort triggered by conditions such as arthritis and support cardiovascular wellness. It further promotes healthy skin and a lustrous coat, while exerting a positive effect on hormone regulation, including auxiliary management of Cushing's disease.

Flax Lignans Dietary Supplements

Standardized flaxseed lignan extracts are mainly processed into soft capsules, tablets and composite powdered nutritional supplements, with formulas developed specifically for three major consumer groups: women with endocrine imbalances, men with prostate concerns, and middle-aged and elderly people with cardiovascular issues. Formulas blended with lycopene and saw palmetto are produced as prostate-support supplements for men; meanwhile, combinations of Omega-3, white kidney bean extract and Coenzyme Q10 are formulated into metabolism-support product lines.

Flax Lignans Cosmetics

SDG flaxseed lignan has become a popular natural botanical ingredient for anti-aging, skin repair and anti-hair loss hair care products, covering two major segmented product lines: facial skincare and scalp care. It is incorporated into anti-aging serums, spot-fading lotions and barrier-repair creams for facial skincare; and added to anti-hair loss shampoos and scalp essences for scalp care products. In addition, it is used in body lotions, anti-wrinkle neck creams and eye repair products. We can also supply standardized water-soluble flaxseed lignan specifications specially formulated for cosmetic applications.

Flax Lignans Supplements for Pets

Flaxseed lignan is commonly added to canine nutritional supplements and functional dog food. It alleviates skin itching, excessive hair loss and overactive sebum secretion triggered by hormonal disorders, regulates lipid metabolism, and relieves prostate discomfort and urinary tract aging issues in senior male dogs. Free of synthetic hormone residues, this ingredient can also be blended with fish oil, cranberry extract and lecithin to nourish the coat and boost the body's antioxidant capacity.

Secoisolariciresinol diglucoside (SDG) is a natural plant active ingredient so it can be safe when used within the recommended dosage. Its side effects are usually mild.

Gastrointestinal discomfort:

Bloating, diarrhea, abdominal pain, and increased flatulence.

(A small number of people may experience nausea or constipation.)

Recommendations for management:

You can start with 50mg per day and gradually increase to the recommended dosage to avoid large intakes at one time, take with meals to reduce gastrointestinal irritation and drink plenty of water to aid the metabolism of dietary fiber and alleviate discomfort.

Healthkintai^® is a professional manufacturer and supplier of raw materials for dietary supplements. Our advantages are as following:

• Whole-process low-temperature treatment maximizes the retention of SDG's pubchem.
• Adopting the combined process of "ethanol extraction + resin purification," the product purity reaches over 40%.
• Process wastewater and waste residues are recyclable, meeting green production requirements and suitable for the large-scale supply of raw materials for functional foods and health supplements.

If you are looking for bulk flaxseed extract flax lignan secoisolariciresinol diglucoside (sdg) powder, please contact us at health@kintaibio.com.

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