Naringin Powder

Naringin powder occurs naturally in plants of the Brassicaceae family, it demonstrates notable anti-inflammatory properties, lowers blood viscosity, minimizes thrombus formation, and exhibits analgesic, sedative effects, as well as augmenting bile secretion.Healthkintai^® is a premier supplier of Naringin Powder, offering a premium-grade ingredient with a guaranteed 98% purity-a testament to our commitment to superior quality. This high purity ensures a consistently potent and reliable material that integrates effortlessly into your formulations for dietary supplements, functional beverages, and cosmetics, enabling you to fully harness the benefits of naringin.Contact us at info@kintaibio.com.

Raw Material Pretreatment and Extraction: After drying and crushing the grapefruit peel, it is extracted using solvents such as water and ethanol at a specific temperature to dissolve and separate the target active ingredient from the raw material.

Purification and Concentration: The extract is selectively adsorbed, eluted, and filtered using macroporous adsorption resins and membrane separation techniques to remove impurities and initially enrich the active ingredients. The extract is then evaporated and concentrated.

Drying and Forming: The concentrated refined liquid is spray-dried or vacuum-freeze-dried to produce a powdered product with stable composition, easy to store, and easy to use.

Naringin is a natural flavonoid compound found in the peel and pulp of grapefruit, tangerine, and orange, all members of the Rutaceae family. Studies have shown that naringin can effectively improve hepatic lipid metabolism in hyperlipidemic mice. It significantly promotes AMPK expression in the liver tissue of hyperlipidemic mice and inhibits the expression of HMGCR and SREBP.

The relationship between naringin and grapefruit seed extract (GSE) is that of a single constituent to a complex mixture; the former is a naturally occurring component of the latter, which is an extract system comprising a multitude of substances. As a glycoside formed by naringenin linked to a disaccharide moiety, naringin is an identified flavonoid component in GSE, present at a concentration of approximately 3.82 μg/mL. However, the chemical composition of GSE is far more complex; GC-MS analysis reveals the presence of various fatty acids, terpenes, alcohols, and phenolic compounds. Furthermore, pure, natural grapefruit seed extract exhibits only weak antimicrobial activity on its own; the broad-spectrum antimicrobial efficacy observed in commercial products is often primarily attributable to synthetic preservatives added during processing-such as benzalkonium chloride or triclosan-rather than to natural constituents like naringin.

naringin for blood pressure

Naringin exhibits a clear antihypertensive effect. In animal models of hypertension, naringin effectively prevents blood pressure elevation; this mechanism is closely linked to the inhibition of the renin-angiotensin system (RAS), specifically through the downregulation of signaling pathways involving angiotensin II type 1 receptor (AT1R), protein kinase C, and NADPH oxidase 2, as well as the alleviation of oxidative stress and inflammatory responses, thereby ameliorating left ventricular-aortic dysfunction and remodeling. Furthermore, naringin exerts indirect cardioprotective effects by activating AMPK and improving endothelial function. Preclinical studies indicate that naringin holds great promise for hypertension management and is regarded as a potential alternative therapeutic option.

naringin for bodybuilding

Naringin exerts multi-pathway regulatory effects on body composition, primarily reducing fat accumulation by promoting lipolysis and enhancing energy expenditure. Research indicates that naringin activates the AMPK signaling pathway and upregulates the expression of lipolytic genes, such as hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), while simultaneously promoting the transcription of genes associated with fatty acid β-oxidation (e.g., CPT1, UCP2), thereby stimulating lipid catabolism. In mouse models of high-fat diet-induced obesity, naringin supplementation significantly inhibited weight gain, reduced liver weight, and altered body composition; the underlying mechanisms involve enhancing the thermogenic activity of brown adipose tissue and inducing the "browning" of inguinal white adipose tissue.

naringin for testosterone

Naringin exerts protective and enhancing effects on testosterone levels, particularly under pathological or stress conditions. In a heat-stress male rat model, naringin supplementation effectively mitigated the stress-induced decline in testosterone and luteinizing hormone; similarly, in a model of diabetes-induced testicular dysfunction, naringin reversed the reduction in testosterone levels through mechanisms involving the regulation of the xanthine oxidase/uric acid signaling pathway and the restoration of redox balance. Regarding dibutyl phthalate-induced testicular injury, naringin significantly increased serum testosterone levels and improved sperm quality. 

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naringin supplement

The application of naringin in the health supplement sector is expanding rapidly, driven primarily by its proven antioxidant and cardiovascular-protective properties. As a dietary supplement, naringin is commonly marketed in capsule or tablet form, offering benefits such as antioxidant support, cardiovascular health maintenance, and metabolic regulation. However, its inherent limitations-namely poor water solubility and low bioavailability-hinder its efficacy; consequently, solid dispersion technology has been adopted to enhance its solubility and absorption rates. Regarding formulation, naringin can be combined with fructose, calcium supplements, and vitamin D3 for bone health products, or paired with ingredients like green tea extract to achieve synergistic effects.

naringin in skincare

Naringin has been developed into various product forms within the cosmetics and skincare sector, including facial masks, serums, eye creams, and multifunctional ingredients. In facial masks, naringin works synergistically with niacinamide (Vitamin B3) and pyridoxine hydrochloride (Vitamin B6); this combination achieves equivalent whitening results while allowing for a reduced dosage of niacinamide, thereby lowering the risk of skin sensitization, and incorporates β-glucan to enhance free-radical scavenging and provide radiation protection. For scalp care, serums featuring naringin (0.5%–4.5%) as the key active ingredient offer multiple benefits, such as oil control, anti-inflammatory soothing, scalp barrier repair, and hair loss reduction, making them suitable for individuals with oily or sensitive scalps as well as those experiencing hair loss.

Naringin exhibits a favorable safety profile at conventional doses, though excessive intake may pose a risk of hepatotoxicity. A six-month chronic toxicity study in rats demonstrated that daily oral administration of naringin at doses up to 1250 mg/kg resulted in no lethality or significant toxicological changes; only slight weight loss and reversible hair loss were observed, establishing a No-Observed-Adverse-Effect Level (NOAEL) greater than 1250 mg/kg/day. However, in vitro studies suggest that high concentrations of naringin (400 µM) can induce hepatocyte injury, characterized by reduced cell viability, elevated ALT and AST levels, and increased expression of the inflammatory cytokines TNF-α and IL-1β. 

Our products adhere strictly to 98% purity standards, utilizing advanced production processes and precise testing procedures to ensure consistent, potent, and contaminant-free ingredients in every batch, ensuring safe, reliable, and top-tier raw materials for our clients' projects.We flexibly adjust powder fineness, carrier solutions, and packaging specifications based on application scenarios (e.g., formulations, food, and cosmetics), precisely matching our clients' R&D needs and production processes to achieve efficient product implementation and differentiated innovation.From raw material selection and application recommendations to regulatory compliance consulting, our team provides comprehensive professional services, making us a reliable partner in the natural ingredient space and helping our clients achieve market success.Buy Naringin powder, contact us at info@kintaibio.com.

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