Matrine Powder

The core active ingredient of Sophora Flavescens Extract is matrine, accompanied by alkaloids such as oxymatrine and sophocarpine. It features broad-spectrum antibacterial, insecticidal, anti-inflammatory and antipruritic effects as well as heat-clearing and dampness-drying properties. It can inhibit the growth of various fungi, bacteria and pests while soothing red, itchy skin and alleviating inflammatory reactions.

In agriculture, it is widely used as a botanical biopesticide for pest control on fruits, vegetables and medicinal herbs, featuring low toxicity and zero residue, which fits green planting standards. In daily chemical and skincare industries, it is incorporated into acne-clearing, soothing, oil-controlling and antipruritic washing and care products to relieve acne, eczema, oily scalp and scalp itching. In the pharmaceutical field, it can be formulated into external preparations to relieve skin itching caused by damp-heat and genital pruritus.

Healthkintai^® has long focused on the R&D and production of botanical pesticide raw materials and skincare ingredients. Matrine powder is our flagship product. Sophora Flavescens Root Extract has a full range of specifications detailed in the table below. Should you require any listed specification or inquire about custom grades, please feel free to contact us at health@kintaibio.com for potential cooperation.

Inner packing details of Matrine

Outer packing details of Matrine

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The international regulatory status of Sophora Flavescens Extract (with total matrine alkaloids/matrine as active ingredients) used as agricultural pesticide raw materials varies significantly by region. In Japan, South Korea, Southeast Asia, Africa and South America, it is officially recognized as a compliant active ingredient for botanical biopesticides, which can undergo independent local pesticide registration and is widely applied in green pest control for fruits, vegetables and medicinal herbs. For customs clearance of exported goods, it is only required to provide COA with qualified pesticide residue and heavy metal test results, MSDS and certificate of origin.

Japan and South Korea recognize Sophora Flavescens Radix Extract as a raw material for traditional Kampo and Korean herbal medicines. Topical preparations may follow simplified registration pathways for quasi-drugs and traditional herbal remedies, whereas oral preparations require complete toxicological and clinical data to pass stringent pharmaceutical approval. The EU, UK, United States, Canada and Australia impose extremely high market access thresholds, where the extract can only be circulated with relatively low compliance requirements as a topical herbal soothing raw material or dietary supplement ingredient.

Sophora Flavescens Root Extract is globally compliant as a cosmetic raw material. In Japan and South

Korea, it is recognized as an approved conventional cosmetic ingredient and can also be used as a functional raw material for quasi-drugs to make mild skincare claims regarding oil control and acne inhibition. It is listed in the CosIng database for the EU and the UK. The United States, Canada and Australia all allow this botanical extract as a general skincare raw material, permitting mild efficacy claims such as soothing, antioxidant and skin repairing effects. Regulatory requirements are relatively loose in Southeast Asia, Africa and South America.

Matrine for Agriculture

• Matrine Insecticide Mode of Action

Matrine has both contact and stomach poisoning effects. After penetrating the pest's body surface via liquid contact or being ingested by pests, it acts on two fronts:

On one hand, it targets the central nervous system of insects by binding to glutamate chloride channels, interfering with acetylcholinesterase and GABA receptors, and blocking normal nerve signal transmission, which first causes spasms in pests and subsequently leads to general nerve paralysis, rendering them immobile and unable to feed;

On the other hand, it damages the permeability of the pest's midgut cell membrane, disrupts cellular ion balance, inhibits key enzymes involved in respiratory metabolism, and coagulates proteins in the pest's epidermis and internal tissues to block its respiratory spiracles. The superposition of multiple physiological injuries quickly suffocates and exhausts pests to death. In addition, matrine can deter pest feeding and disrupt their molting, development and reproduction, achieving comprehensive pest control through short-term lethal effects and long-term population suppression.

• Matrine Antibacterial Mode of Action

Matrine suppresses and kills pathogenic fungi and bacteria infesting crops via multi-target mechanisms: when the agent comes into contact with crop pathogens, it damages their cell walls and membranes, causing leakage of intracellular nutrients and disrupting cellular osmotic balance. Meanwhile, it inhibits key synthetic and metabolic enzymes of pathogens, blocks cell wall formation, energy metabolism and gene replication, restrains the growth and reproduction of hyphae and spores, and interferes with the signaling pathways through which pathogens infect crop tissues. These synergistic effects hinder pathogen spread on crops and alleviate various infectious crop diseases.

Sophora Flavescens Root Extract for Hair

Matrine is a natural plant active ingredient extracted from Sophora flavescens, suitable for daily care of scalp and hair strands to nourish the scalp and improve hair texture.

This botanical ingredient helps soothe scalp discomfort and relieve greasy scalp issues including dandruff, itchiness, oily scalp and redness caused by excessive reproduction of Malassezia. It gently regulates scalp sebum secretion to balance scalp oil and moisture, ease flat greasy roots and sustain long-lasting scalp freshness. It alleviates sensitive irritations triggered by hair perming, dyeing and external environmental stress, and helps maintain the scalp's natural protective barrier. It unclogs follicles blocked by excess sebum, optimizes scalp circulation and reduces hair breakage and shedding resulting from sebum buildup, creating a clean and comfortable growth environment for hair roots.

Sophora Flavescens Root Extract for Skin

Matrine is a natural plant alkaloid extracted from the roots of Sophora flavescens. Mild and skin-friendly, it works well for oily, acne-prone and easily irritated reddish skin with multiple skincare benefits including antibacterial soothing, oil control and skin repair.

It inhibits harmful microorganisms on the skin surface that trigger breakouts and clogged pores, improving blemishes on the face, chest and back. It regulates sebum production to reduce facial oiliness and refine enlarged pores. It soothes discomfort such as redness, itchiness and burning sensations, eases seasonal skin sensitivity, calms irritated skin and repairs fragile skin barriers to minimize recurring breakouts and redness.

It causes less irritation than synthetic antibacterial ingredients and is widely used in skincare products for acne care, oil balancing and sensitive skin soothing.

Matrine for Liver

Matrine exerts bidirectional regulatory pharmacological effects on the liver. When administered at low doses and in accordance with standardized protocols, it delivers hepatoprotective effects: on the one hand, it inhibits the activation of hepatic stellate cells and reduces collagen deposition to block the progression of liver fibrosis; meanwhile, it downregulates the release of inflammatory factors, alleviates inflammatory infiltration and oxidative stress damage in hepatocytes, stabilizes hepatocyte membranes, and lowers transaminase levels, thereby repairing and protecting the liver against hepatitis and liver injuries.

However, excessive, long-term or inappropriate administration leads to hepatotoxicity. Therefore, strict control of dosage and treatment course is required in clinical practice to balance the hepatoprotective benefits and potential risks of liver damage.

Reference: https://pdfs.semanticscholar.org/7b03/0bf0ab117e90f6f570cbc69701d52df91696.pdf

Matrine Insecticide/Pesticide

As a broad-spectrum, low-toxicity and eco-friendly botanical biopesticide, matrine is widely used in the green prevention and control of diseases and pests for crops such as vegetables, fruits, tea and Chinese medicinal materials, making it an important alternative to chemical pesticides.

Matrine Topical Health Care Products

Matrine is legally applicable to all types of topical health care products. As a core natural botanical raw material for external use, it delivers multiple effects including broad-spectrum bacteriostasis, anti-inflammation, skin soothing, acarid inhibition and itch relief. Its safe conventional dosage range is 0.05%–0.5%. It is suitable for a full range of topical health care products such as private part antibacterial lotion, anti-itch ointment and foot bath products, combining mild natural characteristics with long-term bacteriostatic and skin-repairing benefits.

Matrine Daily Chemical Products

Matrine is widely used in all categories of daily chemical and personal care products, with the conventional addition dosage controlled at 0.1%-0.5%. It is compatible with various formulation systems including water-based preparations, serums, creams, hair & body wash products, and oral care items.

For skincare, it is commonly incorporated into anti-acne cleansers, soothing repair masks, oil-control toners and sensitive skin repair creams to relieve inflammatory acne, seborrheic dermatitis and seasonal allergies.

In the washing and care sector, it is added into soaps, shampoos, body washes and antibacterial hand sanitizers. For oral care, it is applied to toothpastes and mouthwashes, serving as a preferred green raw material to replace traditional preservatives and bacteriostatic ingredients.

When you are looking for a reliable supplier to purchase matrine powder, choosing our factory as your direct source offers significant advantages.

As a natural sophora flavescens extract matrine manufacturer equipped with advanced production facilities, Healthkintai^® provides stable supply capacity, strict quality control, and competitive pricing for matrine powder. We deliver flexible procurement solutions and professional global logistics support to our customers. Please feel free to contact us at health@kintaibio.com.

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