Black Cumin Nigella Sativa Extract Powder

Nigella sativa extract, also called black cumin seed extract, is derived from the dried ripe seeds of plants belonging to the genus Nigella (Ranunculaceae), such as Nigella sativa and Nigella damascena. Its core active constituent is represented by thymoquinone (TQ), supplemented by nigellicine, nigellone, quercetin, etc. Thymoquinone possesses key effects, including anti-inflammation, antioxidant, antibacterial, and immunoregulation activities; it can assist in liver protection, regulate blood glucose and lipids, relieve respiratory discomfort, and also shows application value in hair growth, hair care, and skin barrier repair. It is widely used in four major fields: medicine, health care products, cosmetics, and the food industry.

Healthkintai^® is a leading manufacturer and supplier of plant extracts in China with over ten years of industry experience. We offer a complete range of Black Cumin Nigella Sativa Extract Powder specifications, including 5%, 10% and 20% Thymoquinone, featuring stable purity, natural ingredients, and no additives. Welcome to contact us at health@kintaibio.com for inquiries and quotations at any time.

Whole seeds and crude processed products of Nigella sativa are recognized as natural raw materials with traditional edible history in most regions worldwide. Their specific regulatory status is as follows:

In the United States: Nigella sativa seeds and their crude products are designated as Generally Recognized as Safe (GRAS) by the FDA and can be legally produced and marketed as food flavorings and dietary supplement ingredients.

In countries such as Canada and Australia: Such raw materials are regulated under the natural health product system and can only be legally distributed as health products after completing official registration, approval, and obtaining corresponding certification numbers.

Healthkintai's Nigella sativa seed extract is produced using Nigella sativa seeds as raw material.

• First, ethyl alcohol is added for extraction.
• After the extract undergoes refined filtration, the solvent is recovered for recycling.
• Purified water and diatomaceous earth are then added for purification treatment, followed by concentration and deployment processes in sequence to obtain a standardized concentrated solution.
• The subsequent steps include spray drying, packaging, and storage.

The entire process must be operated in a Class 300,000 clean zone, ultimately yielding Nigella sativa seed extract finished products that meet all required standards. Our extraction flow chart is as follows:

Antioxidant Activity of Nigella Sativa Extract

The core active component of nigella sativa extract, thymoquinone, exhibits significant antioxidant activity through two main mechanisms: direct free radical scavenging and indirect enhancement of the body's antioxidant system.

 

On the one hand, it can directly neutralize excess reactive oxygen species in the body, inhibit lipid peroxidation, and reduce oxidative damage to cell membranes, mitochondria and DNA caused by oxidative stress. On the other hand, it can up-regulate the expression and activity of the body's endogenous antioxidant enzymes, strengthening the inherent antioxidant defense capacity of cells.

Anti-inflammatory Effect of Nigella Sativa Extract

The anti-inflammatory effect of nigella sativa extract is mainly mediated by its core component, thymoquinone, which can inhibit inflammatory signaling pathways and the release of pro-inflammatory factors.

 

Thymoquinone significantly suppresses the activation of the NF-κB inflammatory signaling pathway, reduces the production and release of major pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6, and decreases the generation of inflammatory mediators including prostaglandins and nitric oxide.

 

It thereby alleviates local redness, swelling, heat, pain and chronic inflammatory responses, while inhibiting inflammatory cell infiltration and tissue damage, achieving a mild and stable anti-inflammatory effect.

Nigella Sativa Extract thymoquinone for hair

Thymoquinone can improve local microcirculation of the scalp and promote unobstructed blood circulation, thereby providing sufficient nutrient supply to hair follicles. Meanwhile, it exerts a significant anti-inflammatory effect, inhibits chronic scalp inflammation, reduces dandruff and scalp redness, and creates a healthy growth environment for hair follicles.

 

In addition, the antioxidant property of thymoquinone eliminates free radicals around the scalp and hair follicles, reduces oxidative stress damage to hair follicle cells, delays premature follicle aging, prolongs the anagen (growth) phase of hair, thus reducing hair loss and improving hair thinning.

 

Furthermore, it nourishes the scalp stratum corneum, enhances hair toughness, relieves dryness, frizz and breakage, helps repair damage caused by hair dyeing and perming, and makes hair smoother and shinier.

Nigella Sativa Extract Thymoquinone for Man and Woman

The core benefits of thymoquinone for both men and women stem from its potent antioxidant, anti-inflammatory properties as well as its ability to regulate hormones and metabolism.

 

For men, it alleviates oxidative stress and inflammatory damage in the reproductive system, protects sperm quality and motility, and maintains prostate health by modulating androgen receptors and metabolic balance.

 

For women, it regulates estrogen metabolism, relieves inflammatory discomfort associated with premenstrual and menopausal syndromes, improves the hair follicle microenvironment to reduce hair loss and hyperpigmentation, and optimizes glucose and lipid metabolism via the AMPK pathway to assist with weight and blood glucose management.

Thymoquinone Supplement

Black cumin seed extract is commonly available in the form of standardized extract capsules, tablets and compound nutritional formulas. It mainly exerts potent antioxidant, anti-inflammatory and metabolic regulatory effects, helping the body scavenge free radicals, alleviate chronic inflammation, regulate blood glucose and lipid levels, and enhance immune function. Meanwhile, it supports male prostate health and female endocrine regulation, and also assists in liver protection and stress relief.

Thymoquinone Cosmetics

Black seed extract containing thymoquinone is often incorporated into serums, creams, facial masks, and scalp care products. It can effectively scavenge free radicals; defend against environmental damage; soothe sensitive, red, and inflamed skin; and inhibit melanin deposition and even out skin tone, as well as repair the skin barrier and slow down skin aging. When used in hair care products, it nourishes the scalp, improves the follicular microenvironment, reduces hair loss, and strengthens hair strands.

Thymoquinone in food

Nigella sativa extract can be used in foods as a natural spice to impart a distinctive flavor. Thanks to the antioxidant and antibacterial properties of thymoquinone, it also serves as a natural preservative and antioxidant for oils, meat products, baked goods and others, effectively delaying lipid oxidation and rancidity, inhibiting microbial growth, and extending shelf life. Meanwhile, it can be applied as a functional food additive in health drinks, meal replacements, sauces and other products to provide certain antioxidant and anti-inflammatory nutritional benefits.

For adults, a daily intake of 20 mg of thymoquinone is recommended for general health maintenance. For short-term anti-inflammatory and conditioning purposes, the dosage may be increased to 30–50 mg per day, with a safe upper limit of 50 mg daily. Excessive intake may cause gastrointestinal discomforts such as nausea, bloating, and diarrhea. Pregnant or breastfeeding women, children, and individuals with impaired liver or kidney function are not advised to take supplements on their own. Those taking medications such as hypoglycemics, antihypertensives, or anticoagulants should consult a doctor first. It is recommended to take it with meals and start with a low dose, adjusting gradually.

Healthkintai^® is a professional Chinese manufacturer and supplier of high-quality plant extracts. Nigella sativa extract powder stands as one of our core products. Please feel free to contact us at health@kintaibio.com.

• We are able to provide non-GMO certification;
• Our production processes strictly comply with GMP standards;
• Our products meet regulatory requirements for heavy metals and microbial limits.
• Custom OEM and ODM services are also available.

Reference:

https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/

https://pubchem.ncbi.nlm.nih.gov/compound/Thymoquinone

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